| Literature DB >> 32482676 |
Sophie Octavia1,2, Tse Hsien Koh3, Oon Tek Ng2,4,5, Kalisvar Marimuthu2,5,6, Indumathi Venkatachalam7,8, Raymond T P Lin1,2,9, Jeanette W P Teo10.
Abstract
The bla IMI gene is rarely detected outside the Enterobacter genus. Genomic characterization of 87 bla IMI-positive Enterobacter cloacae complex members revealed that the largest phylogenomic clade was made up of E. cloacae subsp. cloacae (71.3%), followed by the newly described species E. bugandensis (13.8%), E. sichuanensis (10.3%), and E. roggenkampii (4.6%). IMI-1 was the predominant carbapenemase variant (86/87, 98.9%). All the bla IMI genes were associated with chromosomally integrated Xer-dependent integrative mobile elements (IMEXs), with two new variants detected.Entities:
Keywords: Enterobacter; Enterobacteriaceae; antimicrobial resistance; carbapenemase; imipenemase; phylogenomics; whole genome
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Year: 2020 PMID： 32482676 PMCID： PMC7526801 DOI： 10.1128/AAC.00510-20
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191