Literature DB >> 26248383

Characterization of a Novel Putative Xer-Dependent Integrative Mobile Element Carrying the bla(NMC-A) Carbapenemase Gene, Inserted into the Chromosome of Members of the Enterobacter cloacae Complex.

Alberto Antonelli1, Marco Maria D'Andrea2, Vincenzo Di Pilato3, Bruno Viaggi4, Francesca Torricelli5, Gian Maria Rossolini6.   

Abstract

An Enterobacter ludwigii strain was isolated during routine screening of a Japanese patient for carriage of carbapenem-resistant Enterobacteriaceae. PCR analysis revealed the blaNMC-A carbapenemase gene. Whole-genome sequencing revealed that blaNMC-A was inserted in the chromosome and associated with a novel 29.1-kb putative Xer-dependent integrative mobile element, named EludIMEX-1. Bioinformatic analysis identified similar elements in the genomes of an Enterobacter asburiae strain and of other Enterobacter cloacae complex strains, confirming the mobile nature of this element.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID: 26248383      PMCID: PMC4576029          DOI: 10.1128/AAC.01452-15

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  31 in total

1.  First identification of blaIMI-1 in an Enterobacter cloacae clinical isolate from France.

Authors:  Thierry Naas; Christian Cattoen; Stéphanie Bernusset; Gaelle Cuzon; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2011-12-27       Impact factor: 5.191

2.  A kinetic study of NMC-A beta-lactamase, an Ambler class A carbapenemase also hydrolyzing cephamycins.

Authors:  S Mariotte-Boyer; M H Nicolas-Chanoine; R Labia
Journal:  FEMS Microbiol Lett       Date:  1996-09-15       Impact factor: 2.742

3.  A5-miseq: an updated pipeline to assemble microbial genomes from Illumina MiSeq data.

Authors:  David Coil; Guillaume Jospin; Aaron E Darling
Journal:  Bioinformatics       Date:  2014-10-22       Impact factor: 6.937

Review 4.  Enterobacter cloacae complex: clinical impact and emerging antibiotic resistance.

Authors:  Maria Lina Mezzatesta; Floriana Gona; Stefania Stefani
Journal:  Future Microbiol       Date:  2012-07       Impact factor: 3.165

5.  Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK.

Authors:  Michel Doumith; Matthew J Ellington; David M Livermore; Neil Woodford
Journal:  J Antimicrob Chemother       Date:  2009-02-20       Impact factor: 5.790

Review 6.  Class A carbapenemases.

Authors:  Jan Walther-Rasmussen; Niels Høiby
Journal:  J Antimicrob Chemother       Date:  2007-06-26       Impact factor: 5.790

7.  Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein.

Authors:  T Naas; P Nordmann
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-02       Impact factor: 11.205

8.  Biochemical properties of a carbapenem-hydrolyzing beta-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli.

Authors:  P Nordmann; S Mariotte; T Naas; R Labia; M H Nicolas
Journal:  Antimicrob Agents Chemother       Date:  1993-05       Impact factor: 5.191

9.  Carbapenemase-producing Enterobacteriaceae in Finland: the first years (2008-11).

Authors:  Monica Österblad; Juha Kirveskari; Antti J Hakanen; Päivi Tissari; Martti Vaara; Jari Jalava
Journal:  J Antimicrob Chemother       Date:  2012-07-31       Impact factor: 5.790

10.  Identification and characterization of microcin S, a new antibacterial peptide produced by probiotic Escherichia coli G3/10.

Authors:  Anke Zschüttig; Kurt Zimmermann; Jochen Blom; Alexander Goesmann; Christoph Pöhlmann; Florian Gunzer
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

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  13 in total

Review 1.  Mobile Genetic Elements Associated with Antimicrobial Resistance.

Authors:  Sally R Partridge; Stephen M Kwong; Neville Firth; Slade O Jensen
Journal:  Clin Microbiol Rev       Date:  2018-08-01       Impact factor: 26.132

2.  Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying blaIMI-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore.

Authors:  Tse H Koh; Nurdyana Binte Abdul Rahman; Jeanette W P Teo; My-Van La; Balamurugan Periaswamy; Swaine L Chen
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

3.  Enterobacter cloacae Complex Isolated from Shrimps from Vietnam Carrying blaIMI-1 Resistant to Carbapenems but Not Cephalosporins.

Authors:  Michael S M Brouwer; Michel Rapallini; Yvon Geurts; Frank Harders; Alex Bossers; Dik J Mevius; Ben Wit; Kees T Veldman
Journal:  Antimicrob Agents Chemother       Date:  2018-06-26       Impact factor: 5.191

Review 4.  Epidemiology of β-Lactamase-Producing Pathogens.

Authors:  Karen Bush; Patricia A Bradford
Journal:  Clin Microbiol Rev       Date:  2020-02-26       Impact factor: 26.132

5.  Carbapenemase-Producing Gram-Negative Bacteria from American Crows in the United States.

Authors:  Iva Kutilova; Adam Valcek; Costas C Papagiannitsis; Darina Cejkova; Martina Masarikova; Veronika Paskova; Lenka Davidova-Gerzova; Petra Videnska; Jaroslav Hrabak; Ivan Literak; Monika Dolejska
Journal:  Antimicrob Agents Chemother       Date:  2020-12-16       Impact factor: 5.191

6.  Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids.

Authors:  David A Boyd; Laura F Mataseje; Ross Davidson; Johannes A Delport; Jeff Fuller; Linda Hoang; Brigitte Lefebvre; Paul N Levett; Diane L Roscoe; Barbara M Willey; Michael R Mulvey
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

Review 7.  The rapid spread of carbapenem-resistant Enterobacteriaceae.

Authors:  Robert F Potter; Alaric W D'Souza; Gautam Dantas
Journal:  Drug Resist Updat       Date:  2016-09-19       Impact factor: 18.500

8.  Molecular characteristics of global β-lactamase-producing Enterobacter cloacae by genomic analysis.

Authors:  Jincao Hu; Jia Li; Chang Liu; Yan Zhang; Hui Xie; Chuchu Li; Han Shen; Xiaoli Cao
Journal:  BMC Microbiol       Date:  2022-10-21       Impact factor: 4.465

9.  Genomic Study of bla IMI-Positive Enterobacter cloacae Complex in Singapore over a Five-Year Study Period.

Authors:  Sophie Octavia; Tse Hsien Koh; Oon Tek Ng; Kalisvar Marimuthu; Indumathi Venkatachalam; Raymond T P Lin; Jeanette W P Teo
Journal:  Antimicrob Agents Chemother       Date:  2020-07-22       Impact factor: 5.191

Review 10.  Xer Site Specific Recombination: Double and Single Recombinase Systems.

Authors:  Fabio Castillo; Amal Benmohamed; George Szatmari
Journal:  Front Microbiol       Date:  2017-03-20       Impact factor: 5.640

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