Literature DB >> 32437735

19-nor-pimaranes from Icacina trichantha.

Brian Guo1, Ming Zhao2, Zhenlong Wu3, Monday M Onakpa4, Joanna E Burdette5, Chun-Tao Che5.   

Abstract

Four new unusual 19-nor-pimarane-type diterpenes were isolated from the tuber of Icacina trichantha (Icacinaceae, Oliv.). The structures were elucidated based on spectroscopic and HRMS analysis. The absolute configurations were determined by electronic circular dichroism. All four compounds are structural analogues of icacinol and humirianthol, but do not demonstrate the same cytotoxic activity. A plausible biogenetic pathway is proposed.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Diterpenoids; Humirianthol; Icacina trichantha; Icacinaceae; Icacinol; Pimarane

Mesh：

Substances：

Year:  2020        PMID： 32437735      PMCID： PMC7384768          DOI： 10.1016/j.fitote.2020.104612

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  28 in total

1.  Structures, biogenetic relationships, and cytotoxicity of pimarane-derived diterpenes from Petalostigma pubescens.

Authors:  Mary H Grace; Yinghua Jin; George R Wilson; Robert M Coates
Journal:  Phytochemistry       Date:  2005-11-18       Impact factor: 4.072

2.  Icacinlactone H and Icacintrichantholide from the Tuber of Icacina trichantha.

Authors:  Ming Zhao; Monday M Onakpa; Bernard D Santarsiero; Xiao-Jun Huang; Xiao-Qi Zhang; Jia Chen; Jian-Jun Cheng; Richard Longnecker; Chun-Tao Che
Journal:  Org Lett       Date:  2015-07-17       Impact factor: 6.005

3.  Ethnobotanical study of plants used in treating hypertension in Edo State of Nigeria.

Authors:  Adebayo Gbolade
Journal:  J Ethnopharmacol       Date:  2012-09-10       Impact factor: 4.360

4.  SpecDis: quantifying the comparison of calculated and experimental electronic circular dichroism spectra.

Authors:  Torsten Bruhn; Anu Schaumlöffel; Yasmin Hemberger; Gerhard Bringmann
Journal:  Chirality       Date:  2013-04       Impact factor: 2.437

5.  Screening of Icacina trichantha extracts for pharmacological activity.

Authors:  I U Asuzu; E E Ugwueze
Journal:  J Ethnopharmacol       Date:  1990-02       Impact factor: 4.360

6.  The antiinflammatory activity of Icacina trichantha tuber.

Authors:  I U Asuzu; S Sosa; R Della Loggia
Journal:  Phytomedicine       Date:  1999-10       Impact factor: 5.340

7.  Cytotoxic diterpenoids from two lianas from the Suriname rainforest.

Authors:  Eba Adou; Russell B Williams; Jennifer K Schilling; Stan Malone; Jan Meyer; Jan H Wisse; Djon Frederik; Delon Koese; Marga C M Werkhoven; Carl E Snipes; Todd L Werk; David G I Kingston
Journal:  Bioorg Med Chem       Date:  2005-11-01       Impact factor: 3.641

8.  Cytotoxic (9βH)-pimarane and (9βH)-17-norpimarane diterpenes from the tuber of Icacina trichantha.

Authors:  Michael Monday Onakpa; Ming Zhao; Tanja Gödecke; Wei-Lun Chen; Chun-Tao Che; Bernard D Santarsiero; Steven M Swanson; Isaac Uzoma Asuzu
Journal:  Chem Biodivers       Date:  2014-12       Impact factor: 2.408

9.  Diterpenes from the roots of Oryza sativa L. and their inhibition activity on NO production in LPS-stimulated RAW264.7 macrophages.

Authors:  Jin-Gyeong Cho; Byeong-Ju Cha; Sang Min Lee; Sabina Shrestha; Rak-Hun Jeong; Dong Sung Lee; Youn-Chul Kim; Dong-Geol Lee; Hee-Cheol Kang; Jiyoung Kim; Nam-In Baek
Journal:  Chem Biodivers       Date:  2015-09       Impact factor: 2.408

10.  Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase.

Authors:  Hee Jin Jung; Hyun Ah Jung; Sam Sik Kang; Je-Hyun Lee; Yoon Sook Cho; Kyong Ho Moon; Jae Sue Choi
Journal:  Arch Pharm Res       Date:  2012-11-09       Impact factor: 4.946
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