Literature DB >> 32273968

The Combination of Antimicrobial Photodynamic Therapy and Photobiomodulation Therapy for the Treatment of Palatal Ulcers: A Case Report.

Rafael Maya1, Lorena Lúcia Costa Ladeira2, Juliana Elaine Pinto Maya3, Letícia Machado Gonçalves Mail4, Sandra Kalil Bussadori5, Marco Aurélio Benini Paschoal6.   

Abstract

Introduction: One of the unexpected side effects of the Haas type palatal expander is ulcers progressing to necrotic lesions in the palatal area due to poor hygiene. The use of antibiotic therapy is mandatory. However, long periods of healing/pain and the need for a systemic host response with the aid of metabolization, especially in children, are issues that should be taken into account in the management of this type of injury. Since phototherapy modalities (antimicrobial photodynamic therapy [aPDT] and photobiomodulation therapy [PBMT]) are able to enhance and accelerate the healing process and reduce the bacterial load, this case report aimed to describe the use of the above-mentioned therapies to treat palatal ulcers occurring during orthodontic expansion. Case Report: The patient, a 10-year-old boy, with a chief complaint of bleeding and continuous pain in the region of his expander was verified on a follow-up visit. After a dental examination, the expander was removed and two necrotic lesions which were in contact with the acrylic part of the tooth-tissue expander were found in the palatal region. The proposal was to use one aPDT session with methylene blue followed by 4 sessions of PBMT with a red laser diode. On the 5th day, reorganized tissue was verified, with the absence of bleeding, swelling, and pain. On the 20th day of follow-up, the area showed no signs of inflammation, healthy tissue without any pathological clinical symptoms, and complete wound healing.
Conclusion: The concomitant use of PBMT and aPDT therapies may be considered feasible as an adjunct treatment to manage palatal ulcers resulting from the incorrect use of tooth-tissue types of expanders.
Copyright © 2020 J Lasers Med Sci.

Entities:  

Keywords:  Low-level laser therapy; Oral ulcer; Palatal expansion technique

Year:  2020        PMID: 32273968      PMCID: PMC7118493          DOI: 10.34172/jlms.2020.38

Source DB:  PubMed          Journal:  J Lasers Med Sci        ISSN: 2008-9783


  32 in total

1.  Rapid palatal expansion: a comparison of two appliances.

Authors:  Amanda do Prado Rodrigues; André da Costa Monini; Luiz Gonzaga Gandini; Ary dos Santos-Pinto
Journal:  Braz Oral Res       Date:  2012 May-Jun

2.  Cephalometric evaluation of rapid and slow maxillary expansion in patients with BCLP: Secondary data analysis from a randomized clinical trial.

Authors:  Leonardo Gregório; Arthur César de Medeiros Alves; Araci Malagodi de Almeida; Rodrigo Naveda; Guilherme Janson; Daniela Garib
Journal:  Angle Orthod       Date:  2019-02-11       Impact factor: 2.079

3.  Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination.

Authors:  Hérica Adad Ricci Donato; Sebastião Pratavieira; Clovis Grecco; Aldo Brugnera-Júnior; Vanderlei Salvador Bagnato; Cristina Kurachi
Journal:  Photomed Laser Surg       Date:  2016-11-07       Impact factor: 2.796

Review 4.  Contribution of photodynamic therapy in wound healing: A systematic review.

Authors:  Vanessa Nesi-Reis; Daniele Stéfanie Sara Lopes Lera-Nonose; Jully Oyama; Marielle Priscila Paula Silva-Lalucci; Izabel Galhardo Demarchi; Sandra Mara Alessi Aristides; Jorge Juarez Vieira Teixeira; Thaís Gomes Verzignassi Silveira; Maria Valdrinez Campana Lonardoni
Journal:  Photodiagnosis Photodyn Ther       Date:  2017-12-28       Impact factor: 3.631

5.  Effects of low-power laser irradiation (LPLI) at different wavelengths and doses on oxidative stress and fibrogenesis parameters in an animal model of wound healing.

Authors:  Paulo Cesar Lock Silveira; Luciano A Silva; Tiago P Freitas; Alexandra Latini; Ricardo A Pinho
Journal:  Lasers Med Sci       Date:  2010-09-24       Impact factor: 3.161

6.  830 nm light-emitting diode low level light therapy (LED-LLLT) enhances wound healing: a preliminary study.

Authors:  Pok Kee Min; Boncheol Leo Goo
Journal:  Laser Ther       Date:  2013

7.  The use of antimicrobial photodynamic therapy in oral injuries of a pediatric patient with myelodysplastic syndrome: case report.

Authors:  Maria Cecília Freire de Melo; Thuanny Silva de Macedo; Julianelly Alves Biserra; Karina Luz Cavalcanti Rodrigues; Mônica Cruz; Aurora Karla de Lacerda Vidal
Journal:  Spec Care Dentist       Date:  2018-03-06

8.  Histological Evaluation of Wound Healing Process after Photodynamic Therapy of Rat Oral Mucosal Ulcer.

Authors:  Parviz Deyhimi; Heidar Khademi; Reza Birang; Mohammad Akhoondzadeh
Journal:  J Dent (Shiraz)       Date:  2016-03

9.  The impact of photodynamic therapy on the viability of Streptococcus mutans in a planktonic culture.

Authors:  I M Bevilacqua; R A Nicolau; S Khouri; A Brugnera; G R Teodoro; R A Zângaro; M T T Pacheco
Journal:  Photomed Laser Surg       Date:  2007-12       Impact factor: 2.796

10.  Impact of low-level laser therapy on the dynamics of pressure ulcer-induced changes considering an infectious agent and cathelicidin LL-37 concentration: a preliminary study.

Authors:  Małgorzata Brauncajs; Krzysztof Ksiąszczyk; Anna Lewandowska-Polak; Katarzyna Gorzela; Janina Grzegorczyk
Journal:  Postepy Dermatol Alergol       Date:  2018-11-08       Impact factor: 1.837

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  3 in total

Review 1.  Photobiomodulation (PBMT) and antimicrobial photodynamic therapy (aPDT) in oral manifestations of patients infected by Sars-CoV-2: systematic review and meta-analysis.

Authors:  Juliano Abreu Pacheco; Kelly Fernanda Molena; Camila Raíssa Oliveira Gontijo Martins; Silmara Aparecida Milori Corona; Maria Cristina Borsatto
Journal:  Bull Natl Res Cent       Date:  2022-05-16

Review 2.  Advances in photosensitizer-related design for photodynamic therapy.

Authors:  Zhaojie Zhou; Ling Zhang; Zhirong Zhang; Zhenmi Liu
Journal:  Asian J Pharm Sci       Date:  2021-05-02       Impact factor: 6.598

Review 3.  Antimicrobial Photodynamic Therapy: Latest Developments with a Focus on Combinatory Strategies.

Authors:  Raphaëlle Youf; Max Müller; Ali Balasini; Franck Thétiot; Mareike Müller; Alizé Hascoët; Ulrich Jonas; Holger Schönherr; Gilles Lemercier; Tristan Montier; Tony Le Gall
Journal:  Pharmaceutics       Date:  2021-11-24       Impact factor: 6.321

  3 in total

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