| Literature DB >> 32267963 |
C C M Lee1, S Thampi1, B Lewin2, T J D Lim1, B Rippin3, W H Wong1, R V Agrawal1.
Abstract
In December 2019, a cluster of atypical pneumonia cases were reported in Wuhan, China, and a novel coronavirus elucidated as the aetiologic agent. Although most initial cases occurred in China, the disease, termed coronavirus disease 2019, has become a pandemic and continues to spread rapidly with human-to-human transmission in many countries. This is the third novel coronavirus outbreak in the last two decades and presents an ensuing healthcare resource burden that threatens to overwhelm available healthcare resources. A study of the initial Chinese response has shown that there is a significant positive association between coronavirus disease 2019 mortality and healthcare resource burden. Based on the Chinese experience, some 19% of coronavirus disease 2019 cases develop severe or critical disease. This results in a need for adequate preparation and mobilisation of critical care resources to anticipate and adapt to a surge in coronavirus disease 2019 case-load in order to mitigate morbidity and mortality. In this article, we discuss some of the peri-operative and critical care resource planning considerations and management strategies employed in a tertiary academic medical centre in Singapore in response to the coronavirus disease 2019 outbreak.Entities:
Keywords: COVID-19; critical care; healthcare; peri-operative; resource management
Mesh:
Year: 2020 PMID: 32267963 PMCID: PMC7262214 DOI: 10.1111/anae.15074
Source DB: PubMed Journal: Anaesthesia ISSN: 0003-2409 Impact factor: 12.893
Comparison of critical care facilities and incidence of COVID‐19 12, 17, 18
| Country | Critical care unit beds | Critical care beds per 100,000 population | Total cases | Total deaths | Case‐fatality rate |
|---|---|---|---|---|---|
| Singapore | 671 | 11.4 | 683 | 2 | 0.3% |
| China | 49,453 | 3.6 | 82,078 | 3,298 | 4.0% |
| France | 7,540 | 11.6 | 28,786 | 1,695 | 5.9% |
| Germany | 23,890 | 29.2 | 42,288 | 253 | 0.6% |
| Italy | 7,550 | 12.5 | 80,539 | 8,165 | 10.1% |
| Spain | 4,479 | 9.7 | 56,188 | 4,089 | 7.3% |
| UK | 4,114 | 6.6 | 11,662 | 578 | 5.0% |
Segregation and social distancing measures
| Considerations | Practical measures |
|---|---|
| Inter‐hospital segregation |
Personnel with duties at > 1 hospital restricted to one hospital. 14‐day quarantine period for personnel redeployed from one hospital to another where possible, allows time for symptom manifestation to reduce the risk of nosocomial transmission to the receiving hospital from asymptomatic individuals incubating the virus. Suspension of visiting specialists and locums who are employed at > 1 hospital. Restrict unnecessary medical devices or drug representative entry. |
| Intra‐hospital segregation |
Departmental segregation into teams with an equivalent number of personnel and skill mix. Separate ward and operating theatre teams. Separate personnel caring for suspect or diagnosed COVID‐19 patients from those providing routine care. Shift or rotation system. |
| Reduced face‐to‐face interaction |
Reduce unnecessary at‐work and after‐work social interaction. Creation of additional, separate rest areas with adequate distancing between individuals of 1 metre. Staggered meal times and avoidance of food sharing. Suspension of face‐to‐face group gatherings including department teaching events and meetings. Use of web‐based conferencing applications for discussions. |
Institutional guidelines on use of personal protective equipment for healthcare workers
| Patient category | Risk activity | Recommendation |
|---|---|---|
| Suspected or diagnosed COVID‐19 patients | Non‐AGP (including regional anaesthesia and monitored anaesthetic care). |
Negative‐pressure environment with a high rate of air exchanges (20 per hour) preferred. Full PPE (i.e. N95 respirator, eye‐protection, cap, gloves, fluid‐resistant gown and boot covers). |
| AGP (including intubation, extubation, supraglottic airway insertion and removal, bronchoscopy and airway surgery). |
Negative‐pressure environment with a high rate of air exchanges (20 per hour) preferred. Full PPE and PAPR are provided for all personnel within 2 m. Keep number of personnel in the room minimum during AGPs. Surgeons, scrub nurses and operating room assistants to wait outside, with PPE donned during AGPs. Only two staff to manage the airway. The most experienced anaesthetist or intensivist to instrument the airway. | |
| Asymptomatic and non‐suspect patients | Non‐AGP (including regional anaesthesia and monitored anaesthetic care). | Surgical masks. |
| AGP (including intubation, extubation, supraglottic airway insertion and removal, bronchoscopy and airway surgery). | N95 respirators and goggles or face‐shield. |
AGP, aerosol generating procedure; PPE, personal protective equipment; PAPR, powered air‐purifying respirator.
Recommendations to optimise institutional stockpiles and inventory
| Preparation |
Early inventory assessment and identification of alternative logistic channels for procurement once a potential pandemic threat is identified. Inventory transparency is required to ensure equal distribution and identification of deficiencies. |
| Ration |
Conduct rationing or controlled distribution for scarce commodities (e.g. facemasks, face shields, N95 respirators and PPE). Eliminate non‐essential staff for tasks or procedures where possible to reduce PPE required. |
| Conserve |
Avoid unnecessary use of equipment, drugs and disposables. Avoid unnecessary blood and blood component transfusions, consider recombinant blood product therapy and other blood conservation techniques. Cancel non‐essential, non‐emergency procedures and services. Protocols for care, stick to evidence‐based recommendations. |
| Prioritise use |
Reserve disposable single‐use equipment (e.g. videolaryngoscopy blades, breathing circuits) for suspected and confirmed COVID‐19 patients. ICU ventilators should be used for patients with ARDS requiring high ventilatory settings or advanced ventilatory strategies. Portable ventilators or anaesthetic machines can be used for other patients with lower requirements. |
| Triage | Triage and prioritisation of COVID‐19 patients based on severity and prognosis may be required for resource allocation when levels become critical. |
| Extend supply | With appropriate precautions, such as keeping masks and respirators in containers between uses during a shift, the shelf‐life of certain disposables can be prolonged for limited re‐use. |
| Mobilise reserves | Activation of institutional emergency‐preparedness stockpiles reserved for mass casualty incidents. |
| Consider innovation | Accept novel use and re‐purposing of limited available resources with attention to healthcare worker and patient safety. |
| National effort |
Utilise healthcare cluster‐level or national‐level reserves and solutions for procurement. Consider mobilisation of reserves from other organisations such as military disaster‐relief and humanitarian aid stockpiles. |
ARDS, acute respiratory distress syndrome; PPE, personal protective equipment.
Figure 1Reduction of daily total (solid line), elective (dots and dashes) and emergency (dotted line) surgical case‐load in relation to number of admitted (blue bars) and cumulative total (teal bars) coronavirus disease 2019 patients. Elective surgeries are not performed on weekends and national holidays, which have been omitted from the x‐axis. () Total surgeries; ()Elective surgeries; ()Emergency surgeries; () Admitted COVID‐19 patients; ()Cumulative total COVID‐19 patients.
Figure 2Pandemic expansion schematic for generation of critical care bed space, involving expansion of the cohort intensive care unit into three other adjacent units, with decanting of the high dependency units into the repurposed ambulatory surgical complex. Bed numbers are indicated at the lower right of each unit, representing a total of 176 critical care beds. Each arrow represents activation of the next tier, triggered at 80% capacity of the previous tier. OR, operating room; PACU, post‐anaesthesia care unit.
Figure 3Tiered generation of additional total critical care unit bed space (shaded bars) compared to pre‐crisis levels. Changes in the proportion of clean intensive care unit (ICU) (dotted bars), cohort ICU (striped bars) and expanded clean High dependency units (checked bars) beds are demonstrated according to according to implementation phase. Abbreviations: ambulatory surgical complex (ASC). () total critical care unit bed space; ()clean ICU bed space; () cohort ICU bed space; () expanded clean HDU bed space.
Figure 4Predicted generation of additional critical care unit bed space (dotted area), compared to pre‐crisis baseline (shaded areas), based on the conversion of the ambulatory surgical complex into a high dependency unit for decanted patients. Additional facilities (striped areas) that may be utilised include re‐purposing suitable ward isolation rooms, elective operating rooms and post‐anaesthetic recovery areas as the pandemic progresses. () pre‐crisis baseline; ()additional critical care unit bed space; () additional facilities that may be utilised.
Manpower strategies to maintain critical care staffing requirements
| Staffing | Potential manpower sources and measures |
|---|---|
| Physician | Redeploy specialists with formal ICU training and accreditation, but not currently working in critical care units such as anaesthetists and pulmonologists into ICUs. |
| Anaesthetists without formal critical care accreditation but recent, substantial critical care experience may take certain supervisory and leadership roles in the ICU under supervision by an accredited intensivist. | |
| Anaesthetists without formal critical care accreditation and no recent critical care experience may assist in ICU care at registrar level. | |
| Redeploy anaesthesia and medical registrars and trainees with critical care experience and training to ICUs and HDUs, especially with a reduction in surgical load. | |
| Junior physicians from other disciplines with critical care or ICU exposure as part of their training programme such as general surgical trainees who can assist in administrative duties and basic ICU‐related care under direct supervision of an intensivist. | |
| Step‐down of specialist physicians of other disciplines and surgeons to assist in ICU* and HDU duties in appropriate capacities. | |
| Nursing | Redeploy nursing staff with prior critical care training and experience, but not currently working in critical care areas. |
| Redeploy nursing staff currently working in HDUs into ICUs. | |
| Nurses from surgical units such as anaesthetic and recovery nurses who are familiar with a critical care environment and advanced physiological monitoring, may be deployed into ICUs and HDUs. | |
| Nurses from other backgrounds such as outpatient clinics, which will see an anticipated drop in case load can be redeployed into general wards or HDUs. | |
| Agency nurses not part of the hospital permanent nursing staff can assist in general wards. | |
| General | Redeployment of manpower from wards and clinics. |
| Reduce during office hours manpower with a reduction in non‐essential services, and conversion to a shift‐work system. | |
| Conversion to longer shifts (e.g. 8–12‐h shifts), and accept a reduced staffing relief factor. | |
| Recall of medical staff on overseas training programmes. | |
| Recall of staff on pre‐approved annual leave. | |
| Utilisation of retired staff with valid certifications, and preferably recent experience. | |
| Utilisation of personnel in administrative roles such as research or education. | |
| Consider redeploying personnel currently in private practice or other agencies into public health institutions. |
ICU, intensive care unit; HDU, high dependency unit.
Figure 5Current pre‐crisis (solid fill) and projected increase (dotted fill) physician manpower for additional critical care areas, assuming maintenance of patient care. () pre‐crisis physician manpower; ()projected physician manpower.
Figure 6Current pre‐crisis (solid fill) and projected increase (dotted fill) nursing manpower for additional critical care areas, assuming maintenance of patient care. () pre‐crisis nursing manpower; () projected nursing manpower.