Literature DB >> 32256003

Lower limb lengthening and deformity correction in polyostotic fibrous dysplasia using external fixation and flexible intramedullary nailing.

Arnold Popkov1, Anna Aranovich1, Alexander Antonov1, Pierre Journeau2, Pierre Lascombes3, Dmitry Popkov1.   

Abstract

The study describes preliminary experience of the use of external fixators for limb lengthening and deformity correction in combination with flexible intramedullary nailing in management of polyostotic fibrous dysplasia. PATIENTS AND METHODS: The retrospective study included 8 patients (mean age 11.6 ± 3.38 years; range 7-17 years) with polyostotic fibrous dysplasia operated on using external circular frame and flexible intramedullary nailing. Mean follow-up was 2.6 years. Surgical technique consisted of percutaneous osteotomy of a segment and application of circular external frame. The intramedullary nailing was done using two bent nails. Hydroxyapatite-coated nails were applied in three patients; five patients had titanium nails. Amount of lengthening (cm and %), amount of deformity correction, duration of external fixator use, index of external fixation, "nail/medullary canal at narrowest site" ratio, "nail-medullary canal at osteotomy site" ratio were analyzed. Results and complications were assessed according to Lascombes's classification.
RESULTS: The mean amount of lengthening was 4.5 cm (or 13.7 ± 6.0% per segment). This gave a mean external fixation index of 32.5 ± 13.97 days/cm. The mean ratio of IM nail diameter/medullary canal diameter at the narrowest site was 0.22 ± 0.07 (range, 0.125-0.3 mm). No migration of IM nails into medullary canal were noticed. But in one case there was external migration of Ti-nail. In a year after frame removal, the results of treatment were classified as grade I in 7 cases and IIb in one case.At the latest follow-up control, mechanical axis deviation was found within normal limits in six patients. Two patients had excessive MAD of 11 and 28 mm. In the first case a partial varus deformity recurrence occurred at middle shaft site where a large dysplastic zone was presented. In the second case, a specific shepherd's crook deformity developed and caused excessive MAD. Mean lower limb length discrepancy varied from 1 to 15 mm.
CONCLUSION: There are advantages of using elastic intramedullary nailing and external fixation in the treatment of limb length discrepancy and deformity of long bones in patients with PFD. This strategy ensures reduced external fixation time and high accuracy of alignment. Intramedullary nails left in situ, especially nails with HA-coating, seem to prevent deformity recurrence and stimulate remodeling in dysplastic fibrous zones.
© 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  External fixation; Fibrous dysplasia; Flexible intramedullary nailing

Year:  2020        PMID: 32256003      PMCID: PMC7125318          DOI: 10.1016/j.jor.2020.03.014

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  19 in total

Review 1.  Surgery for fibrous dysplasia.

Authors:  Robert P Stanton
Journal:  J Bone Miner Res       Date:  2006-12       Impact factor: 6.741

2.  Classification of complications after progressive long bone lengthening: proposal for a new classification.

Authors:  P Lascombes; D Popkov; H Huber; T Haumont; P Journeau
Journal:  Orthop Traumatol Surg Res       Date:  2012-09-13       Impact factor: 2.256

Review 3.  The use of flexible intramedullary nails in limb lengthening.

Authors:  Arnold Popkov; Patrick Foster; Alexander Gubin; Dmitry Borzunov; Dmitry Popkov
Journal:  Expert Rev Med Devices       Date:  2017-08-18       Impact factor: 3.166

4.  Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types.

Authors:  E N Bolbasov; D A Popkov; N A Kononovich; E N Gorbach; I A Khlusov; A S Golovkin; K S Stankevich; V P Ignatov; V M Bouznik; Y G Anissimov; S I Tverdokhlebov; A V Popkov
Journal:  Biomed Mater       Date:  2019-01-07       Impact factor: 3.715

5.  Results of deformity correction in children with X-linked hereditary hypophosphatemic rickets by external fixation or combined technique.

Authors:  Arnold Popkov; Anna Aranovich; Dmitry Popkov
Journal:  Int Orthop       Date:  2015-07-07       Impact factor: 3.075

6.  Activating mutations of the stimulatory G protein in the McCune-Albright syndrome.

Authors:  L S Weinstein; A Shenker; P V Gejman; M J Merino; E Friedman; A M Spiegel
Journal:  N Engl J Med       Date:  1991-12-12       Impact factor: 91.245

7.  Treatment of benign bone tumours using external fixation.

Authors:  H Tsuchiya; A F Morsy; H Matsubara; K Watanabe; M E Abdel-Wanis; K Tomita
Journal:  J Bone Joint Surg Br       Date:  2007-08

8.  The surgical management of fibrous dysplasia of bone.

Authors:  Robert P Stanton; Ernesto Ippolito; Dempsey Springfield; Lynn Lindaman; Shlomo Wientroub; Arabella Leet
Journal:  Orphanet J Rare Dis       Date:  2012-05-24       Impact factor: 4.123

Review 9.  Current approaches to flexible intramedullary nailing for bone lengthening in children.

Authors:  Dmitry Popkov; Pierre Lascombes; Pierre Journeau; Arnold Popkov
Journal:  J Child Orthop       Date:  2016-11-08       Impact factor: 1.548

Review 10.  Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium.

Authors:  Muhammad Kassim Javaid; Alison Boyce; Natasha Appelman-Dijkstra; Juling Ong; Patrizia Defabianis; Amaka Offiah; Paul Arundel; Nick Shaw; Valter Dal Pos; Ann Underhil; Deanna Portero; Lisa Heral; Anne-Marie Heegaard; Laura Masi; Fergal Monsell; Robert Stanton; Pieter Durk Sander Dijkstra; Maria Luisa Brandi; Roland Chapurlat; Neveen Agnes Therese Hamdy; Michael Terrence Collins
Journal:  Orphanet J Rare Dis       Date:  2019-06-13       Impact factor: 4.123

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