Literature DB >> 26150332

Results of deformity correction in children with X-linked hereditary hypophosphatemic rickets by external fixation or combined technique.

Arnold Popkov1, Anna Aranovich1, Dmitry Popkov2.   

Abstract

BACKGROUND: The operative procedures to correct multiplanar bone deformities may be indicated for prevention of secondary orthopaedic complications in children with X-linked hereditary hypophosphatemic rickets (XHPR). Different problems related to surgical correction were reported: increased rate of non-union, delayed union, recurrent deformity, deep intramedullary infection, refracture, nerve palsy, and pin tract infection. The aim of this retrospective study was comparison of results of correction in children with XHPR who underwent the treatment with either the Ilizarov device alone or a combined technique: the Ilizarov fixator with flexible intramedullary nailing (FIN) with hydroxyapatite bioactive coating and FIN.
MATERIAL AND METHODS: We retrospectively analysed 47 cases (children of age under 14 years) affected by XHPR. Simultaneous deformity correction in femur and tibia was performed with the Ilizarov device (group I) or the combined method (group II). This article is based on the results of a historical comparative retrospective study from the same institution.
RESULTS: The duration of external fixation is noted to be shorter applying the combined technique: 124.7 days (group I) vs 87.4 days (group II). In both groups deformity correction was achieved with a proper alignment. Nevertheless, while a child continues to grow during long-term follow-up, deviations of the mechanic axis from the centre of the knee joint have been developing again and values of mLDFA, mMPTA have become pathologic in the most of the cases. In group I location of a newly developed deformity resembled a pre-operative one, whereby both diaphyseal and metaphyseal parts were deformed. In group II in all the cases an apex of deformity was located in distal metadiaphyseal zone of the femur and proximal metadiaphyseal zone of the tibia. It is important to note that all of those in group II were out of the zone of the intramedullary nail.
CONCLUSION: Simultaneous correction of femoral and tibial deformities by means of circular external fixators is preferable. Application of a combined osteosynthesis allows to considerably reduce the duration of external fixation and decrease the number of complications. There were no recurrent deformities in parts of bone reinforced by intramedullary nails.

Entities:  

Keywords:  Deformity correction; Flexible intramedullary nailing; Hydroxyapatite bioactive coating; Ilizarov fixator; X-linked hereditary hypophosphatemic rickets

Mesh:

Year:  2015        PMID: 26150332     DOI: 10.1007/s00264-015-2814-7

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  33 in total

1.  Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism.

Authors:  Takashi Shimada; Yuji Yamazaki; Motoo Takahashi; Hisashi Hasegawa; Itaru Urakawa; Takeshi Oshima; Kaori Ono; Makoto Kakitani; Kazuma Tomizuka; Toshiro Fujita; Seiji Fukumoto; Takeyoshi Yamashita
Journal:  Am J Physiol Renal Physiol       Date:  2005-07-05

2.  Principles and results of corrective lower limb osteotomies for patients with vitamin D-resistant hypophosphatemic rickets.

Authors:  M Rubinovitch; S E Said; F H Glorieux; R L Cruess; E Rogala
Journal:  Clin Orthop Relat Res       Date:  1988-12       Impact factor: 4.176

3.  [Long term bone behavior in total primary hip arthroplasty with a fully hydroxyapatite-coated femoral stem: a continuous series of 120 cases with twelve years follow-up].

Authors:  J-C Chatelet; L Setiey
Journal:  Rev Chir Orthop Reparatrice Appar Mot       Date:  2004-11

4.  Deformity correction for vitamin D-resistant hypophosphatemic rickets of adults.

Authors:  Hidenori Matsubara; Hiroyuki Tsuchiya; Tamon Kabata; Keisuke Sakurakichi; Koji Watanabe; Katsuro Tomita
Journal:  Arch Orthop Trauma Surg       Date:  2007-12-21       Impact factor: 3.067

5.  Healing of bone disease in X-linked hypophosphatemic rickets/osteomalacia. Induction and maintenance with phosphorus and calcitriol.

Authors:  R M Harrell; K W Lyles; J M Harrelson; N E Friedman; M K Drezner
Journal:  J Clin Invest       Date:  1985-06       Impact factor: 14.808

6.  Osteotomy and intramedullary nailing for the correction of progressive deformity in vitamin D-resistant hypophosphataemic rickets.

Authors:  K S Eyres; J Brown; D L Douglas
Journal:  J R Coll Surg Edinb       Date:  1993-02

7.  Comparative clinical study on deformity correction accuracy of different external fixators.

Authors:  Ilker Eren; Levent Eralp; Mehmet Kocaoglu
Journal:  Int Orthop       Date:  2013-09-26       Impact factor: 3.075

8.  Hip and knee arthroplasty in hypophosphatemic rickets.

Authors:  A Noelle Larson; Robert T Trousdale; Mark W Pagnano; Arlen D Hanssen; David G Lewallen; Joaquin Sanchez-Sotelo
Journal:  J Arthroplasty       Date:  2009-08-12       Impact factor: 4.757

9.  [Elastic sliding central medullary nailing with osteogenesis imperfecta. Fourteen cases at eight years follow-up].

Authors:  B Boutaud; J-M Laville
Journal:  Rev Chir Orthop Reparatrice Appar Mot       Date:  2004-06

10.  Metabolic and orthopedic management of X-linked vitamin D-resistant hypophosphatemic rickets.

Authors:  Sandro F Fucentese; Thomas J Neuhaus; Leonhard E Ramseier; G Ulrich Exner
Journal:  J Child Orthop       Date:  2008-07-26       Impact factor: 1.548

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  10 in total

1.  Lower limb lengthening and deformity correction in polyostotic fibrous dysplasia using external fixation and flexible intramedullary nailing.

Authors:  Arnold Popkov; Anna Aranovich; Alexander Antonov; Pierre Journeau; Pierre Lascombes; Dmitry Popkov
Journal:  J Orthop       Date:  2020-03-28

Review 2.  Contribution of G.A. Ilizarov to bone reconstruction: historical achievements and state of the art.

Authors:  Alexander V Gubin; Dmitry Y Borzunov; Larisa O Marchenkova; Tatiana A Malkova; Irina L Smirnova
Journal:  Strategies Trauma Limb Reconstr       Date:  2016-07-18

Review 3.  Current approaches to flexible intramedullary nailing for bone lengthening in children.

Authors:  Dmitry Popkov; Pierre Lascombes; Pierre Journeau; Arnold Popkov
Journal:  J Child Orthop       Date:  2016-11-08       Impact factor: 1.548

4.  Bioactivity and osteointegration of hydroxyapatite-coated stainless steel and titanium wires used for intramedullary osteosynthesis.

Authors:  Arnold V Popkov; Elena N Gorbach; Natalia A Kononovich; Dmitry A Popkov; Sergey I Tverdokhlebov; Evgeniy V Shesterikov
Journal:  Strategies Trauma Limb Reconstr       Date:  2017-04-06

5.  Outcomes of orthopedic surgery in a cohort of 49 patients with X-linked hypophosphatemic rickets (XLHR).

Authors:  A Gizard; A Rothenbuhler; Z Pejin; G Finidori; C Glorion; B de Billy; A Linglart; P Wicart
Journal:  Endocr Connect       Date:  2017-11       Impact factor: 3.335

6.  Rotational and translational osteotomy for treatment of severe deformity in hypophosphatemic rickets: A case report.

Authors:  Jin Li; Saroj Rai; Renhao Ze; Xin Tang; Ruikang Liu; Pan Hong
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.889

7.  Use of flexible intramedullary nailing in combination with an external fixator for a postoperative defect and pseudarthrosis of femur in a girl with osteogenesis imperfecta type VIII: a case report.

Authors:  Dmitry Popkov
Journal:  Strategies Trauma Limb Reconstr       Date:  2018-09-29

Review 8.  Consensus Recommendations for the Diagnosis and Management of X-Linked Hypophosphatemia in Belgium.

Authors:  Michaël R Laurent; Jean De Schepper; Dominique Trouet; Nathalie Godefroid; Emese Boros; Claudine Heinrichs; Bert Bravenboer; Brigitte Velkeniers; Johan Lammens; Pol Harvengt; Etienne Cavalier; Jean-François Kaux; Jacques Lombet; Kathleen De Waele; Charlotte Verroken; Koenraad van Hoeck; Geert R Mortier; Elena Levtchenko; Johan Vande Walle
Journal:  Front Endocrinol (Lausanne)       Date:  2021-03-19       Impact factor: 5.555

9.  The orthopaedic management of lower limb deformity in hypophosphataemic rickets.

Authors:  A Horn; J Wright; D Bockenhauer; W Van't Hoff; D M Eastwood
Journal:  J Child Orthop       Date:  2017-08-01       Impact factor: 1.548

10.  A new technique for correction of leg length discrepancies in combination with complex axis deformities of the lower limb using a lengthening nail and a locking plate.

Authors:  C N Steiger; U Lenze; A H Krieg
Journal:  J Child Orthop       Date:  2018-10-01       Impact factor: 1.548

  10 in total

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