Literature DB >> 32250871

Goals of COPD treatment: Focus on symptoms and exacerbations.

Claus F Vogelmeier1, Miguel Román-Rodríguez2, Dave Singh3, MeiLan K Han4, Roberto Rodríguez-Roisin5, Gary T Ferguson6.   

Abstract

Chronic obstructive pulmonary disease (COPD) is currently a leading cause of death worldwide, and its burden is expected to rise in the coming years. Common COPD symptoms include dyspnea, cough and/or sputum production. Some patients may experience acute worsening of symptoms (known as an exacerbation), and therefore require additional therapy. Exacerbations are mainly triggered by respiratory infections and environmental factors. Healthcare professionals face many challenges in COPD management, including the heterogeneity of the disease and under-reporting of symptoms. The authors review these challenges and provide recommendations for the best methods to assess COPD. The goals of COPD treatment include recognising the impact that both symptoms and exacerbations have on patients' lives when considering optimal patient-focused management. The review discusses the need for COPD management strategies to include both pharmacologic and non-pharmacologic approaches and provides recommendations for monitoring treatment outcomes and adjusting management strategies accordingly. Novel treatment strategies including precision medicine and point-of-care testing are also discussed.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  COPD; Exacerbations; GOLD; Management goals; Symptoms

Year:  2020        PMID: 32250871     DOI: 10.1016/j.rmed.2020.105938

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  25 in total

1.  Monthly Follow-Ups of Functional Status in People with COPD: A Longitudinal Study.

Authors:  Vânia Rocha; Jorge Cabral; Sara Souto-Miranda; Ana Filipa Machado; Cristina Jácome; Joana Cruz; Vitória Martins; Paula Simão; Maria Aurora Mendes; Vera Afreixo; Alda Marques
Journal:  J Clin Med       Date:  2022-05-28       Impact factor: 4.964

2.  Increased Expression of LASI lncRNA Regulates the Cigarette Smoke and COPD Associated Airway Inflammation and Mucous Cell Hyperplasia.

Authors:  Marko Manevski; Dinesh Devadoss; Christopher Long; Shashi P Singh; Mohd Wasim Nasser; Glen M Borchert; Madhavan N Nair; Irfan Rahman; Mohan Sopori; Hitendra S Chand
Journal:  Front Immunol       Date:  2022-06-14       Impact factor: 8.786

3.  Efficacy of salmeterol and magnesium isoglycyrrhizinate combination treatment in rats with chronic obstructive pulmonary disease.

Authors:  Ye Yang; Lei Huang; Chongchong Tian; Bingjun Qian
Journal:  Sci Rep       Date:  2022-07-19       Impact factor: 4.996

4.  Periodontal Status and Microbiologic Pathogens in Patients with Chronic Obstructive Pulmonary Disease and Periodontitis: A Case-Control Study.

Authors:  Xuan Zhou; Jitian Wang; Wenyan Liu; Xuan Huang; Yiqing Song; Zuomin Wang; Xingyuan Jia
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-09-03

5.  The CT pulmonary vascular parameters and disease severity in COPD patients on acute exacerbation: a correlation analysis.

Authors:  Tao Yang; Chihua Chen; Zhongyuanlong Chen
Journal:  BMC Pulm Med       Date:  2021-01-20       Impact factor: 3.317

6.  Dynamic Increase of Red Cell Distribution Width Predicts Increased Risk of 30-Day Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Authors:  Mengpei Zhu; Lisong Dai; Lei Wan; Shuling Zhang; Hongxing Peng
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-02-24

7.  WeChat as a Platform for Baduanjin Intervention in Patients With Stable Chronic Obstructive Pulmonary Disease in China: Retrospective Randomized Controlled Trial.

Authors:  Junjie Bi; Wei Yang; Ping Hao; Wei Zhang; Xiongbiao Wang; Yongmei Zhao; Dan Wei; Yipeng Sun; Yuhua Lin; Meng Sun; Xuan Chen; Xuming Luo; Shanqun Li
Journal:  JMIR Mhealth Uhealth       Date:  2021-02-02       Impact factor: 4.773

8.  Overcoming Therapeutic Inertia to Reduce the Risk of COPD Exacerbations: Four Action Points for Healthcare Professionals.

Authors:  Dave Singh; Steve Holmes; Claire Adams; Mona Bafadhel; John R Hurst
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-11-01

9.  Benefits Conferred by Peer-Support Nursing Intervention to Pulmonary Function and Quality of Life in Nonsmoking Patients with COPD.

Authors:  Xiaoling Yao; Xiaoyu Wang; Jing Yuan; Zhikang Huang; Dan Wu; Hongyan Xu
Journal:  Can Respir J       Date:  2021-06-15       Impact factor: 2.409

Review 10.  A Review of Clinical Trials That Contributed to Chronic Obstructive Pulmonary Disease Treatment Protocols.

Authors:  Jude ElSaygh; Anas Zaher; Pratiksha Nathani; Mohamed Omballi
Journal:  Cureus       Date:  2021-04-21
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