Tao Yang1, Chihua Chen2, Zhongyuanlong Chen3. 1. Imaging Department, Linyi Central Hospital, Linyi, 276400, Shandong, China. 2. Radiology Department, Hubei Provincial Hospital of Integrated Chinese & Western Medicine, Wuhan, 430015, Hubei, China. 3. Department of Radiology, Chest Hospital of Xinjiang Uygur Autonomous Region of the PRC, No. 106, Yan'an road, Urumqi, 830049, Xinjiang, China. gnvivp@163.com.
Abstract
BACKGROUND: It is necessary to analyze the CT pulmonary vascular parameters and disease severity in chronic obstructive pulmonary disease (COPD) patients to provide evidence support for the management of COPD. METHODS: COPD patients on acute exacerbation admitted to our hospital from COPD patients from January 2019 to March 2020 was selected. The characteristics and ratio of the cross-sectional area (CSA) of small pulmonary vessels to the total area of the lung field, and the ratio of pulmonary artery and aorta (PA/A) cross-sectional diameter in patients with COPD were analyzed. RESULTS: A total of 128 COPD patients were included. There were significant differences in the duration of COPD, smoking history, the PaO2, PaCO2, pH, and FEV1, FVC and FEV1/FVC among COPD patients with different severity (all p < 0.05). The duration of COPD, smoking, PaO2, PaCO2, CSA and PA/A were correlated with the COPD severity (all p < 0.05). Both CSA, PA/A were correlated with post BD FEV1 (all p < 0.05). The cutoff value of CSA and PA/A for the diagnosis of severe COPD was 0.61 and 0.87 respectively, and the AUC of CSA and PA/A for the diagnosis of severe COPD was 0.724 and 0.782 respectively. CONCLUSIONS: Patients with CSA ≤ 0.61 and PA/A ≥ 0.87 may have higher risks for severe COPD, and more studies are needed in the future to further elucidate the management of COPD.
BACKGROUND: It is necessary to analyze the CT pulmonary vascular parameters and disease severity in chronic obstructive pulmonary disease (COPD) patients to provide evidence support for the management of COPD. METHODS:COPDpatients on acute exacerbation admitted to our hospital from COPDpatients from January 2019 to March 2020 was selected. The characteristics and ratio of the cross-sectional area (CSA) of small pulmonary vessels to the total area of the lung field, and the ratio of pulmonary artery and aorta (PA/A) cross-sectional diameter in patients with COPD were analyzed. RESULTS: A total of 128 COPDpatients were included. There were significant differences in the duration of COPD, smoking history, the PaO2, PaCO2, pH, and FEV1, FVC and FEV1/FVC among COPDpatients with different severity (all p < 0.05). The duration of COPD, smoking, PaO2, PaCO2, CSA and PA/A were correlated with the COPD severity (all p < 0.05). Both CSA, PA/A were correlated with post BD FEV1 (all p < 0.05). The cutoff value of CSA and PA/A for the diagnosis of severe COPD was 0.61 and 0.87 respectively, and the AUC of CSA and PA/A for the diagnosis of severe COPD was 0.724 and 0.782 respectively. CONCLUSIONS:Patients with CSA ≤ 0.61 and PA/A ≥ 0.87 may have higher risks for severe COPD, and more studies are needed in the future to further elucidate the management of COPD.
Authors: Lowie Egw Vanfleteren; Bianca Beghe; Anders Andersson; Daniel Hansson; Leonardo M Fabbri; Ludger Grote Journal: Eur J Intern Med Date: 2020-01-21 Impact factor: 4.487
Authors: Atsushi Nambu; Jordan Zach; Joyce Schroeder; Gongyoung Jin; Song Soo Kim; Yu-Il Kim; Christina Schnell; Russell Bowler; David A Lynch Journal: Eur J Radiol Date: 2016-09-13 Impact factor: 3.528
Authors: Kristoffer Ostridge; Nicholas P Williams; Viktoriya Kim; Stephen Harden; Simon Bourne; Stuart C Clarke; Emmanuel Aris; Sonia Mesia-Vela; Jeanne-Marie Devaster; Andrew Tuck; Anthony Williams; Stephen Wootton; Karl J Staples; Tom M A Wilkinson Journal: Respir Res Date: 2018-02-20