OBJECTIVE: To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery. METHODS: Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatment 3D CBCT images, (3) verification orthogonal 2D kV images, (4) treatment including mid-treatment 2D kV images (for the final 15 patients only), and (5) post-treatment orthogonal 2D kV or 3D CBCT images. Patient position was corrected at each step to align the biopsy clip and to verify surrounding soft tissue positioning. RESULTS: The mean combined vector magnitude shifts and standard deviations at the 5 imaging steps were (1) 0.96 ± 0.69, (2) 0.33 ± 0.40, (3) 0.05 ± 0.12, (4) 0.15 ± 0.17, and (5) 0.27 ± 0.24 in cm. The mean total IGRT time was 40.2 ± 13.2 minutes. Each step was shortened by 2 to 5 minutes with improvements implemented. Overall, improvements in the IGRT process reduced the mean total IGRT time by approximately 20 minutes. Clip visibility was improved by implementing oblique orthogonal images. CONCLUSION: Multiple imaging steps confirmed accurate patient positioning. Appropriate planning and imaging strategies improved the effectiveness and efficiency of the IGRT process for preoperative partial breast radiosurgery.
OBJECTIVE: To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery. METHODS: Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatment 3D CBCT images, (3) verification orthogonal 2D kV images, (4) treatment including mid-treatment 2D kV images (for the final 15 patients only), and (5) post-treatment orthogonal 2D kV or 3D CBCT images. Patient position was corrected at each step to align the biopsy clip and to verify surrounding soft tissue positioning. RESULTS: The mean combined vector magnitude shifts and standard deviations at the 5 imaging steps were (1) 0.96 ± 0.69, (2) 0.33 ± 0.40, (3) 0.05 ± 0.12, (4) 0.15 ± 0.17, and (5) 0.27 ± 0.24 in cm. The mean total IGRT time was 40.2 ± 13.2 minutes. Each step was shortened by 2 to 5 minutes with improvements implemented. Overall, improvements in the IGRT process reduced the mean total IGRT time by approximately 20 minutes. Clip visibility was improved by implementing oblique orthogonal images. CONCLUSION: Multiple imaging steps confirmed accurate patient positioning. Appropriate planning and imaging strategies improved the effectiveness and efficiency of the IGRT process for preoperative partial breast radiosurgery.
Authors: Jayant S Vaidya; David J Joseph; Jeffrey S Tobias; Max Bulsara; Frederik Wenz; Christobel Saunders; Michael Alvarado; Henrik L Flyger; Samuele Massarut; Wolfgang Eiermann; Mohammed Keshtgar; John Dewar; Uta Kraus-Tiefenbacher; Marc Sütterlin; Laura Esserman; Helle M R Holtveg; Mario Roncadin; Steffi Pigorsch; Marinos Metaxas; Mary Falzon; April Matthews; Tammy Corica; Norman R Williams; Michael Baum Journal: Lancet Date: 2010-07-10 Impact factor: 79.321
Authors: Elizabeth M Nichols; Anil A Dhople; Majid M Mohiuddin; Todd W Flannery; Cedric X Yu; William F Regine Journal: Int J Radiat Oncol Biol Phys Date: 2010-05-01 Impact factor: 7.038
Authors: Umberto Veronesi; Roberto Orecchia; Alberto Luini; Viviana Galimberti; Stefano Zurrida; Mattia Intra; Paolo Veronesi; Paolo Arnone; Maria Cristina Leonardi; Mario Ciocca; Roberta Lazzari; Pietro Caldarella; Nicole Rotmensz; Claudia Sangalli; Daniele Sances; Patrick Maisonneuve Journal: Breast Cancer Res Treat Date: 2010-08-15 Impact factor: 4.872
Authors: Bradford S Hoppe; Benjamin Laser; Alex V Kowalski; Sandra C Fontenla; Elizabeth Pena-Greenberg; Ellen D Yorke; D Michael Lovelock; Margie A Hunt; Kenneth E Rosenzweig Journal: Int J Radiat Oncol Biol Phys Date: 2008-12-01 Impact factor: 7.038
Authors: James W Snider; Yildirim Mutaf; Elizabeth Nichols; Andrea Hall; Patrick Vadnais; William F Regine; Steven J Feigenberg Journal: Technol Cancer Res Treat Date: 2017-07-14