OBJECTIVE: This study aimed to determine whether different measures of habitual physical activity (PA) at baseline predict weight change, weight compensation, and changes in energy intake (EI) during a 24-week supervised aerobic exercise intervention. METHODS: Data from 108 participants (78 women; 48.7 [SD: 11.6] years; BMI 31.4 [SD: 4.6] kg/m2 ), randomly assigned to either the moderate-dose exercise group (8 kcal/kg of body weight per week) or the high-dose exercise group (20 kcal/kg of body weight per week) of the Examination of Mechanisms of Exercise-induced Weight Compensation (E-MECHANIC) trial, were analyzed. Moderate-to-vigorous PA (MVPA), steps per day, and PA energy expenditure (PAEE) were measured with SenseWear armbands (BodyMedia, Pittsburgh, Pennsylvania), and total activity energy expenditure and EI were estimated with doubly labeled water, all over 2 weeks, before and toward the end of the intervention. Multiple linear regression models, adjusted for sex, exercise group, and baseline value of the outcome, were used. RESULTS: Baseline habitual MVPA levels predicted weight change (β = -0.275; P = 0.020), weight compensation (β = -0.238; P = 0.043), and change in EI (β = -0.318; P = 0.001). Associations between baseline PAEE and outcomes were comparable, whereas steps per day and, importantly, total activity energy expenditure (via doubly labeled water) did not significantly predict change in weight-related outcomes. CONCLUSIONS: While acknowledging substantial variability in the data, on average, lower baseline habitual MVPA and PAEE levels were associated with less weight loss from exercise, higher compensation, and increased EI.
RCT Entities:
OBJECTIVE: This study aimed to determine whether different measures of habitual physical activity (PA) at baseline predict weight change, weight compensation, and changes in energy intake (EI) during a 24-week supervised aerobic exercise intervention. METHODS: Data from 108 participants (78 women; 48.7 [SD: 11.6] years; BMI 31.4 [SD: 4.6] kg/m2 ), randomly assigned to either the moderate-dose exercise group (8 kcal/kg of body weight per week) or the high-dose exercise group (20 kcal/kg of body weight per week) of the Examination of Mechanisms of Exercise-induced Weight Compensation (E-MECHANIC) trial, were analyzed. Moderate-to-vigorous PA (MVPA), steps per day, and PA energy expenditure (PAEE) were measured with SenseWear armbands (BodyMedia, Pittsburgh, Pennsylvania), and total activity energy expenditure and EI were estimated with doubly labeled water, all over 2 weeks, before and toward the end of the intervention. Multiple linear regression models, adjusted for sex, exercise group, and baseline value of the outcome, were used. RESULTS: Baseline habitual MVPA levels predicted weight change (β = -0.275; P = 0.020), weight compensation (β = -0.238; P = 0.043), and change in EI (β = -0.318; P = 0.001). Associations between baseline PAEE and outcomes were comparable, whereas steps per day and, importantly, total activity energy expenditure (via doubly labeled water) did not significantly predict change in weight-related outcomes. CONCLUSIONS: While acknowledging substantial variability in the data, on average, lower baseline habitual MVPA and PAEE levels were associated with less weight loss from exercise, higher compensation, and increased EI.
Authors: Corby K Martin; William D Johnson; Candice A Myers; John W Apolzan; Conrad P Earnest; Diana M Thomas; Jennifer C Rood; Neil M Johannsen; Catrine Tudor-Locke; Melissa Harris; Daniel S Hsia; Timothy S Church Journal: Am J Clin Nutr Date: 2019-09-01 Impact factor: 7.045
Authors: D M Thomas; C K Martin; S Lettieri; C Bredlau; K Kaiser; T Church; C Bouchard; S B Heymsfield Journal: Int J Obes (Lond) Date: 2013-04-08 Impact factor: 5.095
Authors: Candice A Myers; William D Johnson; Conrad P Earnest; Jennifer C Rood; Catrine Tudor-Locke; Neil M Johannsen; Shannon Cocreham; Melissa Harris; Timothy S Church; Corby K Martin Journal: Trials Date: 2014-06-07 Impact factor: 2.279
Authors: Casey Regan; Caitlin Fehily; Elizabeth Campbell; Jenny Bowman; Jack Faulkner; Christopher Oldmeadow; Kate Bartlem Journal: Prev Med Rep Date: 2022-06-27