PURPOSE: In this study, we sought to develop a self-navigation strategy for improving the reconstruction of diffusion weighted 3D multishot echo planar imaging (EPI). We propose a method for extracting the phase correction information from the acquisition itself, eliminating the need for a 2D navigator, further accelerating the acquisition. METHODS: In-vivo acquisitions at 3T with 0.9 mm and 1.5 mm isotropic resolutions were used to evaluate the performance of the self-navigation strategy. Sensitivity to motion was tested using a large difference in pitch position of the head. Using a multishell diffusion weighted acquisition, tractography results were obtained at (0.9 mm)3 to validate the quality with conventional acquisition. RESULTS: The use of 3D multislab EPI with self-navigation enables 3D diffusion-weighted spin echo EPI acquisitions that have the same efficiency as 2D single-shot acquisition. For matched acquisition time the image signal-to-noise ratio (SNR) between 3D and 2D acquisition is shown to be comparable for whole-brain coverage with (1.5 mm)3 resolution and for (0.9 mm)3 resolution the 3D acquisition has higher SNR than what can be obtained with 2D acquisitions using current state-of-art multiband techniques. The self-navigation technique was shown to be stable under inter-volume motion. In tractography analysis, the higher resolution afforded by our technique enabled clear delineation of the tapetum and posterior corona radiata. CONCLUSION: The proposed self-navigation approach utilized a self-consistent phase in 3D diffusion weighted acquisitions. Its efficiency and stability were demonstrated for a plurality of common acquisitions. The proposed self-navigation approach allows for faster acquisition of 3D multishot EPI desirable for large field of view and/or higher resolution.
PURPOSE: In this study, we sought to develop a self-navigation strategy for improving the reconstruction of diffusion weighted 3D multishot echo planar imaging (EPI). We propose a method for extracting the phase correction information from the acquisition itself, eliminating the need for a 2D navigator, further accelerating the acquisition. METHODS: In-vivo acquisitions at 3T with 0.9 mm and 1.5 mm isotropic resolutions were used to evaluate the performance of the self-navigation strategy. Sensitivity to motion was tested using a large difference in pitch position of the head. Using a multishell diffusion weighted acquisition, tractography results were obtained at (0.9 mm)3 to validate the quality with conventional acquisition. RESULTS: The use of 3D multislab EPI with self-navigation enables 3D diffusion-weighted spin echo EPI acquisitions that have the same efficiency as 2D single-shot acquisition. For matched acquisition time the image signal-to-noise ratio (SNR) between 3D and 2D acquisition is shown to be comparable for whole-brain coverage with (1.5 mm)3 resolution and for (0.9 mm)3 resolution the 3D acquisition has higher SNR than what can be obtained with 2D acquisitions using current state-of-art multiband techniques. The self-navigation technique was shown to be stable under inter-volume motion. In tractography analysis, the higher resolution afforded by our technique enabled clear delineation of the tapetum and posterior corona radiata. CONCLUSION: The proposed self-navigation approach utilized a self-consistent phase in 3D diffusion weighted acquisitions. Its efficiency and stability were demonstrated for a plurality of common acquisitions. The proposed self-navigation approach allows for faster acquisition of 3D multishot EPI desirable for large field of view and/or higher resolution.
Authors: K Setsompop; R Kimmlingen; E Eberlein; T Witzel; J Cohen-Adad; J A McNab; B Keil; M D Tisdall; P Hoecht; P Dietz; S F Cauley; V Tountcheva; V Matschl; V H Lenz; K Heberlein; A Potthast; H Thein; J Van Horn; A Toga; F Schmitt; D Lehne; B R Rosen; V Wedeen; L L Wald Journal: Neuroimage Date: 2013-05-24 Impact factor: 6.556
Authors: Kawin Setsompop; Borjan A Gagoski; Jonathan R Polimeni; Thomas Witzel; Van J Wedeen; Lawrence L Wald Journal: Magn Reson Med Date: 2011-08-19 Impact factor: 4.668
Authors: Bastien Guérin; Kawin Setsompop; Huihui Ye; Benedikt A Poser; Andrew V Stenger; Lawrence L Wald Journal: Magn Reson Med Date: 2014-06-17 Impact factor: 4.668
Authors: David C Van Essen; Stephen M Smith; Deanna M Barch; Timothy E J Behrens; Essa Yacoub; Kamil Ugurbil Journal: Neuroimage Date: 2013-05-16 Impact factor: 6.556
Authors: Michael P Harms; Leah H Somerville; Beau M Ances; Jesper Andersson; Deanna M Barch; Matteo Bastiani; Susan Y Bookheimer; Timothy B Brown; Randy L Buckner; Gregory C Burgess; Timothy S Coalson; Michael A Chappell; Mirella Dapretto; Gwenaëlle Douaud; Bruce Fischl; Matthew F Glasser; Douglas N Greve; Cynthia Hodge; Keith W Jamison; Saad Jbabdi; Sridhar Kandala; Xiufeng Li; Ross W Mair; Silvia Mangia; Daniel Marcus; Daniele Mascali; Steen Moeller; Thomas E Nichols; Emma C Robinson; David H Salat; Stephen M Smith; Stamatios N Sotiropoulos; Melissa Terpstra; Kathleen M Thomas; M Dylan Tisdall; Kamil Ugurbil; Andre van der Kouwe; Roger P Woods; Lilla Zöllei; David C Van Essen; Essa Yacoub Journal: Neuroimage Date: 2018-09-24 Impact factor: 6.556