Cem Karaali1, Mustafa Emiroglu2, Sabri Atalay3, Ismail Sert4, Ayberk Dursun5, Sukran Kose6, Gokhan Akbulut7, Cengiz Aydın8. 1. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. cemkaraali@gmail.com. 2. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. musemiroglu@gmail.com. 3. Department of Infectious Diseases, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. drsatalay@yahoo.com. 4. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. drismailsertege@yahoo.com. 5. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. dursunayberk845@gmail.com. 6. Department of Infectious Diseases, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. sukrankose@yahoo.com. 7. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. gnakbulut@gmail.com. 8. Department of General Surgery, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey. caydin2@yahoo.com.
Abstract
INTRODUCTION: This study aims to evaluate the efficacy of a new antimicrobial stewardship program (ASP) on surgical antibiotic prophylaxis (SP) and antibiotics in discharge prescriptions used as a continuation of SP. METHODOLOGY: The study included elective patients with clean and clean-contaminated wounds. The accuracy of the assigned SP was evaluated according to international guidelines. Primary outcome measures comprised appropriateness of prophylactic antibiotic indication, correct timing of initial dose, discontinuation of SP within 24 hours, and antibiotic prescription at discharge. A secondary outcome measure was to determine whether the effect of ASP was sustained long-term. RESULTS: The total compliance rate for all stages of SP increased from 8% to 52.1% after the intervention (p < 0.05). When analyzed according to individual SP components, it was found that although ASP did not change first dose timing rates, it did affect the rates of prophylactic antibiotic indication, discontinuation of SP within 24 hours and antibiotic prescription at discharge, with statistical significance (p < 0.05). In addition, ASP continued to increase its effectiveness throughout the 3rd year. CONCLUSIONS: Based on the findings of our study, it seems clear that the modified ASP introduced in our general surgery clinic can be used effectively and simply; in addition, this ASP increases its efficacy with time. Copyright (c) 2019 Cem Karaali, Mustafa Emiroglu, Sabri Atalay, Ismail Sert, Ayberk Dursun, Sukran Kose, Gokhan Akbulut, Cengiz Aydin.
INTRODUCTION: This study aims to evaluate the efficacy of a new antimicrobial stewardship program (ASP) on surgical antibiotic prophylaxis (SP) and antibiotics in discharge prescriptions used as a continuation of SP. METHODOLOGY: The study included elective patients with clean and clean-contaminated wounds. The accuracy of the assigned SP was evaluated according to international guidelines. Primary outcome measures comprised appropriateness of prophylactic antibiotic indication, correct timing of initial dose, discontinuation of SP within 24 hours, and antibiotic prescription at discharge. A secondary outcome measure was to determine whether the effect of ASP was sustained long-term. RESULTS: The total compliance rate for all stages of SP increased from 8% to 52.1% after the intervention (p < 0.05). When analyzed according to individual SP components, it was found that although ASP did not change first dose timing rates, it did affect the rates of prophylactic antibiotic indication, discontinuation of SP within 24 hours and antibiotic prescription at discharge, with statistical significance (p < 0.05). In addition, ASP continued to increase its effectiveness throughout the 3rd year. CONCLUSIONS: Based on the findings of our study, it seems clear that the modified ASP introduced in our general surgery clinic can be used effectively and simply; in addition, this ASP increases its efficacy with time. Copyright (c) 2019 Cem Karaali, Mustafa Emiroglu, Sabri Atalay, Ismail Sert, Ayberk Dursun, Sukran Kose, Gokhan Akbulut, Cengiz Aydin.
Authors: Julius C Mwita; Olayinka O Ogunleye; Adesola Olalekan; Aubrey C Kalungia; Amanj Kurdi; Zikria Saleem; Jacqueline Sneddon; Brian Godman Journal: Int J Gen Med Date: 2021-02-18
Authors: Lesley Cooper; Jacqueline Sneddon; Daniel Kwame Afriyie; Israel A Sefah; Amanj Kurdi; Brian Godman; R Andrew Seaton Journal: JAC Antimicrob Resist Date: 2020-10-05