Literature DB >> 32035026

Codon Modification and PAMPs in Clinical AAV Vectors: The Tortoise or the Hare?

J Fraser Wright1.   

Abstract

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Year:  2020        PMID： 32035026      PMCID： PMC7054817          DOI： 10.1016/j.ymthe.2020.01.026

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  14 in total

Review 1.  Codon bias and heterologous protein expression.

Authors:  Claes Gustafsson; Sridhar Govindarajan; Jeremy Minshull
Journal:  Trends Biotechnol       Date:  2004-07       Impact factor: 19.536

2.  CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.

Authors:  G Hartmann; G J Weiner; A M Krieg
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

Review 3.  CpG DNA as a vaccine adjuvant.

Authors:  Christian Bode; Gan Zhao; Folkert Steinhagen; Takeshi Kinjo; Dennis M Klinman
Journal:  Expert Rev Vaccines       Date:  2011-04       Impact factor: 5.217

4.  Rescue of the adeno-associated virus genome from a plasmid vector: evidence for rescue by replication.

Authors:  Peter Ward; Per Elias; R Michael Linden
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103

5.  Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T Cells.

Authors:  Jamie L Shirley; Geoffrey D Keeler; Alexandra Sherman; Irene Zolotukhin; David M Markusic; Brad E Hoffman; Laurence M Morel; Mark A Wallet; Cox Terhorst; Roland W Herzog
Journal:  Mol Ther       Date:  2019-11-15       Impact factor: 11.454

6.  The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice.

Authors:  Jiangao Zhu; Xiaopei Huang; Yiping Yang
Journal:  J Clin Invest       Date:  2009-07-01       Impact factor: 14.808

7.  Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.

Authors:  Catherine S Manno; Glenn F Pierce; Valder R Arruda; Bertil Glader; Margaret Ragni; John J Rasko; John Rasko; Margareth C Ozelo; Keith Hoots; Philip Blatt; Barbara Konkle; Michael Dake; Robin Kaye; Mahmood Razavi; Albert Zajko; James Zehnder; Pradip K Rustagi; Hiroyuki Nakai; Amy Chew; Debra Leonard; J Fraser Wright; Ruth R Lessard; Jürg M Sommer; Michael Tigges; Denise Sabatino; Alvin Luk; Haiyan Jiang; Federico Mingozzi; Linda Couto; Hildegund C Ertl; Katherine A High; Mark A Kay
Journal:  Nat Med       Date:  2006-02-12       Impact factor: 53.440

8.  The Effect of CpG Sequences on Capsid-Specific CD8+ T Cell Responses to AAV Vector Gene Transfer.

Authors:  ZhiQuan Xiang; Raj K Kurupati; Yan Li; Klaudia Kuranda; Xiangyang Zhou; Federico Mingozzi; Katherine A High; Hildegund C J Ertl
Journal:  Mol Ther       Date:  2019-11-21       Impact factor: 11.454

9.  Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression.

Authors:  Stephan Fath; Asli Petra Bauer; Michael Liss; Anne Spriestersbach; Barbara Maertens; Peter Hahn; Christine Ludwig; Frank Schäfer; Marcus Graf; Ralf Wagner
Journal:  PLoS One       Date:  2011-03-03       Impact factor: 3.240

10.  Signatures of DNA Methylation across Insects Suggest Reduced DNA Methylation Levels in Holometabola.

Authors:  Panagiotis Provataris; Karen Meusemann; Oliver Niehuis; Sonja Grath; Bernhard Misof
Journal:  Genome Biol Evol       Date:  2018-04-01       Impact factor: 3.416
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  20 in total

Review 1.  Quantification of CpG Motifs in rAAV Genomes: Avoiding the Toll.

Authors:  J Fraser Wright
Journal:  Mol Ther       Date:  2020-07-14       Impact factor: 11.454

2.  BAX 335 hemophilia B gene therapy clinical trial results: potential impact of CpG sequences on gene expression.

Authors:  Barbara A Konkle; Christopher E Walsh; Miguel A Escobar; Neil C Josephson; Guy Young; Annette von Drygalski; Scott W J McPhee; R Jude Samulski; Ivan Bilic; Maurus de la Rosa; Birgit M Reipert; Hanspeter Rottensteiner; Friedrich Scheiflinger; John C Chapin; Bruce Ewenstein; Paul E Monahan
Journal:  Blood       Date:  2021-02-11       Impact factor: 22.113

Review 3.  Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders.

Authors:  Beverly L Davidson; Guangping Gao; Elizabeth Berry-Kravis; Allison M Bradbury; Carsten Bönnemann; Joseph D Buxbaum; Gavin R Corcoran; Steven J Gray; Heather Gray-Edwards; Robin J Kleiman; Adam J Shaywitz; Dan Wang; Huda Y Zoghbi; Terence R Flotte; Sitra Tauscher-Wisniewski; Cynthia J Tifft; Mustafa Sahin
Journal:  Mol Ther       Date:  2022-05-17       Impact factor: 12.910

Review 4.  Gene Therapy for Acquired and Genetic Cholestasis.

Authors:  Javier Martínez-García; Angie Molina; Gloria González-Aseguinolaza; Nicholas D Weber; Cristian Smerdou
Journal:  Biomedicines       Date:  2022-05-26

5.  Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.

Authors:  Ngoc Tam Tran; Emilie Lecomte; Sylvie Saleun; Suk Namkung; Cécile Robin; Kristina Weber; Eric Devine; Veronique Blouin; Oumeya Adjali; Eduard Ayuso; Guangping Gao; Magalie Penaud-Budloo; Phillip W L Tai
Journal:  Hum Gene Ther       Date:  2022-04       Impact factor: 4.793

Review 6.  Durability of transgene expression after rAAV gene therapy.

Authors:  Manish Muhuri; Daniel I Levy; Martin Schulz; Douglas McCarty; Guangping Gao
Journal:  Mol Ther       Date:  2022-03-10       Impact factor: 12.910

7.  Challenges Posed by Immune Responses to AAV Vectors: Addressing Root Causes.

Authors:  Bradley A Hamilton; J Fraser Wright
Journal:  Front Immunol       Date:  2021-05-17       Impact factor: 7.561

8.  "D" matters in recombinant AAV DNA packaging.

Authors:  Junping Zhang; Ping Guo; Yinxia Xu; Patrick L Mulcrone; R Jude Samulski; Weidong Xiao
Journal:  Mol Ther       Date:  2021-05-19       Impact factor: 12.910

Review 9.  Overcoming innate immune barriers that impede AAV gene therapy vectors.

Authors:  Manish Muhuri; Yukiko Maeda; Hong Ma; Sanjay Ram; Katherine A Fitzgerald; Phillip Wl Tai; Guangping Gao
Journal:  J Clin Invest       Date:  2021-01-04       Impact factor: 14.808

10.  Effect of CpG Depletion of Vector Genome on CD8+ T Cell Responses in AAV Gene Therapy.

Authors:  Thais B Bertolini; Jamie L Shirley; Irene Zolotukhin; Xin Li; Tsuneyasu Kaisho; Weidong Xiao; Sandeep R P Kumar; Roland W Herzog
Journal:  Front Immunol       Date:  2021-05-31       Impact factor: 7.561
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