Literature DB >> 3201016

A stochastic two-stage model for cancer risk assessment. I. The hazard function and the probability of tumor.

S H Moolgavkar1, A Dewanji, D J Venzon.   

Abstract

We present a mathematical treatment of a two-mutation model for carcinogenesis with time-dependent parameters. This model has previously been shown to be consistent with epidemiologic and experimental data. An approximate hazard function used in previous papers is critically evaluated.

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Year:  1988        PMID： 3201016     DOI： 10.1111/j.1539-6924.1988.tb00502.x

Source DB:  PubMed          Journal:  Risk Anal        ISSN： 0272-4332            Impact factor:   4.000


  35 in total

1.  Radon-induced lung cancer in French and Czech miner cohorts described with a two-mutation cancer model.

Authors:  Marco J P Brugmans; Sietse M Rispens; Harmen Bijwaard; Dominique Laurier; Agnes Rogel; Ladislav Tomásek; Margot Tirmarche
Journal:  Radiat Environ Biophys       Date:  2004-08-17       Impact factor: 1.925

2.  Breast cancer risk in atomic bomb survivors from multi-model inference with incidence data 1958-1998.

Authors:  J C Kaiser; P Jacob; R Meckbach; H M Cullings
Journal:  Radiat Environ Biophys       Date:  2011-09-23       Impact factor: 1.925

3.  Computational modeling of signaling pathways mediating cell cycle checkpoint control and apoptotic responses to ionizing radiation-induced DNA damage.

Authors:  Yuchao Zhao; In Chio Lou; Rory B Conolly
Journal:  Dose Response       Date:  2011-10-25       Impact factor: 2.658

4.  Breast cancer risk from different mammography screening practices.

Authors:  Harmen Bijwaard; Alina Brenner; Fieke Dekkers; Teun van Dillen; Charles E Land; John D Boice
Journal:  Radiat Res       Date:  2010-09       Impact factor: 2.841

Review 5.  Systems biology and its potential role in radiobiology.

Authors:  Ludwig Feinendegen; Philip Hahnfeldt; Eric E Schadt; Michael Stumpf; Eberhard O Voit
Journal:  Radiat Environ Biophys       Date:  2007-12-18       Impact factor: 1.925

6.  Evaluation of screening strategies for pre-malignant lesions using a biomathematical approach.

Authors:  Jihyoun Jeon; Rafael Meza; Suresh H Moolgavkar; E Georg Luebeck
Journal:  Math Biosci       Date:  2008-02-26       Impact factor: 2.144

7.  Multistage carcinogenesis and the incidence of colorectal cancer.

Authors:  E Georg Luebeck; Suresh H Moolgavkar
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-01       Impact factor: 11.205

8.  Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: identification of key issues.

Authors:  Ravi P Subramaniam; Chao Chen; Kenny S Crump; Danielle Devoney; John F Fox; Christopher J Portier; Paul M Schlosser; Chad M Thompson; Paul White
Journal:  Risk Anal       Date:  2008-06-28       Impact factor: 4.000

Review 9.  Cancer models, genomic instability and somatic cellular Darwinian evolution.

Authors:  Mark P Little
Journal:  Biol Direct       Date:  2010-04-20       Impact factor: 4.540

Review 10.  What role for biologically based dose-response models in estimating low-dose risk?

Authors:  Kenny S Crump; Chao Chen; Weihsueh A Chiu; Thomas A Louis; Christopher J Portier; Ravi P Subramaniam; Paul D White
Journal:  Environ Health Perspect       Date:  2010-01-04       Impact factor: 9.031
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