Asimina Mataftsi1, Maria Dermenoudi2, Artemis Matsou2, Argyrios Tzamalis2, Periklis Brazitikos2, Persefoni Talimtzi3, Nikolaos Ziakas2, Ioannis T Tsinopoulos2. 1. Department of Ophthalmology, Aristotle University of Thessaloniki, 56403, Thessaloniki, Greece. amatafts@auth.gr. 2. Department of Ophthalmology, Aristotle University of Thessaloniki, 56403, Thessaloniki, Greece. 3. Department of Hygiene, Social-Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Abstract
PURPOSE: To compare safety of wound hydration to anterior chamber air tamponade for securing watertight closure of clear corneal incisions, during uneventful cataract surgery. METHODS: Prospective, comparative case-control series. Patients undergoing phacoemulsification were assigned to receive either anterior chamber air bubble (Group A) or intrastromal wound hydration with balanced salt solution (Group B) at the end of the procedure. Two high-volume surgeons operated equal number of cases in each group employing identical surgical technique, except for corneal side incision management. Patients were assessed pre- and postoperatively at day 1, day 4, day 9, and day 30 after surgery. RESULTS:One hundred eyes of 100 patients were enrolled, of which 2 were lost to follow-up. The two groups were comparable in terms of preoperative risk factor assessment, baseline central corneal thickness (CCT), preoperative endothelial cell density, as well as cumulative dissipated energy and duration of phacoemulsification (p > 0.05). Mean CCT and best-corrected visual acuity were better in Group B on the first postoperative day, but did not differ between the two groups at all other timepoints. Surgically induced astigmatism was comparable in the two groups (p > 0.05). Endothelial cell density loss at 1 month postoperatively was greater in Group A (34.06%) compared to Group B (16.45%). CONCLUSIONS: Wound sealing with intrastromal hydration proved to be safer than air tamponade in terms of preserving endothelial cell density and function.
RCT Entities:
PURPOSE: To compare safety of wound hydration to anterior chamber air tamponade for securing watertight closure of clear corneal incisions, during uneventful cataract surgery. METHODS: Prospective, comparative case-control series. Patients undergoing phacoemulsification were assigned to receive either anterior chamber air bubble (Group A) or intrastromal wound hydration with balanced salt solution (Group B) at the end of the procedure. Two high-volume surgeons operated equal number of cases in each group employing identical surgical technique, except for corneal side incision management. Patients were assessed pre- and postoperatively at day 1, day 4, day 9, and day 30 after surgery. RESULTS: One hundred eyes of 100 patients were enrolled, of which 2 were lost to follow-up. The two groups were comparable in terms of preoperative risk factor assessment, baseline central corneal thickness (CCT), preoperative endothelial cell density, as well as cumulative dissipated energy and duration of phacoemulsification (p > 0.05). Mean CCT and best-corrected visual acuity were better in Group B on the first postoperative day, but did not differ between the two groups at all other timepoints. Surgically induced astigmatism was comparable in the two groups (p > 0.05). Endothelial cell density loss at 1 month postoperatively was greater in Group A (34.06%) compared to Group B (16.45%). CONCLUSIONS: Wound sealing with intrastromal hydration proved to be safer than air tamponade in terms of preserving endothelial cell density and function.
Entities:
Keywords:
Air tamponade; Cataract surgery; Corneal wound hydration; Phacoemulsification
Authors: Ioannis T Tsinopoulos; Lampros P Lamprogiannis; Konstantinos T Tsaousis; Asimina Mataftsi; Chrysanthos Symeonidis; Nikolaos T Chalvatzis; Stavros A Dimitrakos Journal: Clin Ophthalmol Date: 2013-05-16
Authors: Young Min Park; Jong Soo Lee; Ji Eun Lee; Yeon Ji Jo; Ik Soo Byon; Sung Who Park Journal: Int J Ophthalmol Date: 2022-03-18 Impact factor: 1.779