Ruth Chan1,2,3, Jason Leung4, Nelson Tang5, Jean Woo6,7,8. 1. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China. ruthchansm@cuhk.edu.hk. 2. Centre for Nutritional Studies, The Chinese University of Hong Kong, Hong Kong SAR, China. ruthchansm@cuhk.edu.hk. 3. Department of Medicine and Therapeutics, 9/F Clinical Sciences Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China. ruthchansm@cuhk.edu.hk. 4. Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong SAR, China. 5. Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China. 6. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China. 7. Centre for Nutritional Studies, The Chinese University of Hong Kong, Hong Kong SAR, China. 8. Jockey Club Institute of Ageing, The Chinese University of Hong Kong, Hong Kong SAR, China.
Abstract
PURPOSE: Environmental and lifestyle factors that affect oxidative stress and inflammation may influence telomere length (TL). There are limited data to relate dietary patterns with TL. This study examined the association of various dietary patterns with TL in Chinese older adults. METHODS: We conducted a cross-sectional analysis and performed multivariate linear regression analyses using available data from 1981 (965 men, 1016 women) community-dwelling Chinese adults aged 65 years and over in Hong Kong. The interviewer administered questionnaires that covered dietary intake estimation and dietary pattern generation from the food frequency questionnaire, demographic and lifestyle factors, and self-reported medical history. TL was measured by quantitative real-time polymerase chain reaction. RESULTS: None of the dietary pattern scores including the Diet Quality Index-International (DQI-I) score, the Dietary Approaches to Stop Hypertension (DASH) score, the Mediterranean-DASH Intervention for Neurodegenerative Delay Diet (MIND) score, the Mediterranean Diet Score (MDS), the Okinawan diet score, as well as the "vegetables-fruits" pattern score, the "snacks-drinks-milk" pattern score, and the "meat-fish" pattern score were associated with TL in the age- and sex-adjusted model and the multivariate adjusted model. CONCLUSION: Our findings suggest a minimal role of dietary patterns in telomere length in community-dwelling Chinese older adults.
PURPOSE: Environmental and lifestyle factors that affect oxidative stress and inflammation may influence telomere length (TL). There are limited data to relate dietary patterns with TL. This study examined the association of various dietary patterns with TL in Chinese older adults. METHODS: We conducted a cross-sectional analysis and performed multivariate linear regression analyses using available data from 1981 (965 men, 1016 women) community-dwelling Chinese adults aged 65 years and over in Hong Kong. The interviewer administered questionnaires that covered dietary intake estimation and dietary pattern generation from the food frequency questionnaire, demographic and lifestyle factors, and self-reported medical history. TL was measured by quantitative real-time polymerase chain reaction. RESULTS: None of the dietary pattern scores including the Diet Quality Index-International (DQI-I) score, the Dietary Approaches to Stop Hypertension (DASH) score, the Mediterranean-DASH Intervention for Neurodegenerative Delay Diet (MIND) score, the Mediterranean Diet Score (MDS), the Okinawan diet score, as well as the "vegetables-fruits" pattern score, the "snacks-drinks-milk" pattern score, and the "meat-fish" pattern score were associated with TL in the age- and sex-adjusted model and the multivariate adjusted model. CONCLUSION: Our findings suggest a minimal role of dietary patterns in telomere length in community-dwelling Chinese older adults.
Authors: Diego A Forero; Yeimy González-Giraldo; Catalina López-Quintero; Luis J Castro-Vega; George E Barreto; George Perry Journal: J Gerontol A Biol Sci Med Sci Date: 2016-04-18 Impact factor: 6.053
Authors: Marta Crous-Bou; Teresa T Fung; Jennifer Prescott; Bettina Julin; Mengmeng Du; Qi Sun; Kathryn M Rexrode; Frank B Hu; Immaculata De Vivo Journal: BMJ Date: 2014-12-02
Authors: Kenneth Lo; Andrea J Glenn; Suey Yeung; Cyril W C Kendall; John L Sievenpiper; David J A Jenkins; Jean Woo Journal: Nutrients Date: 2021-12-03 Impact factor: 5.717