Literature DB >> 16912107

Telomeres and human somatic fitness.

Abraham Aviv1.   

Abstract

Mean leukocyte telomere length may be an indicator of biological age, and as such it appears to provide information over and above chronological age of the risk for developing diseases of aging in humans. Here I propose that the mean leukocyte telomere length is an index of "somatic fitness," a concept that breaks down the artificial boundary between aging and diseases of aging. I also propose that, in exceptionally old humans, ultrashort leukocyte telomeres might be a determinant of life span.

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Year:  2006        PMID： 16912107     DOI： 10.1093/gerona/61.8.871

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN： 1079-5006            Impact factor:   6.053


  47 in total

1.  Leukocyte telomere length and mortality in the Cardiovascular Health Study.

Authors:  Annette L Fitzpatrick; Richard A Kronmal; Masayuki Kimura; Jeffrey P Gardner; Bruce M Psaty; Nancy S Jenny; Russell P Tracy; Sheetal Hardikar; Abraham Aviv
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2011-02-02       Impact factor: 6.053

2.  Discrimination and Telomere Length Among Older Adults in the United States.

Authors:  Sze Yan Liu; Ichiro Kawachi
Journal:  Public Health Rep       Date:  2017-02-01       Impact factor: 2.792

Review 3.  Epidemiologic evidence for a role of telomere dysfunction in cancer etiology.

Authors:  Jennifer Prescott; Ingrid M Wentzensen; Sharon A Savage; Immaculata De Vivo
Journal:  Mutat Res       Date:  2011-07-02       Impact factor: 2.433

4.  A year of excellence in geriatric research and some new dishes on the menu.

Authors:  Luigi Ferrucci
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2007-05       Impact factor: 6.053

5.  Telomere length and telomerase activity; a Yin and Yang of cell senescence.

Authors:  Mary Derasmo Axelrad; Temuri Budagov; Gil Atzmon
Journal:  J Vis Exp       Date:  2013-05-22       Impact factor: 1.355

6.  Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women.

Authors:  J Brent Richards; Ana M Valdes; Jeffrey P Gardner; Dimitri Paximadas; Masayuki Kimura; Ayrun Nessa; Xiaobin Lu; Gabriela L Surdulescu; Rami Swaminathan; Tim D Spector; Abraham Aviv
Journal:  Am J Clin Nutr       Date:  2007-11       Impact factor: 7.045

7.  Telomere Length is a Susceptibility Marker for Tasmanian Devil Facial Tumor Disease.

Authors:  Lane E Smith; Menna E Jones; Rodrigo Hamede; Rosana Risques; Austin H Patton; Patrick A Carter; Andrew Storfer
Journal:  Ecohealth       Date:  2020-10-30       Impact factor: 3.184

8.  Telomere length reflects phenotypic quality and costs of reproduction in a long-lived seabird.

Authors:  Christina Bauch; Peter H Becker; Simon Verhulst
Journal:  Proc Biol Sci       Date:  2012-12-05       Impact factor: 5.349

9.  Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study.

Authors:  Christopher J O'Donnell; Serkalem Demissie; Masayuki Kimura; Daniel Levy; Jeffery P Gardner; Charles White; Ralph B D'Agostino; Philip A Wolf; Joseph Polak; L Adrienne Cupples; Abraham Aviv
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-04-03       Impact factor: 8.311

10.  Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study.

Authors:  Abraham Aviv; Wei Chen; Jeffrey P Gardner; Masayuki Kimura; Michael Brimacombe; Xiaojian Cao; Sathanur R Srinivasan; Gerald S Berenson
Journal:  Am J Epidemiol       Date:  2008-12-04       Impact factor: 4.897
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