Literature DB >> 31863453

Ageing, sex, and cardioprotection.

Marisol Ruiz-Meana1,2, Kerstin Boengler3, David Garcia-Dorado1,2, Derek J Hausenloy4,5,6,7,8,9, Tuuli Kaambre10, Georgios Kararigas11,12, Cinzia Perrino13, Rainer Schulz3, Kirsti Ytrehus14.   

Abstract

Translation of cardioprotective interventions aimed at reducing myocardial injury during ischaemia-reperfusion from experimental studies to clinical practice is an important yet unmet need in cardiovascular medicine. One particular challenge facing translation is the existence of demographic and clinical factors that influence the pathophysiology of ischaemia-reperfusion injury of the heart and the effects of treatments aimed at preventing it. Among these factors, age and sex are prominent and have a recognised role in the susceptibility and outcome of ischaemic heart disease. Remarkably, some of the most powerful cardioprotective strategies proven to be effective in young animals become ineffective during ageing. This article reviews the mechanisms and implications of the modulatory effects of ageing and sex on myocardial ischaemia-reperfusion injury and their potential effects on cardioprotective interventions. LINKED ARTICLES: This article is part of a themed issue on Risk factors, comorbidities, and comedications in cardioprotection. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.23/issuetoc.
© 2019 The British Pharmacological Society.

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Year:  2020        PMID： 31863453      PMCID： PMC7680010          DOI： 10.1111/bph.14951

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  156 in total

1.  Isoflurane modulates cardiac mitochondrial bioenergetics by selectively attenuating respiratory complexes.

Authors:  Bhawana Agarwal; Ranjan K Dash; David F Stowe; Zeljko J Bosnjak; Amadou K S Camara
Journal:  Biochim Biophys Acta       Date:  2013-12-17

2.  Ryanodine Receptor Glycation Favors Mitochondrial Damage in the Senescent Heart.

Authors:  Marisol Ruiz-Meana; Marta Minguet; Diana Bou-Teen; Elisabet Miro-Casas; Celia Castans; Jose Castellano; Elena Bonzon-Kulichenko; Alberto Igual; Rafael Rodriguez-Lecoq; Jesús Vázquez; David Garcia-Dorado
Journal:  Circulation       Date:  2019-02-12       Impact factor: 29.690

Review 3.  Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart.

Authors:  JoAnn Trial; Mark L Entman; Katarzyna A Cieslik
Journal:  J Mol Cell Cardiol       Date:  2015-12-22       Impact factor: 5.000

Review 4.  Estrogen receptor activation and cardioprotection in ischemia reperfusion injury.

Authors:  Anne M Deschamps; Elizabeth Murphy; Junhui Sun
Journal:  Trends Cardiovasc Med       Date:  2010-04       Impact factor: 6.677

Review 5.  The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury.

Authors:  Sang-Bing Ong; Parisa Samangouei; Siavash Beikoghli Kalkhoran; Derek J Hausenloy
Journal:  J Mol Cell Cardiol       Date:  2014-11-14       Impact factor: 5.000

6.  Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females.

Authors:  Claudia J Lagranha; Anne Deschamps; Angel Aponte; Charles Steenbergen; Elizabeth Murphy
Journal:  Circ Res       Date:  2010-04-22       Impact factor: 17.367

Review 7.  Aging and cardioprotection.

Authors:  Arshad Jahangir; Sandeep Sagar; Andre Terzic
Journal:  J Appl Physiol (1985)       Date:  2007-08-23

8.  Postconditioning cardioprotection against infarct size and post-ischemic systolic dysfunction is influenced by gender.

Authors:  Claudia Penna; Francesca Tullio; Annalisa Merlino; Francesca Moro; Stefania Raimondo; Raffaella Rastaldo; Maria-Giulia Perrelli; Daniele Mancardi; Pasquale Pagliaro
Journal:  Basic Res Cardiol       Date:  2008-11-22       Impact factor: 17.165

Review 9.  The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Disease 2010 study.

Authors:  Andrew E Moran; Mohammad H Forouzanfar; Gregory A Roth; George A Mensah; Majid Ezzati; Abraham Flaxman; Christopher J L Murray; Mohsen Naghavi
Journal:  Circulation       Date:  2014-02-26       Impact factor: 29.690

Review 10.  The role of hexokinase in cardioprotection - mechanism and potential for translation.

Authors:  Andrew P Halestrap; Gonçalo C Pereira; Philippe Pasdois
Journal:  Br J Pharmacol       Date:  2014-11-24       Impact factor: 8.739
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  12 in total

1.  Risk factors, co-morbidities, and co-medications in cardioprotection: Importance for translation.

Authors:  Rainer Schulz; Ioanna Andreadou; Derek J Hausenloy; Péter Ferdinandy
Journal:  Br J Pharmacol       Date:  2020-12       Impact factor: 8.739

Review 2.  Ageing, sex, and cardioprotection.

Authors:  Marisol Ruiz-Meana; Kerstin Boengler; David Garcia-Dorado; Derek J Hausenloy; Tuuli Kaambre; Georgios Kararigas; Cinzia Perrino; Rainer Schulz; Kirsti Ytrehus
Journal:  Br J Pharmacol       Date:  2020-02-03       Impact factor: 8.739

Review 3.  Exploring the Food and Drug Administration's review and approval of Entresto (sacubitril/valsartan).

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Review 4.  Extracellular Vesicles in Comorbidities Associated with Ischaemic Heart Disease: Focus on Sex, an Overlooked Factor.

Authors:  Claudia Penna; Saveria Femminò; Giuseppe Alloatti; Maria F Brizzi; Tommaso Angelone; Pasquale Pagliaro
Journal:  J Clin Med       Date:  2021-01-17       Impact factor: 4.241

5.  Myocardial Ischemia-Reperfusion and Diabetes: Lessons Learned From Bedside to Bench.

Authors:  Maya Dia; Alexandre Paccalet; Bruno Pillot; Christelle Leon; Michel Ovize; Claire Crola Da Silva; Thomas Bochaton; Melanie Paillard
Journal:  Front Cardiovasc Med       Date:  2021-03-26

6.  Impact of Maturation on Myocardial Response to Ischemia and the Effectiveness of Remote Preconditioning in Male Rats.

Authors:  Lucia Kindernay; Veronika Farkasova; Jan Neckar; Jaroslav Hrdlicka; Kirsti Ytrehus; Tanya Ravingerova
Journal:  Int J Mol Sci       Date:  2021-10-12       Impact factor: 5.923

7.  Lepidium meyenii (maca) and soy isoflavones reduce cardiac stunning of ischemia-reperfusion in rats by mitochondrial mechanisms.

Authors:  Germán A Colareda; Soledad I Matera; Matías Bayley; María Inés Ragone; María Luján Flores; Osvaldo León Córdoba; Alicia E Consolini
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Review 8.  Oestrogenic Regulation of Mitochondrial Dynamics.

Authors:  Siavash Beikoghli Kalkhoran; Georgios Kararigas
Journal:  Int J Mol Sci       Date:  2022-01-20       Impact factor: 5.923

Review 9.  Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart.

Authors:  Cinzia Perrino; Péter Ferdinandy; Hans E Bøtker; Bianca J J M Brundel; Peter Collins; Sean M Davidson; Hester M den Ruijter; Felix B Engel; Eva Gerdts; Henrique Girao; Mariann Gyöngyösi; Derek J Hausenloy; Sandrine Lecour; Rosalinda Madonna; Michael Marber; Elizabeth Murphy; Maurizio Pesce; Vera Regitz-Zagrosek; Joost P G Sluijter; Sabine Steffens; Can Gollmann-Tepeköylü; Linda W Van Laake; Sophie Van Linthout; Rainer Schulz; Kirsti Ytrehus
Journal:  Cardiovasc Res       Date:  2021-01-21       Impact factor: 10.787

10.  AMPK Activation Is Indispensable for the Protective Effects of Caloric Restriction on Left Ventricular Function in Postinfarct Myocardium.

Authors:  Bernd Niemann; Ruping Pan; Hassan Issa; Andreas Simm; Rainer Schulz; Susanne Rohrbach
Journal:  Biology (Basel)       Date:  2022-03-16
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