75-degree non-mydriatic single-volume optical coherence tomographic angiography.

Optical coherence tomography (OCT) and OCT angiography (OCTA) enable three-dimensional, high-resolution imaging of the eye. Yet, while they provide unprecedented structural and angiographic imaging detail, both have only limited fields of view in comparison to other imaging modalities like fundus photography. In this paper, we present a high-speed, high-sensitivity, swept source laser-based system that can acquire non-mydriatic 75-degree field of view OCT and OCTA images in a single complete scan without resorting to montaging techniques. The system uses an optimized scanning protocol and achieves capillary-level image quality. Such data may improve early detection of pathology and provide valuable information during disease monitoring.