M Heald1, D Adams2,3, C Oliver1. 1. Cerebra Centre for Neurodevelopmental disorders, School of Psychology, University of Birmingham, Birmingham, UK. 2. Autism Centre of Excellence, School of Education and Professional Studies, Griffith University, Mount Gravatt, Queensland, Australia. 3. Griffith Institute for Educational Research, Griffith University, Brisbane, Queensland, Australia.
Abstract
BACKGROUND: There is growing evidence to suggest that children with neurodevelopmental disorders may evidence differences in their sensory processing. The aim of this study was to compare sensory processing patterns in three genetic syndromes associated with sensory difference. METHODS: Sensory processing in Angelman syndrome (n = 91), Cornelia de Lange syndrome (n = 28) and Fragile X syndrome (n = 40) was examined using the informant report measure the Sensory Experiences Questionnaire (SEQ). RESULTS: All three groups were associated with a heightened prevalence of unusual sensory processing in comparison with normative data, evidenced in over 80% of all participants. Cross-syndrome comparisons highlighted syndrome-specific sensory processing profiles, with heightened hypo responsivity in Cornelia de Lange syndrome and sensory seeking in Angelman syndrome. CONCLUSIONS: The results have important implications for the understanding of sensory processing in genetic syndromes and the development of tailored behavioural interventions.
BACKGROUND: There is growing evidence to suggest that children with neurodevelopmental disorders may evidence differences in their sensory processing. The aim of this study was to compare sensory processing patterns in three genetic syndromes associated with sensory difference. METHODS: Sensory processing in Angelman syndrome (n = 91), Cornelia de Lange syndrome (n = 28) and Fragile X syndrome (n = 40) was examined using the informant report measure the Sensory Experiences Questionnaire (SEQ). RESULTS: All three groups were associated with a heightened prevalence of unusual sensory processing in comparison with normative data, evidenced in over 80% of all participants. Cross-syndrome comparisons highlighted syndrome-specific sensory processing profiles, with heightened hypo responsivity in Cornelia de Lange syndrome and sensory seeking in Angelman syndrome. CONCLUSIONS: The results have important implications for the understanding of sensory processing in genetic syndromes and the development of tailored behavioural interventions.
Authors: Kyra Lubbers; Eefje M Stijl; Bram Dierckx; Doesjka A Hagenaar; Leontine W Ten Hoopen; Jeroen S Legerstee; Pieter F A de Nijs; André B Rietman; Kirstin Greaves-Lord; Manon H J Hillegers; Gwendolyn C Dieleman; Sabine E Mous Journal: Front Psychiatry Date: 2022-05-16 Impact factor: 5.435