Literature DB >> 31792374

Human germline genome editing.

Rebecca A Lea1, Kathy K Niakan2.   

Abstract

With the advent of efficient, easy-to-use genome editing by CRISPR-Cas9, editing human embryos is now possible, providing tremendous opportunities to study gene function and cell fate in early human development. The technique can also be used to modify the human germline. Unresolved questions about pre-implantation human development could be addressed by basic research using CRISPR-Cas9. In this Perspective, we discuss advances in human genome editing and consider ethical questions and potential clinical implications of this technology.

Entities:  

Year:  2019        PMID： 31792374     DOI： 10.1038/s41556-019-0424-0

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  121 in total

Review 1.  Genome engineering with zinc-finger nucleases.

Authors:  Dana Carroll
Journal:  Genetics       Date:  2011-08       Impact factor: 4.562

Review 2.  TALENs: a widely applicable technology for targeted genome editing.

Authors:  J Keith Joung; Jeffry D Sander
Journal:  Nat Rev Mol Cell Biol       Date:  2012-11-21       Impact factor: 94.444

3.  Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.

Authors:  Giedrius Gasiunas; Rodolphe Barrangou; Philippe Horvath; Virginijus Siksnys
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-04       Impact factor: 11.205

4.  A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Authors:  Martin Jinek; Krzysztof Chylinski; Ines Fonfara; Michael Hauer; Jennifer A Doudna; Emmanuelle Charpentier
Journal:  Science       Date:  2012-06-28       Impact factor: 47.728

5.  Multiplex genome engineering using CRISPR/Cas systems.

Authors:  Le Cong; F Ann Ran; David Cox; Shuailiang Lin; Robert Barretto; Naomi Habib; Patrick D Hsu; Xuebing Wu; Wenyan Jiang; Luciano A Marraffini; Feng Zhang
Journal:  Science       Date:  2013-01-03       Impact factor: 47.728

6.  RNA-guided human genome engineering via Cas9.

Authors:  Prashant Mali; Luhan Yang; Kevin M Esvelt; John Aach; Marc Guell; James E DiCarlo; Julie E Norville; George M Church
Journal:  Science       Date:  2013-01-03       Impact factor: 47.728

Review 7.  Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.

Authors:  George Silva; Laurent Poirot; Roman Galetto; Julianne Smith; Guillermo Montoya; Philippe Duchateau; Frédéric Pâques
Journal:  Curr Gene Ther       Date:  2011-02       Impact factor: 4.391

8.  CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes.

Authors:  Puping Liang; Yanwen Xu; Xiya Zhang; Chenhui Ding; Rui Huang; Zhen Zhang; Jie Lv; Xiaowei Xie; Yuxi Chen; Yujing Li; Ying Sun; Yaofu Bai; Zhou Songyang; Wenbin Ma; Canquan Zhou; Junjiu Huang
Journal:  Protein Cell       Date:  2015-04-18       Impact factor: 14.870

9.  RNA-programmed genome editing in human cells.

Authors:  Martin Jinek; Alexandra East; Aaron Cheng; Steven Lin; Enbo Ma; Jennifer Doudna
Journal:  Elife       Date:  2013-01-29       Impact factor: 8.140

Review 10.  The CRISPR tool kit for genome editing and beyond.

Authors:  Mazhar Adli
Journal:  Nat Commun       Date:  2018-05-15       Impact factor: 14.919
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  11 in total

1.  Correction of the pathogenic mutation in TGM1 gene by adenine base editing in mutant embryos.

Authors:  Lu Dang; Xueliang Zhou; Xiufang Zhong; Wenxia Yu; Shisheng Huang; Hanyan Liu; Yuanyuan Chen; Wuwen Zhang; Lihua Yuan; Lei Li; Xingxu Huang; Guanglei Li; Jianqiao Liu; Guoqing Tong
Journal:  Mol Ther       Date:  2021-05-08       Impact factor: 11.454

2.  Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos.

Authors:  Gregorio Alanis-Lobato; Jasmin Zohren; Afshan McCarthy; Norah M E Fogarty; Nada Kubikova; Emily Hardman; Maria Greco; Dagan Wells; James M A Turner; Kathy K Niakan
Journal:  Proc Natl Acad Sci U S A       Date:  2021-04-09       Impact factor: 11.205

Review 3.  Harnessing the potential of CRISPR-based platforms to advance the field of hospital medicine.

Authors:  Matthew W McCarthy
Journal:  Expert Rev Anti Infect Ther       Date:  2020-05-04       Impact factor: 5.091

Review 4.  Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What's Next.

Authors:  Steven Erwood; Bin Gu
Journal:  Genes (Basel)       Date:  2020-01-29       Impact factor: 4.096

Review 5.  Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality.

Authors:  Mitsutoshi Yamada; Suguru Sato; Reina Ooka; Kazuhiro Akashi; Akihiro Nakamura; Kenji Miyado; Hidenori Akutsu; Mamoru Tanaka
Journal:  Reprod Med Biol       Date:  2020-11-03

6.  Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing.

Authors:  Styliani Markoulaki; Logan J Blaine; Stamatis Papathanasiou; Mitchell L Leibowitz; Cheng-Zhong Zhang; Rudolf Jaenisch; David Pellman
Journal:  Nat Commun       Date:  2021-10-06       Impact factor: 17.694

7.  Responsible governance of human germline genome editing in China†.

Authors:  Yaojin Peng; Jianwei Lv; Lulu Ding; Xia Gong; Qi Zhou
Journal:  Biol Reprod       Date:  2022-07-25       Impact factor: 4.161

8.  Germline Genome Editing Research: What Are Gamete Donors (Not) Informed About in Consent Forms?

Authors:  Emilia Niemiec; Heidi Carmen Howard
Journal:  CRISPR J       Date:  2020-02

9.  Gene editing and CRISPR in the clinic: current and future perspectives.

Authors:  Matthew P Hirakawa; Raga Krishnakumar; Jerilyn A Timlin; James P Carney; Kimberly S Butler
Journal:  Biosci Rep       Date:  2020-04-30       Impact factor: 3.840

10.  Detection of a biolistic delivery of fluorescent markers and CRISPR/Cas9 to the pollen tube.

Authors:  Shiori Nagahara; Tetsuya Higashiyama; Yoko Mizuta
Journal:  Plant Reprod       Date:  2021-06-19       Impact factor: 3.767
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