Literature DB >> 31786731

Discarding IVF embryos: reporting on global practices.

M Simopoulou1,2, K Sfakianoudis3, P Giannelou4,3, A Rapani4,5, E Maziotis4,5,6, P Tsioulou4,5, S Grigoriadis4,5, E Simopoulos6, D Mantas7, M Lambropoulou6, M Koutsilieris4, K Pantos3, J C Harper8.   

Abstract

PURPOSE: To provide a global scale report on a representative sample of the clinical embryology community depicting the practice of discarding supernumerary IVF embryos.
METHODS: A web-based questionnaire titled "Anonymous questionnaire on embryo disposal practices" was designed in order to ensure anonymous participation of practicing clinical embryologists around the world.
RESULTS: During a data collection period of 8 months, 703 filled-in questionnaires from 65 countries were acquired. According to the data acquired, the majority of practitioners, dispose of embryos by placing them directly in a trash can strictly dedicated for embryo disposal for both fresh and frozen cycles (39% and 36.7% respectively). Moreover, 66.4% of practitioners discard the embryos separately-case by case-at different time points during the day. Over half of embryologists (54%) wait until day 6 to discard the surplus embryos, while 65.5% do not implement a specially allocated incubator space as a designated waiting area prior to disposal. The majority of 63.1% reported that this is a witnessed procedure. The vast majority of embryologists (93%) do not employ different protocols for different groups of patients. Nonetheless, 17.8% reported the request to perform a ceremony for these embryos. Assessing the embryologists' perspective, 59.5% of participants stated that the embryology practice would benefit from a universally accepted and practiced protocol. CONCLUSION(S): This study uniquely provides insight into global embryo disposal practices and trends. Results highlight the divergence between reported practices, while indicating the significance on standardization of practice, with embryologists acknowledging the need for a universally accepted protocol implementation.

Entities:  

Keywords:  Embryo disposal practices; IVF; Surplus embryos

Mesh:

Year:  2019        PMID: 31786731      PMCID: PMC6911130          DOI: 10.1007/s10815-019-01592-w

Source DB:  PubMed          Journal:  J Assist Reprod Genet        ISSN: 1058-0468            Impact factor:   3.412


  42 in total

1.  The disposition of unused frozen embryos.

Authors:  S C Klock; S Sheinin; R R Kazer
Journal:  N Engl J Med       Date:  2001-07-05       Impact factor: 91.245

Review 2.  Are computational applications the "crystal ball" in the IVF laboratory? The evolution from mathematics to artificial intelligence.

Authors:  Mara Simopoulou; Konstantinos Sfakianoudis; Evangelos Maziotis; Nikolaos Antoniou; Anna Rapani; George Anifandis; Panagiotis Bakas; Stamatis Bolaris; Agni Pantou; Konstantinos Pantos; Michael Koutsilieris
Journal:  J Assist Reprod Genet       Date:  2018-07-27       Impact factor: 3.412

3.  Parents' conceptualization of their frozen embryos complicates the disposition decision.

Authors:  Robert D Nachtigall; Gay Becker; Carrie Friese; Anneliese Butler; Kirstin MacDougall
Journal:  Fertil Steril       Date:  2005-08       Impact factor: 7.329

4.  Immunisation recall.

Authors:  R Hursthouse
Journal:  N Z Med J       Date:  1987-09-09

5.  (Re)constructing embryos in stem cell research: exploring the meaning of embryos for people involved in fertility treatments.

Authors:  Sarah Parry
Journal:  Soc Sci Med       Date:  2005-11-14       Impact factor: 4.634

6.  The fate of cryopreserved human embryos approaching their legal limit of storage within a West Australian in-vitro fertilization clinic.

Authors:  N Darlington; P Matson
Journal:  Hum Reprod       Date:  1999-09       Impact factor: 6.918

7.  Patients' attitudes towards donation of surplus cryopreserved embryos for treatment or research.

Authors:  S Bangsbøll; A Pinborg; C Yding Andersen; A Nyboe Andersen
Journal:  Hum Reprod       Date:  2004-08-13       Impact factor: 6.918

8.  How to facilitate decisions about surplus embryos: patients' views.

Authors:  Giuliana Fuscaldo; Sarah Russell; Lynn Gillam
Journal:  Hum Reprod       Date:  2007-12       Impact factor: 6.918

Review 9.  Making IVF more effective through the evolution of prediction models: is prognosis the missing piece of the puzzle?

Authors:  Mara Simopoulou; Konstantinos Sfakianoudis; Nikolaos Antoniou; Evangelos Maziotis; Anna Rapani; Panagiotis Bakas; George Anifandis; Theodoros Kalampokas; Stamatis Bolaris; Agni Pantou; Konstantinos Pantos; Michael Koutsilieris
Journal:  Syst Biol Reprod Med       Date:  2018-08-08       Impact factor: 3.061

10.  Reflecting the 'human nature' of IVF embryos: disappearing women in ethics, law, and fertility practice.

Authors:  Jenni Millbank
Journal:  J Law Biosci       Date:  2016-11-23
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  2 in total

Review 1.  The effect of extended cryo-storage following vitrification on embryo competence: a systematic review and meta-analysis.

Authors:  S Canosa; D Cimadomo; A Conforti; R Maggiulli; A Giancani; A Tallarita; F Golia; G Fabozzi; A Vaiarelli; G Gennarelli; A Revelli; F Bongioanni; C Alviggi; F M Ubaldi; L Rienzi
Journal:  J Assist Reprod Genet       Date:  2022-02-04       Impact factor: 3.357

2.  Evaluation of the effect of the elective blastocyst-stage embryo transfer and freezing strategy on the abandonment of frozen embryos under the Taiwan National Assisted Reproduction Act.

Authors:  Kuo-Chung Lan; Ya-Jung Tseng; Yi-Ru Su; Tzu-Yu Lin; Yi-Chi Lin
Journal:  J Assist Reprod Genet       Date:  2020-01-28       Impact factor: 3.412

  2 in total

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