Na He1,2, Yingying Ding3, Jing Li3, Shiying Yuan3, Lulu Xu3, Shijie Qiao3, Xiaohui Xu3, Bowen Zhu3, Ruizi Shi3, John P Barile4, Frank Y Wong5,6,7. 1. Department of Epidemiology, School of Public Health, The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China. nhe@fudan.edu.cn. 2. Key Laboratory of Health Technology Assessment of Ministry of Health, Fudan University, Shanghai, China. nhe@fudan.edu.cn. 3. Department of Epidemiology, School of Public Health, The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China. 4. Department of Psychology, University of Hawai'i at Mānoa, Honolulu, HI, USA. 5. Department of Epidemiology, School of Public Health, The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China. fwong@fsu.edu. 6. Department of Psychology, University of Hawai'i at Mānoa, Honolulu, HI, USA. fwong@fsu.edu. 7. Center for Indigenous Nursing Research for Health Equity, Florida State University, Tallahassee, FL, USA. fwong@fsu.edu.
Abstract
PURPOSE OF REVIEW: The last 15 years have witnessed a dramatic change in HIV-related epidemiology amidst improvements in treatment and care in China. With proper treatment, HIV is now considered a chronic disease. As a consequence, many people living with HIV (PLWH) now present age-related comorbidities. We reviewed 13 topical issues concerning the epidemiology of aging with HIV in mainland China. RESULTS: Many of aging-related issues associated with the biological and physical aspects of living with HIV addressed in mainland China are consistent with the global literature. Greater prevalence of age-related comorbidities among PLWH was observed. Beyond biological mechanisms associated with HIV infection and traditional risk factors, other factors play a vital role in the aging process among PLWH. A stronger focus on screening, prevention, and management of non-HIV co-morbidities among PLWH is now warranted. Macro-social factors need to be integrated into next generation of clinical and/or behavioral HIV research to inform disease progression and management as well as prevention.
PURPOSE OF REVIEW: The last 15 years have witnessed a dramatic change in HIV-related epidemiology amidst improvements in treatment and care in China. With proper treatment, HIV is now considered a chronic disease. As a consequence, many people living with HIV (PLWH) now present age-related comorbidities. We reviewed 13 topical issues concerning the epidemiology of aging with HIV in mainland China. RESULTS: Many of aging-related issues associated with the biological and physical aspects of living with HIV addressed in mainland China are consistent with the global literature. Greater prevalence of age-related comorbidities among PLWH was observed. Beyond biological mechanisms associated with HIV infection and traditional risk factors, other factors play a vital role in the aging process among PLWH. A stronger focus on screening, prevention, and management of non-HIV co-morbidities among PLWH is now warranted. Macro-social factors need to be integrated into next generation of clinical and/or behavioral HIV research to inform disease progression and management as well as prevention.
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