Xiaoning Liu1, Jing Cao1, Zheng Zhu2,3, Xia Zhao4, Jing Zhou1, Qiuxia Deng1, Liyuan Zhang1, Hui Wang5. 1. The Third People's Hospital of Shenzhen, Shenzhen, China. 2. Fudan University School of Nursing, Shanghai, China. zhengzhu@fudan.edu.cn. 3. Fudan University Centre for Evidence-based Nursing: A Joanna Briggs Institute Centre of Excellence, Shanghai, China. zhengzhu@fudan.edu.cn. 4. Peking Union Medical College Hospital, Beijing, China. 5. The Third People's Hospital of Shenzhen, Shenzhen, China. huiwang98@szsy.sustech.edu.cn.
Abstract
BACKGROUND: Nutrition is a crucial factor that can impact morbidity and mortality in older people living with HIV (PLWH). Studies on nutritional risk and nutritional status in all age groups in PLWH have been conducted. However, few studies have focused on nutritional risk in older PLWH. This study aimed to describe the nutritional risk and nutritional status in older PLWH, and explore factors associated with nutritional risk and undernutrition status. METHODS: We conducted a cross-sectional study. We recruited participants aged 50 years or older from the Third People's Hospital of Shenzhen from January 2016 to May 2019. Nutritional risk and nutritional status were evaluated by the Nutritional Risk Screening 2002 (NRS 2002) tool, body mass index (BMI), albumin level, and prealbumin level on the first day of admission. Logistic regression models were used to identify the factors associated with undernutrition based on the BMI, albumin, and prealbumin criteria. RESULTS: A total of 196 older PLWH were included in the analysis. We found that 36% of hospitalized older PLWH had nutritional risk, and 12-56% of them had undernutrition based on the BMI, albumin, and prealbumin criteria. An increased nutritional risk score was associated with older age (β = 0.265 CI [0.021, 0.096], P = 0.002), a higher viral load (β = - 0.186 CI [- 0.620, - 0.037], P = 0.028), a lower BMI (β = - 0.287 CI [- 0.217, - 0.058], P = 0.001), and a lower albumin level (β = - 0.324 CI [- 8.896, - 1.230], P = 0.010). The CD4 count was associated with the prevalence of undernutrition based on the albumin criterion (OR = 15.637 CI [2.742, 89.178], P = 0.002). CONCLUSION: Our study indicated that nutritional screening, assessment, and management should be routinely performed in hospitalized older PLWH. HIV-specific measures should be used to assess nutritional risk, and albumin, BMI, and other assessments should be used in combination to identify undernutrition in older PLWH.
BACKGROUND: Nutrition is a crucial factor that can impact morbidity and mortality in older people living with HIV (PLWH). Studies on nutritional risk and nutritional status in all age groups in PLWH have been conducted. However, few studies have focused on nutritional risk in older PLWH. This study aimed to describe the nutritional risk and nutritional status in older PLWH, and explore factors associated with nutritional risk and undernutrition status. METHODS: We conducted a cross-sectional study. We recruited participants aged 50 years or older from the Third People's Hospital of Shenzhen from January 2016 to May 2019. Nutritional risk and nutritional status were evaluated by the Nutritional Risk Screening 2002 (NRS 2002) tool, body mass index (BMI), albumin level, and prealbumin level on the first day of admission. Logistic regression models were used to identify the factors associated with undernutrition based on the BMI, albumin, and prealbumin criteria. RESULTS: A total of 196 older PLWH were included in the analysis. We found that 36% of hospitalized older PLWH had nutritional risk, and 12-56% of them had undernutrition based on the BMI, albumin, and prealbumin criteria. An increased nutritional risk score was associated with older age (β = 0.265 CI [0.021, 0.096], P = 0.002), a higher viral load (β = - 0.186 CI [- 0.620, - 0.037], P = 0.028), a lower BMI (β = - 0.287 CI [- 0.217, - 0.058], P = 0.001), and a lower albumin level (β = - 0.324 CI [- 8.896, - 1.230], P = 0.010). The CD4 count was associated with the prevalence of undernutrition based on the albumin criterion (OR = 15.637 CI [2.742, 89.178], P = 0.002). CONCLUSION: Our study indicated that nutritional screening, assessment, and management should be routinely performed in hospitalized older PLWH. HIV-specific measures should be used to assess nutritional risk, and albumin, BMI, and other assessments should be used in combination to identify undernutrition in older PLWH.
Entities:
Keywords:
AIDS; Aging; HIV; Nutrition risk; Nutrition status
Authors: Julius Y Fonsah; Alfred K Njamnshi; Charles Kouanfack; Fang Qiu; Dora M Njamnshi; Claude T Tagny; Emilienne Nchindap; Léopoldine Kenmogne; Dora Mbanya; Robert Heaton; Georgette D Kanmogne Journal: PLoS One Date: 2017-01-31 Impact factor: 3.240
Authors: T Cederholm; G L Jensen; M I T D Correia; M C Gonzalez; R Fukushima; T Higashiguchi; G Baptista; R Barazzoni; R Blaauw; A J S Coats; A N Crivelli; D C Evans; L Gramlich; V Fuchs-Tarlovsky; H Keller; L Llido; A Malone; K M Mogensen; J E Morley; M Muscaritoli; I Nyulasi; M Pirlich; V Pisprasert; M A E de van der Schueren; S Siltharm; P Singer; K Tappenden; N Velasco; D Waitzberg; P Yamwong; J Yu; A Van Gossum; C Compher Journal: J Cachexia Sarcopenia Muscle Date: 2019-02 Impact factor: 12.910