Literature DB >> 31745495

Handheld Adaptive Optics Scanning Laser Ophthalmoscope.

Theodore DuBose1, Derek Nankivil1, Francesco LaRocca1, Gar Waterman1, Kristen Hagan1, James Polans1, Brenton Keller1, Du Tran-Viet2, Lejla Vajzovic2, Anthony N Kuo2,1, Cynthia A Toth2,1, Joseph A Izatt1,2, Sina Farsiu1,2.   

Abstract

Adaptive optics scanning laser ophthalmoscopy (AOSLO) has enabled in vivo visualization and enhanced understanding of retinal structure and function. Current generation AOSLOs have a large footprint and are mainly limited to imaging cooperative adult subjects. To extend the application of AOSLO to new patient populations, we have designed the first portable handheld AOSLO (HAOSLO) system. By incorporating a novel computational wavefront sensorless AO algorithm and custom optics, we have miniaturized our HAOSLO to weigh less than 200 grams. HAOSLO imaged the cones closest to the fovea with a handheld probe in adults and captured the first AO-enhanced image of cones in infants.

Entities:  

Year:  2018        PMID： 31745495      PMCID： PMC6863352          DOI： 10.1364/OPTICA.5.001027

Source DB:  PubMed          Journal:  Optica            Impact factor:   11.104


  58 in total

1.  Normal values and standard deviations for pupil diameter and interpupillary distance in subjects aged 1 month to 19 years.

Authors:  Colleen MacLachlan; Howard C Howland
Journal:  Ophthalmic Physiol Opt       Date:  2002-05       Impact factor: 3.117

2.  Optimization of high-order harmonic generation by adaptive control of a sub-10-fs pulse wave front.

Authors:  Paolo Villoresi; Stefano Bonora; Michele Pascolini; Luca Poletto; Giuseppe Tondello; Caterina Vozzi; Mauro Nisoli; Giuseppe Sansone; Salvatore Stagira; Sandro De Silvestri
Journal:  Opt Lett       Date:  2004-01-15       Impact factor: 3.776

3.  Simulated annealing in ocular adaptive optics.

Authors:  S Zommer; E N Ribak; S G Lipson; J Adler
Journal:  Opt Lett       Date:  2006-04-01       Impact factor: 3.776

4.  True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe.

Authors:  Francesco LaRocca; Derek Nankivil; Sina Farsiu; Joseph A Izatt
Journal:  Biomed Opt Express       Date:  2014-08-27       Impact factor: 3.732

5.  Wide-field retinal optical coherence tomography with wavefront sensorless adaptive optics for enhanced imaging of targeted regions.

Authors:  James Polans; Brenton Keller; Oscar M Carrasco-Zevallos; Francesco LaRocca; Elijah Cole; Heather E Whitson; Eleonora M Lad; Sina Farsiu; Joseph A Izatt
Journal:  Biomed Opt Express       Date:  2016-12-02       Impact factor: 3.732

6.  Disruption of the retinal parafoveal capillary network in type 2 diabetes before the onset of diabetic retinopathy.

Authors:  Johnny Tam; Kavita P Dhamdhere; Pavan Tiruveedhula; Silvestre Manzanera; Shirin Barez; Marcus A Bearse; Anthony J Adams; Austin Roorda
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-11-29       Impact factor: 4.799

7.  In vivo imaging of photoreceptor disruption associated with age-related macular degeneration: A pilot study.

Authors:  Adam Boretsky; Faraz Khan; Garrett Burnett; Daniel X Hammer; R Daniel Ferguson; Frederik van Kuijk; Massoud Motamedi
Journal:  Lasers Surg Med       Date:  2012-08-28       Impact factor: 4.025

8.  Cone and rod loss in Stargardt disease revealed by adaptive optics scanning light ophthalmoscopy.

Authors:  Hongxin Song; Ethan A Rossi; Lisa Latchney; Angela Bessette; Edwin Stone; Jennifer J Hunter; David R Williams; Mina Chung
Journal:  JAMA Ophthalmol       Date:  2015-10       Impact factor: 7.389

9.  In vivo cellular-resolution retinal imaging in infants and children using an ultracompact handheld probe.

Authors:  Francesco LaRocca; Derek Nankivil; Theodore DuBose; Cynthia A Toth; Sina Farsiu; Joseph A Izatt
Journal:  Nat Photonics       Date:  2016-08-01       Impact factor: 38.771

10.  Canine retina has a primate fovea-like bouquet of cone photoreceptors which is affected by inherited macular degenerations.

Authors:  William A Beltran; Artur V Cideciyan; Karina E Guziewicz; Simone Iwabe; Malgorzata Swider; Erin M Scott; Svetlana V Savina; Gordon Ruthel; Frank Stefano; Lingli Zhang; Richard Zorger; Alexander Sumaroka; Samuel G Jacobson; Gustavo D Aguirre
Journal:  PLoS One       Date:  2014-03-05       Impact factor: 3.240
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  8 in total

1.  Automated fast computational adaptive optics for optical coherence tomography based on a stochastic parallel gradient descent algorithm.

Authors:  Dan Zhu; Ruoyan Wang; Mantas Žurauskas; Paritosh Pande; Jinci Bi; Qun Yuan; Lingjie Wang; Zhishan Gao; Stephen A Boppart
Journal:  Opt Express       Date:  2020-08-03       Impact factor: 3.894

2.  COVID-19 in Ophthalmology. Current Disease Status and Challenges during Clinical Practice.

Authors:  Georgios Bontzos; Anastasia Gkiala; Christina Karakosta; Neofytos Maliotis; Efstathios T Detorakis
Journal:  Maedica (Bucur)       Date:  2021-12

3.  Non-interferometric volumetric imaging in living human retina by confocal oblique scanning laser ophthalmoscopy.

Authors:  Wenjun Shao; Ji Yi
Journal:  Biomed Opt Express       Date:  2022-05-24       Impact factor: 3.562

4.  Multimodal handheld adaptive optics scanning laser ophthalmoscope.

Authors:  Kristen Hagan; Theodore DuBose; David Cunefare; Gar Waterman; Jongwan Park; Corey Simmerer; Anthony N Kuo; Ryan P McNabb; Joseph A Izatt; Sina Farsiu
Journal:  Opt Lett       Date:  2020-09-01       Impact factor: 3.776

5.  RAC-CNN: multimodal deep learning based automatic detection and classification of rod and cone photoreceptors in adaptive optics scanning light ophthalmoscope images.

Authors:  David Cunefare; Alison L Huckenpahler; Emily J Patterson; Alfredo Dubra; Joseph Carroll; Sina Farsiu
Journal:  Biomed Opt Express       Date:  2019-07-08       Impact factor: 3.562

Review 6.  Advances in multimodal imaging in ophthalmology.

Authors:  Morgan J Ringel; Eric M Tang; Yuankai K Tao
Journal:  Ther Adv Ophthalmol       Date:  2021-03-19

7.  High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source.

Authors:  Shuibin Ni; Xiang Wei; Ringo Ng; Susan Ostmo; Michael F Chiang; David Huang; Yali Jia; J Peter Campbell; Yifan Jian
Journal:  Biomed Opt Express       Date:  2021-05-20       Impact factor: 3.732

8.  Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography.

Authors:  Joseph D Malone; Mohamed T El-Haddad; Suhaas S Yerramreddy; Ipek Oguz; Yuankai K Tao
Journal:  Neurophotonics       Date:  2019-07-03       Impact factor: 3.593
  8 in total

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