Literature DB >> 3164476

Identification of another member of the transforming growth factor type beta gene family.

P ten Dijke1, P Hansen, K K Iwata, C Pieler, J G Foulkes.   

Abstract

We report here the complete amino acid sequence of another member of the type beta transforming growth factor gene family, deduced from the nucleotide sequence of three overlapping cDNA clones. The C-terminal 112 amino acids share approximately 80% sequence identity with type beta 1 and beta 2 transforming growth factors, with many of the remaining differences being conservative substitutions. By analogy to type beta 1 and type beta 2 transforming growth factors, we predict the protein to be synthesized as a 412 amino acid precursor that undergoes proteolytic cleavage to produce the mature polypeptide.

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Year:  1988        PMID: 3164476      PMCID: PMC280506          DOI: 10.1073/pnas.85.13.4715

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  32 in total

1.  A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta.

Authors:  P Rossi; G Karsenty; A B Roberts; N S Roche; M B Sporn; B de Crombrugghe
Journal:  Cell       Date:  1988-02-12       Impact factor: 41.582

2.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

3.  A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides.

Authors:  D Perlman; H O Halvorson
Journal:  J Mol Biol       Date:  1983-06-25       Impact factor: 5.469

4.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

5.  Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance.

Authors:  R A Flavell; J M Kooter; E De Boer; P F Little; R Williamson
Journal:  Cell       Date:  1978-09       Impact factor: 41.582

6.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

7.  Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

Authors:  R K Assoian; A Komoriya; C A Meyers; D M Miller; M B Sporn
Journal:  J Biol Chem       Date:  1983-06-10       Impact factor: 5.157

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Isolation of beta-globin-related genes from a human cosmid library.

Authors:  F G Grosveld; H H Dahl; E de Boer; R A Flavell
Journal:  Gene       Date:  1981-04       Impact factor: 3.688

10.  Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA.

Authors:  C Auffray; F Rougeon
Journal:  Eur J Biochem       Date:  1980-06
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  54 in total

1.  Transforming growth factor-ßs as modulators of pericellular proteolytic events.

Authors:  J Keski-Oja; J Lohi; M Laiho
Journal:  Cytotechnology       Date:  1989-12       Impact factor: 2.058

2.  The use of autologous blood-derived growth factors in bone regeneration.

Authors:  Roberto Civinini; Armando Macera; Lorenzo Nistri; Birgit Redl; Massimo Innocenti
Journal:  Clin Cases Miner Bone Metab       Date:  2011-01

Review 3.  TGF-beta: problems and prospects.

Authors:  M B Sporn; A B Roberts
Journal:  Cell Regul       Date:  1990-11

4.  Epigenetic Interactions and Gene Expression in Peri-Implantation Mouse Embryo Development.

Authors:  Jean J Latimer; Roger A Pedersen
Journal:  Mod Cell Biol       Date:  1993

5.  Sequence specific protein binding to and activation of the TGF-beta 3 promoter through a repeated TCCC motif.

Authors:  R Lafyatis; F Denhez; T Williams; M Sporn; A Roberts
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

6.  Autocrine factor-independent growth of mammalian fibroblasts established in fully synthetic medium: no v-onc requirement in establishment.

Authors:  M Hill; J Hillova; R Mariage-Samson
Journal:  In Vitro Cell Dev Biol       Date:  1990-01

7.  Purification and partial amino acid sequence of suppressive lymphokine from a CD8+ CD57+ human T hybridoma.

Authors:  C P Quan; S Watanabe; F Vuillier; R Pires; T Matsuo; M Stanislawski; J Pillot; J P Bouvet
Journal:  Immunology       Date:  1993-02       Impact factor: 7.397

8.  A GC-rich domain with bifunctional effects on mRNA and protein levels: implications for control of transforming growth factor beta 1 expression.

Authors:  L Scotto; R K Assoian
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

9.  Activin-A binding and biochemical effects in osteoblast-enriched cultures from fetal-rat parietal bone.

Authors:  M Centrella; T L McCarthy; E Canalis
Journal:  Mol Cell Biol       Date:  1991-01       Impact factor: 4.272

10.  Dominant negative mutants of transforming growth factor-beta 1 inhibit the secretion of different transforming growth factor-beta isoforms.

Authors:  A R Lopez; J Cook; P L Deininger; R Derynck
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

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