Literature DB >> 3163908

In vitro activity of cefotetan compared with that of other antimicrobial agents against anaerobic bacteria.

H M Wexler1, S M Finegold.   

Abstract

The activity of cefotetan against 430 strains of anaerobic bacteria was compared with that of cefoxitin, ceftizoxime, clindamycin, metronidazole, and chloramphenicol. Percent susceptible values for the Bacteroides fragilis group were 60, 80, 29, 86, 100, and 100%, respectively. Percent susceptible values for the B. fragilis species were 91, 92, 46, 98, 100, and 100%, respectively. Non-B. fragilis-group Bacteroides species were inhibited very well (90 to 100%) by all drugs except ceftizoxime (80%). Cefotetan and metronidazole were the most active agents against Clostridium difficile. Percent susceptible values for all strains were 72, 79, 44, 82, 93, and 98%, respectively.

Entities:  

Mesh:

Substances:

Year:  1988        PMID: 3163908      PMCID: PMC172231          DOI: 10.1128/AAC.32.4.601

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  12 in total

Review 1.  Antimicrobial resistance in Bacteroides.

Authors:  H M Wexler; S M Finegold
Journal:  J Antimicrob Chemother       Date:  1987-02       Impact factor: 5.790

2.  Pharmacokinetics of ceftizoxime.

Authors:  R E Cutler; A D Blair; E D Burgess; D Parks
Journal:  J Antimicrob Chemother       Date:  1982-11       Impact factor: 5.790

3.  Activity in vitro of cefotetan against non-sporing anaerobes: a comparative study.

Authors:  G Ruckdeschel
Journal:  J Antimicrob Chemother       Date:  1983-01       Impact factor: 5.790

4.  Inhibitory activity of cefotetan and other beta-lactams against anaerobes.

Authors:  H Werner
Journal:  J Antimicrob Chemother       Date:  1983-01       Impact factor: 5.790

5.  Pharmacokinetics of single intravenous and intramuscular doses of cefotetan in normal human volunteers.

Authors:  J Guibert; M D Kitzis; C Yvelin; J F Acar
Journal:  J Antimicrob Chemother       Date:  1983-01       Impact factor: 5.790

6.  Antimicrobial susceptibilities of 1,292 isolates of the Bacteroides fragilis group in the United States: comparison of 1981 with 1982.

Authors:  G J Cuchural; F P Tally; N V Jacobus; S L Gorbach; K Aldridge; T Cleary; S M Finegold; G Hill; P Iannini; J P O'Keefe
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

7.  Cefotetan: in-vitro antibacterial activity and susceptibility to beta-lactamases.

Authors:  I Phillips; A King; K Shannon; C Warren
Journal:  J Antimicrob Chemother       Date:  1983-01       Impact factor: 5.790

8.  In vitro activity of cefbuperazone against anaerobic bacteria.

Authors:  H Wexler; W T Carter; B H Harris; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

9.  Comparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species.

Authors:  K E Aldridge; C V Sanders; A Janney; S Faro; R L Marier
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

10.  In vitro efficacy of sulbactam combined with ampicillin against anaerobic bacteria.

Authors:  H M Wexler; B Harris; W T Carter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

View more
  7 in total

Review 1.  New developments and concepts in antimicrobial therapy for intra-abdominal infections.

Authors:  Z Younes; D A Johnson
Journal:  Curr Gastroenterol Rep       Date:  2000-08

2.  Susceptibilities of members of the Bacteroides fragilis group to 11 antimicrobial agents.

Authors:  R Horn; J Lavallée; H G Robson
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

Review 3.  Susceptibility testing of anaerobic bacteria: myth, magic, or method?

Authors:  H M Wexler
Journal:  Clin Microbiol Rev       Date:  1991-10       Impact factor: 26.132

4.  Survey of Bacteroides fragilis group susceptibility patterns in Canada.

Authors:  A M Bourgault; F Lamothe; D J Hoban; M T Dalton; P C Kibsey; G Harding; J A Smith; D E Low; H Gilbert
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191

Review 5.  Metronidazole. A therapeutic review and update.

Authors:  C D Freeman; N E Klutman; K C Lamp
Journal:  Drugs       Date:  1997-11       Impact factor: 9.546

6.  Cefotetan: a second-generation cephalosporin active against anaerobic bacteria. Committee on Antimicrobial Agents, Canadian Infectious Disease Society.

Authors:  M J Gribble
Journal:  CMAJ       Date:  1994-09-01       Impact factor: 8.262

7.  In vitro activity of FK037, a new parenteral cephalosporin, against anaerobic bacteria.

Authors:  N Kato; H Kato; Y Tanaka; K Bando; K Watanabe; K Ueno
Journal:  Antimicrob Agents Chemother       Date:  1993-05       Impact factor: 5.191

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.