Literature DB >> 31585213

Challenges and pitfalls in the development of liposomal delivery systems for cancer therapy.

Seyedeh Alia Moosavian1, Vanessa Bianconi2, Matteo Pirro2, Amirhossein Sahebkar3.   

Abstract

Despite considerable advances in the application of liposomal drug delivery systems in cancer treatment, the clinical application of liposomal formulations has been limited by many factors. It seems that there is a wide gap between results of experimental studies and clinical application of liposomes. In this review, we discuss barriers which limit the translation of liposomal delivery systems in cancer therapy. The main focus of this review will be on differences between preclinical and clinical studies and potential approaches to overcome the main pitfalls in the clinical application of liposomal delivery systems.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cancer; Chemotherapy; Drug delivery; Liposome; Nanomedicine

Mesh：

Substances：

Year:  2019        PMID： 31585213     DOI： 10.1016/j.semcancer.2019.09.025

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN： 1044-579X            Impact factor:   15.707


  10 in total

Review 1.  Recent advances in liposome formulations for breast cancer therapeutics.

Authors:  Biyao Yang; Bo-Ping Song; Shaina Shankar; Anna Guller; Wei Deng
Journal:  Cell Mol Life Sci       Date:  2021-05-11       Impact factor: 9.261

Review 2.  Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy.

Authors:  Yilei Lu; Siqi Wang; Yuhang Wang; Mingshan Li; Yili Liu; Dongwei Xue
Journal:  Front Oncol       Date:  2022-05-24       Impact factor: 5.738

3.  Targeting lung cancer stem cells using combination of Tel and Docetaxel liposomes in 3D cultures and tumor xenografts.

Authors:  Peggy Arthur; Nilkumar Patel; Sunil Kumar Surapaneni; Arindam Mondal; Aragaw Gebeyehu; Arvind Bagde; Shallu Kutlehria; Ebony Nottingham; Mandip Singh
Journal:  Toxicol Appl Pharmacol       Date:  2020-06-12       Impact factor: 4.219

4.  Therapeutic Effect of Doxorubicin-Chlorin E6-Loaded Mesoporous Silica Nanoparticles Combined with Ultrasound on Triple-Negative Breast Cancer.

Authors:  Peng Xu; Jia Yao; Zhen Li; Meng Wang; Linghui Zhou; Guansheng Zhong; Yi Zheng; Na Li; Zhen Zhai; Si Yang; Ying Wu; Dai Zhang; Zhijun Dai
Journal:  Int J Nanomedicine       Date:  2020-04-21

Review 5.  Nanocarrier-Based Drug Delivery for Melanoma Therapeutics.

Authors:  Mingming Song; Chang Liu; Siyu Chen; Wenxiang Zhang
Journal:  Int J Mol Sci       Date:  2021-02-13       Impact factor: 5.923

6.  Rhodamine 101 Conjugates of Triterpenoic Amides Are of Comparable Cytotoxicity as Their Rhodamine B Analogs.

Authors:  Niels V Heise; Daniel Major; Sophie Hoenke; Marie Kozubek; Immo Serbian; René Csuk
Journal:  Molecules       Date:  2022-03-29       Impact factor: 4.411

Review 7.  Nanomedicine and versatile therapies for cancer treatment.

Authors:  Aparna Shukla; Pralay Maiti
Journal:  MedComm (2020)       Date:  2022-08-18

8.  Targeting therapy and tumor microenvironment remodeling of triple-negative breast cancer by ginsenoside Rg3 based liposomes.

Authors:  Jiaxuan Xia; Shuya Zhang; Ru Zhang; Anni Wang; Ying Zhu; Meichen Dong; Shaojie Ma; Chao Hong; Shengyao Liu; Dan Wang; Jianxin Wang
Journal:  J Nanobiotechnology       Date:  2022-09-15       Impact factor: 9.429

9.  The liposomal delivery of hydrophobic oxidovanadium complexes imparts highly effective cytotoxicity and differentiating capacity in neuroblastoma tumour cells.

Authors:  Elsa Irving; Aristides D Tagalakis; Ruhina Maeshima; Stephen L Hart; Simon Eaton; Ari Lehtonen; Andrew W Stoker
Journal:  Sci Rep       Date:  2020-10-07       Impact factor: 4.379

Review 10.  Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges.

Authors:  Miguel Olivas-Aguirre; Liliana Torres-López; Kathya Villatoro-Gómez; Sonia Mayra Perez-Tapia; Igor Pottosin; Oxana Dobrovinskaya
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-17
  10 in total

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