| Literature DB >> 33974093 |
Biyao Yang1, Bo-Ping Song1,2, Shaina Shankar1,3, Anna Guller1,4, Wei Deng5.
Abstract
Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we discuss liposome design with the targeting feature and triggering functions. We also summarise the recent progress (since 2014) in liposome-based therapeutics for breast cancer including chemotherapy and gene therapy. We finally identify some challenges on the liposome technology development for the future clinical translation.Entities:
Keywords: Breast cancer; Cancer therapy; Liposomal delivery; Triggerable liposomes
Year: 2021 PMID: 33974093 DOI: 10.1007/s00018-021-03850-6
Source DB: PubMed Journal: Cell Mol Life Sci ISSN: 1420-682X Impact factor: 9.261