Literature DB >> 31580218

Establishing the V̇o2 versus constant-work-rate relationship from ramp-incremental exercise: simple strategies for an unsolved problem.

Danilo Iannetta1, Rafael de Almeida Azevedo1, Daniel A Keir2, Juan M Murias1.   

Abstract

The dissociation between constant work rate of O2 uptake (V̇o2) and ramp V̇o2 at a given work rate might be mitigated during slowly increasing ramp protocols. This study characterized the V̇o2 dynamics in response to five different ramp protocols and constant-work-rate trials at the maximal metabolic steady state (MMSS) to characterize 1) the V̇o2 gain (G) in the moderate, heavy, and severe domains, 2) the mean response time of V̇o2 (MRT), and 3) the work rates at lactate threshold (LT) and respiratory compensation point (RCP). Eleven young individuals performed five ramp tests (5, 10, 15, 25, and 30 W/min), four to five time-to-exhaustions for critical power estimation, and two to three constant-work-rate trials for confirmation of the work rate at MMSS. G was greatest during the slowest ramp and progressively decreased with increasing ramp slopes (from ~12 to ~8 ml·min-1·W-1, P < 0.05). The MRT was smallest during the slowest ramp slopes and progressively increased with faster ramp slopes (1 ± 1, 2 ± 1, 5 ± 3, and 10 ± 4, 15 ± 6 W, P < 0.05). After "left shifting" the ramp V̇o2 by the MRT, the work rate at LT was constant regardless of the ramp slope (~150 W, P > 0.05). The work rate at MMSS was 215 ± 55 W and was similar and highly correlated with the work rate at RCP during the 5 W/min ramp (P > 0.05, r = 0.99; Lin's concordance coefficient = 0.99; bias = -3 W; root mean square error = 6 W). Findings showed that the dynamics of V̇o2 (i.e., G) during ramp exercise explain the apparent dichotomy existing with constant-work-rate exercise. When these dynamics are appropriately "resolved", LT is constant regardless of the ramp slope of choice, and RCP and MMSS display minimal variations between each other.NEW & NOTEWORTHY This study demonstrates that the dynamics of V̇o2 during ramp-incremental exercise are dependent on the characteristics of the increments in work rate, such that during slow-incrementing ramp protocols the magnitude of the dissociation between ramp V̇o2 and constant V̇o2 at a given work rate is reduced. Accurately accounting for these dynamics ensures correct characterizations of the V̇o2 kinetics at ramp onset and allows appropriate comparisons between ramp and constant-work-rate exercise-derived indexes of exercise intensity.

Entities:  

Keywords:  V̇o2 kinetics; exercise intensity domains; lactate threshold; mean response time; respiratory compensation point

Year:  2019        PMID: 31580218      PMCID: PMC6962604          DOI: 10.1152/japplphysiol.00508.2019

Source DB:  PubMed          Journal:  J Appl Physiol (1985)        ISSN: 0161-7567


  41 in total

1.  On issues of confidence in determining the time constant for oxygen uptake kinetics.

Authors:  G H Markovitz; J W Sayre; T W Storer; C B Cooper
Journal:  Br J Sports Med       Date:  2004-10       Impact factor: 13.800

2.  Constructing quasi-linear V̇O2 responses from nonlinear parameters.

Authors:  Samuel L Wilcox; Ryan M Broxterman; Thomas J Barstow
Journal:  J Appl Physiol (1985)       Date:  2015-11-12

3.  Influence of muscle metabolic heterogeneity in determining the V̇o2p kinetic response to ramp-incremental exercise.

Authors:  Daniel A Keir; Alan P Benson; Lorenzo K Love; Taylor C Robertson; Harry B Rossiter; John M Kowalchuk
Journal:  J Appl Physiol (1985)       Date:  2015-12-17

4.  The Respiratory Compensation Point is Not a Valid Surrogate for Critical Power.

Authors:  Jeffrey A Leo; Surendran Sabapathy; Michael J Simmonds; Troy J Cross
Journal:  Med Sci Sports Exerc       Date:  2017-07       Impact factor: 5.411

5.  The Respiratory Compensation Point and the Deoxygenation Break Point Are Valid Surrogates for Critical Power and Maximum Lactate Steady State.

Authors:  Daniel A Keir; Silvia Pogliaghi; Juan M Murias
Journal:  Med Sci Sports Exerc       Date:  2018-11       Impact factor: 5.411

6.  Breath-by-breath pulmonary O2 uptake kinetics: effect of data processing on confidence in estimating model parameters.

Authors:  Daniel A Keir; Juan M Murias; Donald H Paterson; John M Kowalchuk
Journal:  Exp Physiol       Date:  2014-07-25       Impact factor: 2.969

7.  Exercise Thresholds on Trial: Are They Really Equivalent?

Authors:  Kevin Caen; Kobe Vermeire; Jan G Bourgois; Jan Boone
Journal:  Med Sci Sports Exerc       Date:  2018-06       Impact factor: 5.411

8.  Effect of interbreath fluctuations on characterizing exercise gas exchange kinetics.

Authors:  N Lamarra; B J Whipp; S A Ward; K Wasserman
Journal:  J Appl Physiol (1985)       Date:  1987-05

9.  Pulmonary O₂ uptake and muscle deoxygenation kinetics are slowed in the upper compared with lower region of the moderate-intensity exercise domain in older men.

Authors:  Matthew D Spencer; Juan M Murias; John M Kowalchuk; Donald H Paterson
Journal:  Eur J Appl Physiol       Date:  2011-02-06       Impact factor: 3.078

Review 10.  The oxygen uptake response to incremental ramp exercise: methodogical and physiological issues.

Authors:  Jan Boone; Jan Bourgois
Journal:  Sports Med       Date:  2012-06-01       Impact factor: 11.928

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  13 in total

1.  Interlimb differences in parameters of aerobic function and local profiles of deoxygenation during double-leg and counterweighted single-leg cycling.

Authors:  Danilo Iannetta; Louis Passfield; Ahmad Qahtani; Martin J MacInnis; Juan M Murias
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-10-16       Impact factor: 3.619

2.  NIRS-derived skeletal muscle oxidative capacity is correlated with aerobic fitness and independent of sex.

Authors:  Austin T Beever; Thomas R Tripp; Jenny Zhang; Martin J MacInnis
Journal:  J Appl Physiol (1985)       Date:  2020-07-23

Review 3.  Identification of Non-Invasive Exercise Thresholds: Methods, Strategies, and an Online App.

Authors:  Daniel A Keir; Danilo Iannetta; Felipe Mattioni Maturana; John M Kowalchuk; Juan M Murias
Journal:  Sports Med       Date:  2021-10-25       Impact factor: 11.136

4.  Relationship Between the Critical Power Test and a 20-min Functional Threshold Power Test in Cycling.

Authors:  Bettina Karsten; Luca Petrigna; Andreas Klose; Antonino Bianco; Nathan Townsend; Christoph Triska
Journal:  Front Physiol       Date:  2021-01-22       Impact factor: 4.566

5.  Photobiomodulation 30 min or 6 h Prior to Cycling Does Not Alter Resting Blood Flow Velocity, Exercise-Induced Physiological Responses or Time to Exhaustion in Healthy Men.

Authors:  Yago Medeiros Dutra; Gabriel Machado Claus; Elvis de Souza Malta; Daniela Moraes de Franco Seda; Anderson Saranz Zago; Eduardo Zapaterra Campos; Cleber Ferraresi; Alessandro Moura Zagatto
Journal:  Front Physiol       Date:  2021-01-15       Impact factor: 4.566

6.  Graded exercise test with or without load carriage similarly measures maximal oxygen uptake in young males and females.

Authors:  Zhenhuan Wang; Muhammed M Atakan; Xu Yan; Hüseyin H Turnagöl; Honglei Duan; Li Peng
Journal:  PLoS One       Date:  2021-02-01       Impact factor: 3.240

7.  Individual cardiovascular responsiveness to work-matched exercise within the moderate- and severe-intensity domains.

Authors:  Felipe Mattioni Maturana; Philipp Schellhorn; Gunnar Erz; Christof Burgstahler; Manuel Widmann; Barbara Munz; Rogerio N Soares; Juan M Murias; Ansgar Thiel; Andreas M Nieß
Journal:  Eur J Appl Physiol       Date:  2021-04-03       Impact factor: 3.078

8.  Ramp vs. step tests: valid alternatives to determine the maximal lactate steady-state intensity?

Authors:  Kevin Caen; Silvia Pogliaghi; Maarten Lievens; Kobe Vermeire; Jan G Bourgois; Jan Boone
Journal:  Eur J Appl Physiol       Date:  2021-03-16       Impact factor: 3.078

9.  Relationship Between Critical Power and Different Lactate Threshold Markers in Recreational Cyclists.

Authors:  Pedro L Valenzuela; Lidia B Alejo; Almudena Montalvo-Pérez; Jaime Gil-Cabrera; Eduardo Talavera; Alejandro Lucia; David Barranco-Gil
Journal:  Front Physiol       Date:  2021-06-09       Impact factor: 4.566

10.  Cardiorespiratory fitness assessment using risk-stratified exercise testing and dose-response relationships with disease outcomes.

Authors:  Tomas I Gonzales; Kate Westgate; Tessa Strain; Stefanie Hollidge; Justin Jeon; Dirk L Christensen; Jorgen Jensen; Nicholas J Wareham; Søren Brage
Journal:  Sci Rep       Date:  2021-07-28       Impact factor: 4.379

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