Literature DB >> 31501264

Evidence-Based Genetic Counseling for Psychiatric Disorders: A Road Map.

Jehannine C Austin1,2.   

Abstract

Psychiatric disorders, such as schizophrenia, depression, anxiety, and bipolar disorder, are common conditions that arise as a result of complex and heterogeneous combinations of genetic and environmental factors. In contrast to childhood neurodevelopmental conditions such as autism and intellectual disability, there are no clinical practice guidelines for applying genetic testing in the context of these conditions. But genetic counseling and genetic testing are not synonymous, and people who live with psychiatric disorders and their family members are often interested in what psychiatric genetic counseling can offer. Further, research shows that it can improve outcomes like empowerment for this population. Despite this, psychiatric genetic counseling is not yet routinely or widely offered. This review describes the state of the evidence about the process and outcomes of psychiatric genetic counseling, focusing on its clinical implications and remaining research gaps.
Copyright © 2020 Cold Spring Harbor Laboratory Press; all rights reserved.

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Year:  2020        PMID: 31501264      PMCID: PMC7263094          DOI: 10.1101/cshperspect.a036608

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN: 2157-1422            Impact factor:   5.159


  42 in total

1.  Genetic counselling in family planning.

Authors:  P Kumar
Journal:  Antiseptic       Date:  1968-11

2.  Conceptualizing genetic counseling as psychotherapy in the era of genomic medicine.

Authors:  Jehannine Austin; Alicia Semaka; George Hadjipavlou
Journal:  J Genet Couns       Date:  2014-05-21       Impact factor: 2.537

3.  Self-Stigma in Relatives of people with Mental Illness scale: development and validation.

Authors:  E Morris; C Hippman; G Murray; E E Michalak; J E Boyd; J Livingston; A Inglis; P Carrion; J Austin
Journal:  Br J Psychiatry       Date:  2018-02-05       Impact factor: 9.319

4.  Genetic counselling for schizophrenia.

Authors:  A Reveley
Journal:  Br J Psychiatry       Date:  1985-08       Impact factor: 9.319

5.  Evaluating genetic counseling for individuals with schizophrenia in the molecular age.

Authors:  Gregory Costain; Mary Jane Esplen; Brenda Toner; Stephen W Scherer; Wendy S Meschino; Kathleen A Hodgkinson; Anne S Bassett
Journal:  Schizophr Bull       Date:  2012-12-12       Impact factor: 9.306

6.  Psychiatric genetic counselling for parents of individuals affected with psychotic disorders: a pilot study.

Authors:  Jehannine C Austin; William G Honer
Journal:  Early Interv Psychiatry       Date:  2008-05       Impact factor: 2.732

Review 7.  Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies.

Authors:  David T Miller; Margaret P Adam; Swaroop Aradhya; Leslie G Biesecker; Arthur R Brothman; Nigel P Carter; Deanna M Church; John A Crolla; Evan E Eichler; Charles J Epstein; W Andrew Faucett; Lars Feuk; Jan M Friedman; Ada Hamosh; Laird Jackson; Erin B Kaminsky; Klaas Kok; Ian D Krantz; Robert M Kuhn; Charles Lee; James M Ostell; Carla Rosenberg; Stephen W Scherer; Nancy B Spinner; Dimitri J Stavropoulos; James H Tepperberg; Erik C Thorland; Joris R Vermeesch; Darrel J Waggoner; Michael S Watson; Christa Lese Martin; David H Ledbetter
Journal:  Am J Hum Genet       Date:  2010-05-14       Impact factor: 11.025

8.  Genetic Counseling for Alcohol Addiction: Assessing Perceptions and Potential Utility in Individuals with Lived Experience and Their Family Members.

Authors:  Fayth M Kalb; Victoria Vincent; Teresa Herzog; Jehannine Austin
Journal:  J Genet Couns       Date:  2017-02-07       Impact factor: 2.537

9.  Implications of genetic risk information in families with a high density of bipolar disorder: an exploratory study.

Authors:  Bettina Meiser; Philip B Mitchell; H McGirr; M Van Herten; Peter R Schofield
Journal:  Soc Sci Med       Date:  2005-01       Impact factor: 4.634

10.  Patient perspectives on the process and outcomes of psychiatric genetic counseling: An "Empowering Encounter".

Authors:  Alicia Semaka; Jehannine Austin
Journal:  J Genet Couns       Date:  2019-05-03       Impact factor: 2.537

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  6 in total

1.  Psychiatric polygenic risk scores: Child and adolescent psychiatrists' knowledge, attitudes, and experiences.

Authors:  Stacey Pereira; Katrina A Muñoz; Brent J Small; Takahiro Soda; Laura N Torgerson; Clarissa E Sanchez; Jehannine Austin; Eric A Storch; Gabriel Lázaro-Muñoz
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2022-07-06       Impact factor: 3.358

2.  Teenagers and Precision Psychiatry: A Window of Opportunity.

Authors:  Maya Sabatello; Ying Chen; Carmen Fiorella Herrera; Erika Brockhoff; Jehannine Austin; Paul S Appelbaum
Journal:  Public Health Genomics       Date:  2021-01-27       Impact factor: 2.000

3.  In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.

Authors:  Jessica L Bourdon; Amelia Dorsey; Maia Zalik; Amanda Pietka; Patricia Salyer; Michael J Bray; Laura J Bierut; Alex T Ramsey
Journal:  BMC Med Genomics       Date:  2021-05-26       Impact factor: 3.063

4.  Ethical concerns relating to genetic risk scores for suicide.

Authors:  Anna Docherty; Brent Kious; Teneille Brown; Leslie Francis; Louisa Stark; Brooks Keeshin; Jeffrey Botkin; Emily DiBlasi; Doug Gray; Hilary Coon
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2021-09-01       Impact factor: 3.568

5.  Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores.

Authors:  Lasse Folkersen; Oliver Pain; Andrés Ingason; Thomas Werge; Cathryn M Lewis; Jehannine Austin
Journal:  Front Genet       Date:  2020-06-30       Impact factor: 4.599

6.  The stepwise process of integrating a genetic counsellor into primary care.

Authors:  Caitlin Slomp; Emily Morris; Morgan Price; Alison M Elliott; Jehannine Austin
Journal:  Eur J Hum Genet       Date:  2022-01-31       Impact factor: 5.351

  6 in total

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