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Literature DB >> 31481797

Nuclear actin filaments in DNA repair dynamics.

Christopher Patrick Caridi¹, Matthias Plessner^2,3, Robert Grosse^2,3, Irene Chiolo⁴.

Abstract

Recent development of innovative tools for live imaging of actin filaments (F-actin) enabled the detection of surprising nuclear structures responding to various stimuli, challenging previous models that actin is substantially monomeric in the nucleus. We review these discoveries, focusing on double-strand break (DSB) repair responses. These studies revealed a remarkable network of nuclear filaments and regulatory mechanisms coordinating chromatin dynamics with repair progression and led to a paradigm shift by uncovering the directed movement of repair sites.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：
Actins
Chromatin

Year: 2019 PMID： 31481797 PMCID： PMC6736642 DOI： 10.1038/s41556-019-0379-1

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

157 in total

Review 1. Regulation of actin filament assembly by Arp2/3 complex and formins.

Authors: Thomas D Pollard
Journal: Annu Rev Biophys Biomol Struct Date: 2007

Review 2. Actin visualization at a glance.

Authors: Michael Melak; Matthias Plessner; Robert Grosse
Journal: J Cell Sci Date: 2017-01-12 Impact factor: 5.285

3. Nuclear F-actin formation and reorganization upon cell spreading.

Authors: Matthias Plessner; Michael Melak; Pilar Chinchilla; Christian Baarlink; Robert Grosse
Journal: J Biol Chem Date: 2015-03-10 Impact factor: 5.157

Review 4. Actin assembly mechanisms at a glance.

Authors: Klemens Rottner; Jan Faix; Sven Bogdan; Stefan Linder; Eugen Kerkhoff
Journal: J Cell Sci Date: 2017-10-15 Impact factor: 5.285

Review 5. Actin and Actin-Binding Proteins.

Authors: Thomas D Pollard
Journal: Cold Spring Harb Perspect Biol Date: 2016-08-01 Impact factor: 10.005

Review 6. Myosin-Driven Intracellular Transport.

Authors: Margaret A Titus
Journal: Cold Spring Harb Perspect Biol Date: 2018-03-01 Impact factor: 10.005

7. Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

Authors: Christian Baarlink; Haicui Wang; Robert Grosse
Journal: Science Date: 2013-04-04 Impact factor: 47.728

8. Visualization of actin filaments and monomers in somatic cell nuclei.

Authors: Brittany J Belin; Beth A Cimini; Elizabeth H Blackburn; R Dyche Mullins
Journal: Mol Biol Cell Date: 2013-02-27 Impact factor: 4.138

9. DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected].

Authors: Brittany J Belin; Terri Lee; R Dyche Mullins
Journal: Elife Date: 2015-08-19 Impact factor: 8.140

10. Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities.

Authors: Jeffrey M Verboon; Bina Sugumar; Susan M Parkhurst
Journal: Nucleus Date: 2015 Impact factor: 4.197

29 in total

1. Arp2/3 and Unc45 maintain heterochromatin stability in Drosophila polytene chromosomes.

Authors: George Dialynas; Laetitia Delabaere; Irene Chiolo
Journal: Exp Biol Med (Maywood) Date: 2019-07-31

2. A role for keratin 17 during DNA damage response and tumor initiation.

Authors: Raji R Nair; Joshua Hsu; Justin T Jacob; Christopher M Pineda; Ryan P Hobbs; Pierre A Coulombe
Journal: Proc Natl Acad Sci U S A Date: 2021-03-30 Impact factor: 11.205

3. Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state.

Authors: Caterina Carraro; Lorenzo Bonaguro; Jonas Schulte-Schrepping; Arik Horne; Marie Oestreich; Stefanie Warnat-Herresthal; Tim Helbing; Michele De Franco; Kristian Haendler; Sach Mukherjee; Thomas Ulas; Valentina Gandin; Richard Goettlich; Anna C Aschenbrenner; Joachim L Schultze; Barbara Gatto
Journal: Elife Date: 2022-08-31 Impact factor: 8.713

Nuclear actin filaments in DNA repair dynamics.

Review 1. Regulation of actin filament assembly by Arp2/3 complex and formins.

Review 2. Actin visualization at a glance.

3. Nuclear F-actin formation and reorganization upon cell spreading.

Review 4. Actin assembly mechanisms at a glance.

Review 5. Actin and Actin-Binding Proteins.

Review 6. Myosin-Driven Intracellular Transport.

7. Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

8. Visualization of actin filaments and monomers in somatic cell nuclei.

9. DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected].

10. Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities.

1. Arp2/3 and Unc45 maintain heterochromatin stability in Drosophila polytene chromosomes.

2. A role for keratin 17 during DNA damage response and tumor initiation.

3. Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state.

4. SUMOylation of Nuclear γ-Actin by SUMO2 supports DNA Damage Repair against Myocardial Ischemia-Reperfusion Injury.

Review 5. The Self-Organizing Genome: Principles of Genome Architecture and Function.

Review 6. Polymer perspective of genome mobilization.

Review 7. Actin' between phase separated domains for heterochromatin repair.

8. Single Cell Label-Free Probing of Chromatin Dynamics During B Lymphocyte Maturation.

9. Live Cell Imaging of Nuclear Actin Filaments and Heterochromatic Repair foci in Drosophila and Mouse Cells.

Review 10. Low complexity domains, condensates, and stem cell pluripotency.