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Literature DB >> 31465950

Standardization of I-124 by three liquid scintillation-based methods.

D E Bergeron¹, J T Cessna², R Fitzgerald², L Pibida², B E Zimmerman².

Abstract

A solution of 124I was standardized for activity by 4πβ(LS)-γ(NaI) live-timed anticoincidence (LTAC) counting, with confirmatory measurements by triple-to-double coincidence ratio (TDCR) and CIEMAT-NIST efficiency tracing (CNET) liquid scintillation counting. The LTAC-based standard was shown to be in agreement (within k = 1 uncertainties) with previous measurements at NIST and elsewhere. Calibration settings for radionuclide calibrators were determined and a discrepancy with literature values, partially due to a calibration methodology dependent upon an erroneous setting for 18F, was identified and explained. Published by Elsevier Ltd.

Entities: Chemical Disease Gene Species

Keywords: Anticoincidence; Dose calibrator; Fluorine-18; Iodine-124; Liquid scintillation counting; Monte Carlo; Positron emission tomography; Quantitative imaging

Year: 2019 PMID： 31465950 PMCID： PMC6839768 DOI： 10.1016/j.apradiso.2019.108849

Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513

Keyword Cloud
References

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Authors: Brian E Zimmerman; Denis E Bergeron; Jeffrey T Cessna
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Standardization of I-124 by three liquid scintillation-based methods.

1. Software studies for germanium detectors data analysis.

2. A new NIST primary standardization of 18F.

3. Monte Carlo based approach to the LS–NaI 4πβ–γ anticoincidence extrapolation and uncertainty.

4. An automated ionization chamber for secondary radioactivity standards.

5. Impact of Recent Change in the National Institute of Standards and Technology Standard for 18F on the Relative Response of 68Ge-Based Mock Syringe Dose Calibrator Standards.

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