| Literature DB >> 31464582 |
Ayman El-Menyar1, Elizabeth Tilley2, Hassan Al-Thani3, Rifat Latifi4.
Abstract
BACKGROUND: Approximately one third of subjects ≥65 year old and half of subjects ≥80 years old sustain a fall injury each year. We aimed to study the outcomes of fall from a height (FFH) among older adults. We hypothesized that in an elderly population, fall-related injury and mortality are the same in both genders.Entities:
Keywords: Fall from height; Geriatrics; Injury severity; Mechanism of injury; Trauma in elderly
Mesh:
Year: 2019 PMID: 31464582 PMCID: PMC6716940 DOI: 10.1186/s12877-019-1252-6
Source DB: PubMed Journal: BMC Geriatr ISSN: 1471-2318 Impact factor: 3.921
Demographics, characteristics and outcomes based on age group in fall-related injured patients
| Variable | Age 60–69 | Age 70–79 | Age ≥ 80 |
|
|---|---|---|---|---|
| Total ( | 584(27%) | 570(26%) | 1027(47%) | |
| White ( | 450 (77.1%) | 456 (80.0%) | 920 (89.6%) | 0.001 |
| Black ( | 43 (7.4%) | 28 (4.9%) | 22 (2.1%) | |
| Hispanic ( | 48 (8.4%) | 29 (5.1%) | 39 (3.8%) | |
| Alcohol consumption ( | 38 (6.5%) | 34 (6.0%) | 43 (4.2%) | 0.001 |
| NISS* | 14.43, 12.0 (1–75) | 15.93, 12.0 (1–75) | 14.96, 12.0 (1–75) | 0.001 |
| ISS* | 10.82, 9.0, (1–75) | 11.99, 9.0, (1–75) | 11.73, 9.0, (1–50) | 0.001 |
| Shock index** | 0.62 ± 0.16 | 0.61 ± 0.19 | 0.60 ± 0.16 | 0.001 |
| TRISS** | 0.9258 ± 0.139 | 0.9085 ± 0.162 | 0.920 ± 0.141 | 0.001 |
| Year | ||||
| 2012 ( | 114 (19.5%) | 127 (22.3%) | 197 (19.2%) | 0.372 |
| 2013 ( | 119 (20.4%) | 115 (20.2%) | 214 (20.8%) | |
| 2014 ( | 125 (21.4%) | 114 (20.0%) | 191 (18.6%) | |
| 2015 ( | 115 (19.7%) | 97 (17.0%) | 205 (20.0%) | |
| 2016 (N = 448, 20.5%) | 111 (19.0%) | 117 (20.5%) | 220 (21.4%) | |
| Place of trauma | ||||
| Public ( | 32 (33.3%) | 15 (14.9%) | 16 (8.05) | 0.001 |
| Residence ( | 64 (66.7%) | 86 (85.1%) | 185 (92.0%) | |
| Fall Height in meter* | 8.67, 8.0, (1–40) | 7.69, 6.0, (1–30) | 5.45, 3.0, (1–40) | 0.001 |
| Glasgow coma scale | ||||
| Mild (> 12), | 531 (91.2%) | 506 (88.9%) | 920 (90.1%) | 0.243 |
| Moderate (8–12), | 17 (2.9%) | 19 (3.3%) | 40 (3.9%) | |
| Severe (< 8), | 34 (5.8%) | 44 (7.7%) | 61 (6.0%) | |
| Max AIS** | ||||
| Head | 3.03 (1.18) | 3.2 (1.22) | 3.06 (1.25) | 0.199 |
| Upper extremities | 1.89 (.56) | 1.87 (.54) | 1.77 (.57) | 0.040 |
| Lower extremities | 2.16 (.65) | 2.34 (.75) | 2.46 (.75) | 0.001 |
| Spine | 2.39 (.80) | 2.5 (.77) | 2.4 (.64) | 0.508 |
| Diabetes mellitus ( | 141 (24.1%) | 172 (30.2%) | 223 (21.7%) | 0.001 |
| Rib injury ( | 104 (17.8%) | 88 (15.4%) | 177 17.2%) | 0.001 |
| Blood Transfusion ( | 71 (13.5%) | 70 (13.6%) | 180 (19.3%) | 0.003 |
| Hospital stay, days* | 8.10, 5.0, (1–95) | 9.8, 6.0, (1–302) | 7.95, 6.0, (1–96) | 0.001 |
| Mortality ( | 5 (3.6%) | 11 (11.3%) | 12 (14%) | 0.001 |
* = mean, median and range. ** = mean and standard deviation, ***N = number of patients
patients characteristics based on the height of fall (n = 2181)
| Variable | < 1 m ( | 1-3 m ( | > 3-6 m ( | > 6 m ( |
|
|---|---|---|---|---|---|
| Female | 811 (56.4) | 171 (58.6) | 58 (44.6) | 92 (28.7) | 0.001 |
| Male | 627 (43.6) | 121 (41.4) | 72 (55.4) | 229 (71.3) | 0.001 |
| Age (years) ** | 79(60–103) | 81(60–102)* | 74 (60–99)* | 71 (60–98)* | 0.001 |
| ISS** | 10 (9.7–10.3) | 10.7 (9.9–11.5)* | 12.1 (10.9–13.3)* | 13.4 (12.8–14.1)* | 0.001 |
| NISS** | 13.2 (12.8–13.7) | 13.7 (12.7–14.8)* | 16.7 (15.1–18.3)* | 17.8 (16.9–18.7)* | 0.001 |
| Abdomen AIS** | 2.4 (2.2–2.6) | 2.1 (1.7–2.5) | 2.6 (2–3.2) | 2.2 (1.9–2.4)* | 0.235 |
| Head AIS** | 3.2 (3.1–3.3) | 3.1 (2.9–3.3) | 2.9 (2.7–3.1) | 2.8 (2.7–3)* | 0.001 |
| Thorax AIS** | 2.7 (2.6–2.8) | 2.6 (2.4–2.9) | 2.7 (2.5–3) | 2.7 (2.6–2.8) | 0.968 |
| Upper extremity AIS** | 1.8 (1.8–1.9) | 1.9 (1.7–2) | 2 (1.8–2.1) | 1.9 (1.9–2) | 0.044 |
| Spine AIS** | 2.5 (2.4–2.6) | 2.5 (2.3–2.6) | 2.5 (2.2–2.7) | 2.3 (2.3–2.4)* | 0.013 |
| Lower extremity AIS** | 2.4 (2.3–2.4) | 2.5 (2.4–2.6) | 2 (1.9–2.2)* | 2 (1.9–2.1)* | 0.001 |
| Probability of survival (TRISS) ** | 0.94 (0.93–0.94) | 0.94 (0.92–0.95) | 0.93 (0.91–0.95) | 0.93 (0.92–0.94) | 0.069 |
| Hospital stay, days | 7.7 (7.2–8.1) | 7.9 (7–8.8) | 7.8 (6.6–9) | 8.1 (7.5–8.7) | 0.800 |
| Mortality | 127 (8.8%) | 18 (6.2%) | 9 (6.9%) | 28 (8.7%) | 0.44 |
* Post hoc Bonferroni test significant (p < 0.05) and reference group is < 1 m height of fall,** = median, range. AIS = abbreviated injury score, ISS: injury severity score, NISS = new ISS, TRISS = Trauma and injury severity score
Fig. 1Study design and breakdown of Fall-related injury and mortality in each age group and gender
comparison between females and males aged > 60 years old
| Variable | Females | Males |
|
|---|---|---|---|
| Person aged > 80 years | 4.8% | 7.2% | 0.37 |
| NISS score | 13.5 ± 10 | 16.7 ± 12.6 | 0.001 |
| ISS category | |||
| 16–24 | 16% | 20% | 0.001for all |
| > 24 | 6% | 13% | |
| GCS category | |||
| 8–12 | 2.6% | 4.5% | 0.002 for all |
| < 8 | 4.7% | 8.4% | |
| Max AIS head > 2 | 67% | 73% | 0.09 |
| Alcohol consumption (% of persons) | 4.2% | 6.2% | 0.02 |
| Smoking | 4% | 8.7% | 0.001 |
| Diabetes mellitus | 22.8% | 26.4% | 0.05 |
| Rib fractures | 13% | 21% | 0.001 |
| Fall heights median (IQR) | < 1(< 1–3) | 3(< 1–6) | 0.02 |
| Mortality | 5.2% | 12.4% | 0.001 |
IQR = interquartile range
patients characteristics and outcomes within each gender based on the age groups (< vs > 65 years)
| Variable | Females ( | Males ( | ||||
|---|---|---|---|---|---|---|
| < 65 yrs | > 65 yrs |
| < 65 yrs | > 65 yrs |
| |
| Patients number | 488(32.3%) | 1022(67.7%) | 0.001 | 1300(60.3%) | 855(39.7%) | 0.001 |
| Mean age ± SD | 27 ± 22 | 81 ± 9.0 | 0.001 | 31 ± 20 | 78 ± 8.0 | 0.001 |
| ISSa score | 5(4–9) | 9(5–14) | 0.001 | 9(4–13) | 10(8–17) | 0.001 |
| NISSa score | 8(4–12) | 10(9–17) | 0.001 | 9(4–17) | 13(9–22) | 0.001 |
| TRISSa score | 0.994(0.983–0.996) | 0.968(0.943–0.975) | 0.001 | 0.994(0.983–0.996) | 0.965(0.933–0.970) | 0.001 |
| Fall heighta in meter | 4(3–9.5) | 3(3–8) | 0.004 | 8(4–15) | 6(3–11) | 0.001 |
| Diabetes mellitus | 6.3% | 23.3% | 0.001 | 6.9% | 26.8% | 0.001 |
| Rib fractures | 4.2% | 13.5% | 0.001 | 11% | 20% | 0.001 |
| GCS ≤ 8 | 4.3% | 5.6% | 0.17 | 5.7% | 8.9% | 0.002 |
| Person received blood transfusion | 4.1% | 15.6% | 0.001 | 5.2% | 18.1% | 0.001 |
| Mortality | 8(1.6%) | 56(5.5%) | 0.001 | 32(2.5%) | 116(13.6%) | 0.001 |
aData presented as median (interquartile range)
predictors of mortality in patients with fall-related injury
| Variable | Odd ratio | 95% CI |
| |
|---|---|---|---|---|
| Age | 1.059 | 1.035 | 1.085 | 0.001 |
| Fall height | 0.924 | 0.877 | 0.973 | 0.003 |
| Injury Severity Score | 1.123 | 1.094 | 1.153 | 0.001 |
| Sex (male) | 2.70 | 1.69 | 4.16 | 0.001 |
| Diabetes mellitus | 1.253 | 0.769 | 2.041 | 0.366 |
| Blood Transfusion | 1.455 | 0.915 | 2.314 | 0.113 |
| Glasgow Coma scale | 0.814 | 0.772 | 0.858 | 0.001 |
| Shock Index | 3.796 | 1.271 | 11.331 | 0.017 |