Literature DB >> 31425068

Analytic Determination of Rectangular-Pinhole Sensitivity With Penetration.

Scott D Metzler, Stephen C Moore.   

Abstract

Modern small-animal SPECT systems use multiple pinhole collimators per detector to increase sensitivity while still maintaining high resolution. This resolution is a combination of aperture resolution combined with detector resolution, which is mitigated by magnification. Higher magnification results in better resolution, but fewer apertures per detector. When multiple pinhole collimators project onto the same detector, those with a rectangular field of view (FOV) can be packed more tightly than those with a circular FOV. In addition, a rectangular aperture can be used to obtain different resolution-sensitivity tradeoffs in the two orthogonal directions. Thus, these rectangular-pinhole collimators can have independent FOVs and independent resolution values in the two directions of the rectangular aperture. Previous work has determined the amount of penetration for circular pinholes (i.e., circular apertures with circular FOVs), where the pinhole walls were modeled as cones. In this work, a formula for the penetrative sensitivity for rectangular apertures with a rectangular FOV is determined. The formula was validated using numerical calculations for various combinations of acceptance angles, aperture sizes, linear attenuation coefficients, and incidence angles.

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Year:  2019        PMID: 31425068      PMCID: PMC7241287          DOI: 10.1109/TMI.2019.2936187

Source DB:  PubMed          Journal:  IEEE Trans Med Imaging        ISSN: 0278-0062            Impact factor:   10.048


  24 in total

1.  Analytic determination of pinhole collimator sensitivity with penetration.

Authors:  S D Metzler; J E Bowsher; M F Smith; R J Jaszczak
Journal:  IEEE Trans Med Imaging       Date:  2001-08       Impact factor: 10.048

2.  Pinhole collimation for ultra-high-resolution, small-field-of-view SPECT.

Authors:  R J Jaszczak; J Li; H Wang; M R Zalutsky; R E Coleman
Journal:  Phys Med Biol       Date:  1994-03       Impact factor: 3.609

3.  Characterization of a SPECT pinhole collimator for optimal detector usage (the lofthole).

Authors:  Karel Deprez; Lara R V Pato; Stefaan Vandenberghe; Roel Van Holen
Journal:  Phys Med Biol       Date:  2013-01-21       Impact factor: 3.609

4.  Quantitative imaging of iodine-131 distributions in brain tumors with pinhole SPECT: a phantom study.

Authors:  M F Smith; D R Gilland; R E Coleman; R J Jaszczak
Journal:  J Nucl Med       Date:  1998-05       Impact factor: 10.057

5.  U-SPECT-I: a novel system for submillimeter-resolution tomography with radiolabeled molecules in mice.

Authors:  Freek J Beekman; Frans van der Have; Brendan Vastenhouw; Annemarie J A van der Linden; Peter P van Rijk; J Peter H Burbach; Marten P Smidt
Journal:  J Nucl Med       Date:  2005-07       Impact factor: 10.057

6.  Pinhole imaging of gamma rays.

Authors:  D Paix
Journal:  Phys Med Biol       Date:  1967-10       Impact factor: 3.609

7.  Effect of pinhole shape on projection resolution.

Authors:  L C Johnson; S C Moore; S D Metzler
Journal:  Phys Med Biol       Date:  2016-02-19       Impact factor: 3.609

8.  Physical and clinical evaluation of high-resolution thyroid pinhole tomography.

Authors:  P M Wanet; A Sand; J Abramovici
Journal:  J Nucl Med       Date:  1996-12       Impact factor: 10.057

9.  Quantitative imaging of myocardial infarct in rats with high resolution pinhole SPECT.

Authors:  Paul D Acton; Daniel Thomas; Rong Zhou
Journal:  Int J Cardiovasc Imaging       Date:  2006-03-04       Impact factor: 2.357

10.  High-resolution clustered pinhole (131)Iodine SPECT imaging in mice.

Authors:  Frans van der Have; Oleksandra Ivashchenko; Marlies C Goorden; Ruud M Ramakers; Freek J Beekman
Journal:  Nucl Med Biol       Date:  2016-06-01       Impact factor: 2.408

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  1 in total

1.  Design Study of an Ultrahigh Resolution Brain SPECT System Using a Synthetic Compound-Eye Camera Design With Micro-Slit and Micro-Ring Apertures.

Authors:  Elena Maria Zannoni; Can Yang; Ling-Jian Meng
Journal:  IEEE Trans Med Imaging       Date:  2021-11-30       Impact factor: 10.048

  1 in total

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