Literature DB >> 3141794

The yeast regulatory protein ADR1 binds in a zinc-dependent manner to the upstream activating sequence of ADH2.

A Eisen1, W E Taylor, H Blumberg, E T Young.   

Abstract

The yeast ADR1 protein contains two zinc finger domains that are essential for its role in transcriptional activation of alcohol dehydrogenase (ADH2). These domains are thought to function as DNA-binding structures. An ADR1-beta-galactosidase fusion protein made in Escherichia coli and containing the finger domains of ADR1 binds in vitro in a zinc-dependent manner to DNA fragments containing the two ADH2 upstream activation sequences. The strongest binding is to upstream activation sequence 1, a 22-base-pair palindrome.

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Year:  1988        PMID： 3141794      PMCID： PMC365534          DOI： 10.1128/mcb.8.10.4552-4556.1988

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  27 in total

1.  Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes.

Authors:  D R Engelke; S Y Ng; B S Shastry; R G Roeder
Journal:  Cell       Date:  1980-03       Impact factor: 41.582

Review 2.  Protein-DNA recognition.

Authors:  C O Pabo; R T Sauer
Journal:  Annu Rev Biochem       Date:  1984       Impact factor: 23.643

3.  Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator.

Authors:  J Anderson; M Ptashne; S C Harrison
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

4.  The primary structure of transcription factor TFIIIA has 12 consecutive repeats.

Authors:  R S Brown; C Sander; P Argos
Journal:  FEBS Lett       Date:  1985-07-08       Impact factor: 4.124

5.  The operator-binding domain of lambda repressor: structure and DNA recognition.

Authors:  C O Pabo; M Lewis
Journal:  Nature       Date:  1982-07-29       Impact factor: 49.962

6.  Structure of the cro repressor from bacteriophage lambda and its interaction with DNA.

Authors:  W F Anderson; D H Ohlendorf; Y Takeda; B W Matthews
Journal:  Nature       Date:  1981-04-30       Impact factor: 49.962

7.  Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses.

Authors:  R P Hertzberg; P B Dervan
Journal:  Biochemistry       Date:  1984-08-14       Impact factor: 3.162

8.  Xenopus transcription factor A requires zinc for binding to the 5 S RNA gene.

Authors:  J S Hanas; D J Hazuda; D F Bogenhagen; F Y Wu; C W Wu
Journal:  J Biol Chem       Date:  1983-12-10       Impact factor: 5.157

9.  Regulation of expression and activity of the yeast transcription factor ADR1.

Authors:  H Blumberg; T A Hartshorne; E T Young
Journal:  Mol Cell Biol       Date:  1988-05       Impact factor: 4.272

10.  A vector that uses phage signals for efficient synthesis of proteins in Escherichia coli.

Authors:  C Queen
Journal:  J Mol Appl Genet       Date:  1983
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  41 in total

1.  Histone acetylation at promoters is differentially affected by specific activators and repressors.

Authors:  J Deckert; K Struhl
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

2.  Identification and characterization of three genes that affect expression of ADH2 in Saccharomyces cerevisiae.

Authors:  L Karnitz; M Morrison; E T Young
Journal:  Genetics       Date:  1992-10       Impact factor: 4.562

3.  A mutation outside the two zinc fingers of ADR1 can suppress defects in either finger.

Authors:  S Camier; N Kacherovsky; E T Young
Journal:  Mol Cell Biol       Date:  1992-12       Impact factor: 4.272

Review 4.  Sp1 and the subfamily of zinc finger proteins with guanine-rich binding sites.

Authors:  J M Berg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

5.  Toward rules relating zinc finger protein sequences and DNA binding site preferences.

Authors:  J R Desjarlais; J M Berg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

6.  Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

Authors:  X M Cao; R A Koski; A Gashler; M McKiernan; C F Morris; R Gaffney; R V Hay; V P Sukhatme
Journal:  Mol Cell Biol       Date:  1990-05       Impact factor: 4.272

7.  Adjacent upstream activation sequence elements synergistically regulate transcription of ADH2 in Saccharomyces cerevisiae.

Authors:  J Yu; M S Donoviel; E T Young
Journal:  Mol Cell Biol       Date:  1989-01       Impact factor: 4.272

8.  DNA binding site specificity of the Neurospora global nitrogen regulatory protein NIT2: analysis with mutated binding sites.

Authors:  T Y Chiang; R Rai; T G Cooper; G A Marzluf
Journal:  Mol Gen Genet       Date:  1994-11-15

9.  A carbon source-responsive promoter element necessary for activation of the isocitrate lyase gene ICL1 is common to genes of the gluconeogenic pathway in the yeast Saccharomyces cerevisiae.

Authors:  A Schöler; H J Schüller
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

10.  Identification of potential target genes for Adr1p through characterization of essential nucleotides in UAS1.

Authors:  C Cheng; N Kacherovsky; K M Dombek; S Camier; S K Thukral; E Rhim; E T Young
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272
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