Literature DB >> 7088190

The operator-binding domain of lambda repressor: structure and DNA recognition.

C O Pabo, M Lewis.   

Abstract

The structure of the operator-binding domain of the lambda repressor has been determined at 3.2 A resolution. This domain contains an extended N-terminal arm and five alpha-helices. Model-building studies of the repressor-operator complex suggest that alpha-helices, especially the N-terminal parts of these helices, may provide a useful surface for protein-DNA interactions.

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Year:  1982        PMID： 7088190     DOI： 10.1038/298443a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  125 in total

1.  Thermodynamics of specific and nonspecific DNA binding by two DNA-binding domains conjugated to fluorescent probes.

Authors:  M Thompson; N W Woodbury
Journal:  Biophys J       Date:  2001-09       Impact factor: 4.033

2.  Retroevolution of lambda Cro toward a stable monomer.

Authors:  Kelly R LeFevre; Matthew H J Cordes
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-21       Impact factor: 11.205

3.  A mutation outside the two zinc fingers of ADR1 can suppress defects in either finger.

Authors:  S Camier; N Kacherovsky; E T Young
Journal:  Mol Cell Biol       Date:  1992-12       Impact factor: 4.272

4.  Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.

Authors:  Lisheng Ni; Weijun Xu; Muthiah Kumaraswami; Maria A Schumacher
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-04       Impact factor: 11.205

5.  Atomistic folding simulations of the five-helix bundle protein λ(6−85).

Authors:  Gregory R Bowman; Vincent A Voelz; Vijay S Pande
Journal:  J Am Chem Soc       Date:  2011-02-02       Impact factor: 15.419

Review 6.  Origins of specificity in protein-DNA recognition.

Authors:  Remo Rohs; Xiangshu Jin; Sean M West; Rohit Joshi; Barry Honig; Richard S Mann
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

7.  Nucleotide sequence binding specificity of the LexA repressor of Escherichia coli K-12.

Authors:  K F Wertman; D W Mount
Journal:  J Bacteriol       Date:  1985-07       Impact factor: 3.490

8.  Defining a bacteriophage T4 late promoter: bacteriophage T4 gene 55 protein suffices for directing late promoter recognition.

Authors:  G A Kassavetis; E P Geiduschek
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

9.  Cloning and sequence analysis of a chymotrypsinlike protease from Treponema denticola.

Authors:  S Arakawa; H K Kuramitsu
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

10.  Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.

Authors:  I T Weber; T A Steitz
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205
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