Literature DB >> 3141793

Efficiency of translation initiation by non-AUG codons in Saccharomyces cerevisiae.

J M Clements1, T M Laz, F Sherman.   

Abstract

The quantitative levels of initiation of protein synthesis at codons other than AUG were determined with a CYC7-lacZ fused gene in the yeast Saccharomyces cerevisiae. AUG was the only codon which efficiently initiated translation, although some non-AUG codons allowed initiation at very low efficiency, below 1% of the normal level. Since translation initiates at codons other than AUG in at least two wild-type genes from eucaryotes, other factors presumably play a role in enhancing the activity of non-AUG codons.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3141793      PMCID： PMC365530          DOI： 10.1128/mcb.8.10.4533-4536.1988

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  24 in total

1.  Primary structure of a methionine transfer RNA from Escherichia coli.

Authors:  S Cory; K A Marcker; S K Dube; B F Clark
Journal:  Nature       Date:  1968-12-07       Impact factor: 49.962

2.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

3.  An extensive deletion causing overproduction of yeast iso-2-cytochrome c.

Authors:  G L McKnight; T S Cardillo; F Sherman
Journal:  Cell       Date:  1981-08       Impact factor: 41.582

4.  Beta-galactosidase gene fusions for analyzing gene expression in escherichia coli and yeast.

Authors:  M J Casadaban; A Martinez-Arias; S K Shapira; J Chou
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

5.  AUG is the only initiation codon in eukaryotes.

Authors:  F Sherman; G McKnight; J W Stewart
Journal:  Biochim Biophys Acta       Date:  1980-09-19

6.  Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

Authors:  R Ng; J Abelson
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

7.  Mutational analysis of a regulatory region in bacteriophage lambda that has overlapping signals for the initiation of transcription and translation.

Authors:  D L Wulff; M Mahoney; A Shatzman; M Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

8.  The nucleotide sequence of the cloned tufA gene of Escherichia coli.

Authors:  T Yokota; H Sugisaki; M Takanami; Y Kaziro
Journal:  Gene       Date:  1980-12       Impact factor: 3.688

9.  mRNA structures influencing translation in the yeast Saccharomyces cerevisiae.

Authors:  S B Baim; F Sherman
Journal:  Mol Cell Biol       Date:  1988-04       Impact factor: 4.272

Review 10.  Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

Authors:  M Kozak
Journal:  Microbiol Rev       Date:  1983-03
View more
  37 in total

1.  Non-AUG initiation of AGAMOUS mRNA translation in Arabidopsis thaliana.

Authors:  J L Riechmann; T Ito; E M Meyerowitz
Journal:  Mol Cell Biol       Date:  1999-12       Impact factor: 4.272

2.  Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1).

Authors:  Ivaylo P Ivanov; Gary Loughran; Matthew S Sachs; John F Atkins
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

3.  cis- and trans-acting suppressors of a translation initiation defect at the cyc1 locus of Saccharomyces cerevisiae.

Authors:  I Pinto; J G Na; F Sherman; M Hampsey
Journal:  Genetics       Date:  1992-09       Impact factor: 4.562

4.  The role of promoter elements of a ribosomal protein gene in Saccharomyces cerevisiae under various physiological conditions.

Authors:  S M Papciak; N J Pearson
Journal:  Mol Gen Genet       Date:  1992-07

5.  Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes.

Authors:  M Kozak
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

Review 6.  Eucaryotic codes.

Authors:  F Caron
Journal:  Experientia       Date:  1990-12-01

7.  Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast.

Authors:  Amy R Eisenberg; Andrea L Higdon; Ina Hollerer; Alexander P Fields; Irwin Jungreis; Paige D Diamond; Manolis Kellis; Marko Jovanovic; Gloria A Brar
Journal:  Cell Syst       Date:  2020-07-24       Impact factor: 10.304

8.  Translation initiation by non-AUG codons in Arabidopsis thaliana transgenic plants.

Authors:  Annie Depeiges; Fabienne Degroote; Marie Claude Espagnol; Georges Picard
Journal:  Plant Cell Rep       Date:  2005-09-24       Impact factor: 4.570

9.  Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation.

Authors:  Sarah E Kolitz; Julie E Takacs; Jon R Lorsch
Journal:  RNA       Date:  2008-11-24       Impact factor: 4.942

10.  A novel method for efficient expression cloning of fungal enzyme genes.

Authors:  H Dalbøge; H P Heldt-Hansen
Journal:  Mol Gen Genet       Date:  1994-05-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.