Jin-Wook Jung1,2, Chi-Hyeon Yoo1, Kyu-Ho Song3, Bo-Young Choe4. 1. Department of Biomedicine & Health Sciences and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Banpo-Daero, Seocho-Gu, Seoul, 137-701, Republic of Korea. 2. Department of Radiology, Seoul National University Hospital, Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea. 3. Biomedical MR Laboratory, Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO, USA. 4. Department of Biomedicine & Health Sciences and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Banpo-Daero, Seocho-Gu, Seoul, 137-701, Republic of Korea. bychoe@catholic.ac.kr.
Abstract
BACKGROUND: Knowledge of ovarian volume is important for diagnostic evaluations; however, normal ovarian volume studies on children and adolescents are lacking. OBJECTIVE: This study aimed to analyze age-specific ovarian volume and identify the diverse factors that contribute to ovarian diagnoses. MATERIALS AND METHODS: We retrospectively enrolled 180 patients (0-18 years of age) with normal ovaries who underwent magnetic resonance imaging (MRI) between 2010 and 2018. MRI sequences included coronal and axial T2-weighted turbo spin echo (TSE) images and coronal T1-weighted TSE images. Ovarian volume was calculated by the standard ellipsoid formula. Age-specific ovarian volume, height, weight, height-adjusted total ovarian volume and body mass index were obtained. Linear regression analysis was used to predict ovarian volume. RESULTS: Six age groups (infant; early and late child, and early, middle and late adolescent) were described. The early adolescent group (10-12 years) had the highest rate of increase. In the middle adolescent period (13-15 years), the curve of ovarian volume appeared flat. CONCLUSION: Our findings provide age-specific references for ovarian volume.
BACKGROUND: Knowledge of ovarian volume is important for diagnostic evaluations; however, normal ovarian volume studies on children and adolescents are lacking. OBJECTIVE: This study aimed to analyze age-specific ovarian volume and identify the diverse factors that contribute to ovarian diagnoses. MATERIALS AND METHODS: We retrospectively enrolled 180 patients (0-18 years of age) with normal ovaries who underwent magnetic resonance imaging (MRI) between 2010 and 2018. MRI sequences included coronal and axial T2-weighted turbo spin echo (TSE) images and coronal T1-weighted TSE images. Ovarian volume was calculated by the standard ellipsoid formula. Age-specific ovarian volume, height, weight, height-adjusted total ovarian volume and body mass index were obtained. Linear regression analysis was used to predict ovarian volume. RESULTS: Six age groups (infant; early and late child, and early, middle and late adolescent) were described. The early adolescent group (10-12 years) had the highest rate of increase. In the middle adolescent period (13-15 years), the curve of ovarian volume appeared flat. CONCLUSION: Our findings provide age-specific references for ovarian volume.
Entities:
Keywords:
Adolescents; Children; Height-adjusted total ovarian volume; Magnetic resonance imaging; Normal measurements; Ovarian volume; Ovary
Authors: Henrik Leonhardt; Mikael Hellström; Berit Gull; Anna-Karin Lind; Lars Nilsson; Per Olof Janson; Elisabet Stener-Victorin Journal: Fertil Steril Date: 2014-03-21 Impact factor: 7.329