Literature DB >> 31287739

Ambient neutron and photon dose equivalent H*(10) around a pencil beam scanning proton therapy facility.

Dayananda Shamurailatpam Sharma1, Kartikeswar Ch Patro1, Noufal Manthala Padannayel1, Manikandan Arjunan1, Ganapathy Krishnan1, Rajesh Thiyagarajan1, Srinivas Chilukuri2, Rakesh Jalali2.   

Abstract

OBJECTIVES: To measure leakage ambient dose equivalent H*(10) from stray secondary neutron and photon radiation around proton therapy (PT) facility and evaluate adequacy of shielding design. METHODS AND MATERIALS: H*(10) measurement were carried out at 149 locations around cyclotron vault (CV), beam transport system (BTS) and first treatment room (GTR3) of a multiroom PT facility using WENDI-II and SmartIon survey meter. Measurement were performed under extreme case scenarios wherein maximum secondary neutrons and photons were produced around CV, BTS and GTR3 by stopping 230MeV proton of 300nA on beam degrader, end of BTS and isocenter of GTR3. Weekly time average dose rate (TADR) were calculated from H*(10) value measured at selective hot spots by irradiating actual treatment plans of mix clinical sites.
RESULTS: The maximum total H*(10) were within 2 µSv/hr around CV, 5 µSv/hr around outer wall of BTS which increases up to 62 µSv/hr at the end of inside BTS corridor. Maximum H*(10) of 20.8 µSv/hr in treatment control console (P125), 23.4 µSv/hr behind the common wall between GTR3 and GTR2 (P132) and 25.7 µSv/hr above isocenter (P99) were observed around GTR3. Reduction of beam current from 6 to 3 nA and 1 nA at nozzle exit lead to decrease in total H*(10) at P125 from 20.8 to 11.35 and 4.62 µSv/hr. In comparison to extreme case scenario, H*(10) value at P125, P132 and P99 from clinically relevant irradiation parameters were reduce by a factor ranging from 8.6 for high range cube to 46.4 for brain clinical plan. The maximum weekly TADR per fraction was highest for large volume, sacral chordoma patient at 8.5 µSv/hr compare to 0.3 µSv/hr for brain patient. The calculated weekly TADR for 30 mix clinical cases and 15 fractions of 1 L cube resulted total weekly TADR of 83-84 µSv/hr at P125, P132 and P99. The maximum annual dose level at these hot spots were estimated at 4.37 mSv/Yr.
CONCLUSION: We have carried out an extensive measurement of H*(10) under different conditions. The shielding thickness of our PT facility is adequate to limit the dose to occupational worker and general public within the permissible stipulated limit. The data reported here can bridge the knowledge gap in ambient dose around PT facility and can also be used as a reference for any new and existing proton facility for intercomparison and validation. ADVANCES IN KNOWLEDGE: First extensive investigation of neutron and photon H*(10) around PT facility and can bridge the knowledge gap on ambient dose.

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Year:  2019        PMID: 31287739      PMCID: PMC6774605          DOI: 10.1259/bjr.20190382

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  10 in total

1.  Neutron shielding calculations in a proton therapy facility based on Monte Carlo simulations and analytical models: criterion for selecting the method of choice.

Authors:  U Titt; W D Newhauser
Journal:  Radiat Prot Dosimetry       Date:  2005       Impact factor: 0.972

Review 2.  Are further studies needed to justify the use of proton therapy for paediatric cancers of the central nervous system? A review of current evidence.

Authors:  Myxuan Huynh; Loredana Gabriela Marcu; Eileen Giles; Michala Short; Donna Matthews; Eva Bezak
Journal:  Radiother Oncol       Date:  2019-01-28       Impact factor: 6.280

3.  Measurement of neutron ambient dose equivalent in passive carbon-ion and proton radiotherapies.

Authors:  Shunsuke Yonai; Naruhiro Matsufuji; Tatsuaki Kanai; Yuki Matsui; Kaoru Matsushita; Haruo Yamashita; Masumi Numano; Takeji Sakae; Toshiyuki Terunuma; Teiji Nishio; Ryosuke Kohno; Takashi Akagi
Journal:  Med Phys       Date:  2008-11       Impact factor: 4.071

4.  Neutron H*(10) inside a proton therapy facility: comparison between Monte Carlo simulations and WENDI-2 measurements.

Authors:  V De Smet; F Stichelbaut; T Vanaudenhove; G Mathot; G De Lentdecker; A Dubus; N Pauly; I Gerardy
Journal:  Radiat Prot Dosimetry       Date:  2013-11-19       Impact factor: 0.972

5.  Measurement of stray radiation within a scanning proton therapy facility: EURADOS WG9 intercomparison exercise of active dosimetry systems.

Authors:  J Farah; V Mares; M Romero-Expósito; S Trinkl; C Domingo; V Dufek; M Klodowska; J Kubancak; Ž Knežević; M Liszka; M Majer; S Miljanić; O Ploc; K Schinner; L Stolarczyk; F Trompier; M Wielunski; P Olko; R M Harrison
Journal:  Med Phys       Date:  2015-05       Impact factor: 4.071

6.  WENDI: an improved neutron rem meter.

Authors:  R H Olsher; H H Hsu; A Beverding; J H Kleck; W H Casson; D G Vasilik; R T Devine
Journal:  Health Phys       Date:  2000-08       Impact factor: 1.316

Review 7.  The physics of proton therapy.

Authors:  Wayne D Newhauser; Rui Zhang
Journal:  Phys Med Biol       Date:  2015-03-24       Impact factor: 3.609

8.  Neutron production from beam-modifying devices in a modern double scattering proton therapy beam delivery system.

Authors:  Angélica Pérez-Andújar; Wayne D Newhauser; Paul M Deluca
Journal:  Phys Med Biol       Date:  2009-01-16       Impact factor: 3.609

9.  Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions.

Authors:  U Titt; N Sahoo; X Ding; Y Zheng; W D Newhauser; X R Zhu; J C Polf; M T Gillin; R Mohan
Journal:  Phys Med Biol       Date:  2008-07-31       Impact factor: 3.609

Review 10.  Charged particle therapy--optimization, challenges and future directions.

Authors:  Jay S Loeffler; Marco Durante
Journal:  Nat Rev Clin Oncol       Date:  2013-05-21       Impact factor: 66.675

  10 in total
  1 in total

1.  The Role of Plan Robustness Evaluation in Comparing Protons and Photons Plans - An Application on IMPT and IMRT Plans in Skull Base Chordomas.

Authors:  Manthala Padannayil Noufal; Lamberto Widesott; Shamurailatpam Dayananda Sharma; Roberto Righetto; Marco Cianchetti; Marco Schwarz
Journal:  J Med Phys       Date:  2021-02-02
  1 in total

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