Literature DB >> 31270725

Increased age adversely affects the therapeutic effect of CPAP treatment for olfactory functions.

Ayse Secil Dinc1, Melih Cayonu2, Sezgi Sahin Duyar3, Selma Fırat3.   

Abstract

PURPOSE: The aim of this study was to compare olfactory functions pre- and post-CPAP treatment in patients with moderate to severe OSA, and to evaluate the factors that cause changes in olfactory functions.
METHODS: Twenty-two patients who had completed regular usage of CPAP treatment for 2 months were included in this prospective study. Olfactory tests using Sniffin' Sticks were performed pre- and post-treatment.
RESULTS: The mean age of the subjects was 47.6 ± 9.5 years. We did not find a significant change in olfactory functions after 2 months of CPAP treatment in our study group. When the patients were divided into two groups-those whose olfactory functions showed improvement and those whose functions did not-it was found that the mean age of the patients whose olfactory functions did not improve was significantly higher statistically. A significant adverse correlation was found between age and post-treatment olfactory functions, specifically in odour threshold and odour identification scores.
CONCLUSIONS: Increased age adversely affects the therapeutic effect of CPAP treatment for olfactory functions.

Entities:  

Keywords:  Nasal continuous positive airway pressure; Obstructive sleep apnoea; Olfaction disorders; Polysomnography

Year:  2019        PMID: 31270725     DOI: 10.1007/s11325-019-01889-1

Source DB:  PubMed          Journal:  Sleep Breath        ISSN: 1520-9512            Impact factor:   2.816


  28 in total

1.  Sniffin'Sticks: a new olfactory test battery.

Authors:  M Wolfensberger; I Schnieper; A Welge-Lüssen
Journal:  Acta Otolaryngol       Date:  2000-03       Impact factor: 1.494

2.  Olfaction and emotion: the case of autobiographical memory.

Authors:  Johan Willander; Maria Larsson
Journal:  Mem Cognit       Date:  2007-10

3.  'Sniffin' sticks': olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold.

Authors:  T Hummel; B Sekinger; S R Wolf; E Pauli; G Kobal
Journal:  Chem Senses       Date:  1997-02       Impact factor: 3.160

4.  Does positive airway pressure therapy improve olfactory function?

Authors:  Sabri Koseoğlu; Serhan Derin; Mustafa Yilmaz; Gulnihal Kutlu; Murat Sahan
Journal:  Int Forum Allergy Rhinol       Date:  2017-03-08       Impact factor: 3.858

5.  Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects.

Authors:  T Hummel; G Kobal; H Gudziol; A Mackay-Sim
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-09-23       Impact factor: 2.503

Review 6.  Neurocognitive effects of obstructive sleep apnea syndrome.

Authors:  Edwin Verstraeten
Journal:  Curr Neurol Neurosci Rep       Date:  2007-03       Impact factor: 5.081

7.  Nasal cytology: a marker of clinically silent inflammation in patients with obstructive sleep apnea and a predictor of noncompliance with nasal CPAP therapy.

Authors:  Farhad F Shadan; Alfredo A Jalowayski; John Fahrenholz; Lawrence E Kline; Arthur Dawson
Journal:  J Clin Sleep Med       Date:  2005-07-15       Impact factor: 4.062

8.  Clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea.

Authors:  Clete A Kushida; Alejandro Chediak; Richard B Berry; Lee K Brown; David Gozal; Conrad Iber; Sairam Parthasarathy; Stuart F Quan; James A Rowley
Journal:  J Clin Sleep Med       Date:  2008-04-15       Impact factor: 4.062

9.  Correlation between olfactory bulb volume and olfactory function.

Authors:  D Buschhüter; M Smitka; S Puschmann; J C Gerber; M Witt; N D Abolmaali; T Hummel
Journal:  Neuroimage       Date:  2008-05-10       Impact factor: 6.556

10.  Significant improvement of olfactory performance in sleep apnea patients after three months of nasal CPAP therapy - Observational study and randomized trial.

Authors:  Bettina Boerner; Gabrielo M Tini; Patrick Fachinger; Sereina M Graber; Sarosh Irani
Journal:  PLoS One       Date:  2017-02-03       Impact factor: 3.240

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