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Literature DB >> 3122027

Transfection of an immunoglobulin kappa gene into mature human B lymphocytes.

Abstract

We show in this report that the transcription induced by interleukin-2 or pokeweed mitogens of the kappa MOPC 41 immunoglobulin light-chain gene transfected into primary human or murine B lymphocytes initiates from a previously unobserved start site about 26 base pairs upstream of the start site used in myeloma cell lines.

Entities: Disease Species

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Year: 1988 PMID： 3122027 PMCID： PMC363164 DOI： 10.1128/mcb.8.1.511-513.1988

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

15 in total

1. A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation.

Authors: J G Seidman; E E Max; P Leder
Journal: Nature Date: 1979-08-02 Impact factor: 49.962

Review 2. Cell-type specific regulation of a kappa immunoglobulin gene by promoter and enhancer elements.

Authors: C Queen; J Foster; C Stauber; J Stafford
Journal: Immunol Rev Date: 1986-02 Impact factor: 12.988

3. Multiple nuclear factors interact with the immunoglobulin enhancer sequences.

Authors: R Sen; D Baltimore
Journal: Cell Date: 1986-08-29 Impact factor: 41.582

4. Interferon-gamma induces light chain synthesis in interleukin 2 stimulated human B cells.

Authors: C Queen; A S Fauci
Journal: Eur J Immunol Date: 1986-05 Impact factor: 5.532

5. SV40 DNA transfection of cells in suspension: analysis of efficiency of transcription and translation of T-antigen.

Authors: G Chu; P A Sharp
Journal: Gene Date: 1981-03 Impact factor: 3.688

6. Immunoglobulin gene transcription is activated by downstream sequence elements.

Authors: C Queen; D Baltimore
Journal: Cell Date: 1983-07 Impact factor: 41.582

Review 7. Regulation of immunoglobulin transcription.

Authors: C Queen
Journal: Oxf Surv Eukaryot Genes Date: 1984

8. A catalogue of splice junction sequences.

Authors: S M Mount
Journal: Nucleic Acids Res Date: 1982-01-22 Impact factor: 16.971

9. Expression of an immunoglobulin heavy chain gene transfected into lymphocytes.

Authors: R J Deans; K A Denis; A Taylor; R Wall
Journal: Proc Natl Acad Sci U S A Date: 1984-03 Impact factor: 11.205

10. Direct effect of interleukin 2 on the differentiation of human B cells which have not been preactivated in vitro.

Authors: A S Fauci
Journal: Eur J Immunol Date: 1985-11 Impact factor: 5.532

2 in total

1. Activation of immunoglobulin control elements in transgenic mice.

Authors: A E Miller; D L Ennist; K Ozato; H Westphal
Journal: Immunogenetics Date: 1992 Impact factor: 2.846

2. Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.

Authors: R A Currie; R G Roeder
Journal: Mol Cell Biol Date: 1989-10 Impact factor: 4.272

2 in total