Literature DB >> 31209293

Advances in stem cell research and therapeutic development.

Michele De Luca1, Alessandro Aiuti2,3, Giulio Cossu4, Malin Parmar5,6, Graziella Pellegrini7, Pamela Gehron Robey8.   

Abstract

Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies has remained small. In this Review, we survey advances in stem cell research and describe the cell types that are currently being used in the clinic or are close to clinical trials. Finally, we analyse the scientific rationale, experimental approaches, caveats and results underpinning the clinical use of such stem cells.

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Year:  2019        PMID: 31209293     DOI: 10.1038/s41556-019-0344-z

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


  59 in total

Review 1.  Gene therapy using haematopoietic stem and progenitor cells.

Authors:  Giuliana Ferrari; Adrian J Thrasher; Alessandro Aiuti
Journal:  Nat Rev Genet       Date:  2020-12-10       Impact factor: 53.242

2.  The Isolation and Manufacture of GMP-Grade Bone Marrow Stromal Cells from Bone Specimens.

Authors:  Rhayra B Dias; Danielle C Bonfim
Journal:  Methods Mol Biol       Date:  2021

Review 3.  Stem cell therapy: old challenges and new solutions.

Authors:  Carmela Rita Balistreri; Elena De Falco; Antonella Bordin; Olga Maslova; Alexander Koliada; Alexander Vaiserman
Journal:  Mol Biol Rep       Date:  2020-03-03       Impact factor: 2.316

4.  Glial restricted precursor delivery of dendrimer N-acetylcysteine promotes migration and differentiation following transplant in mouse white matter injury model.

Authors:  Christina L Nemeth; Sophia N Tomlinson; Rishi Sharma; Anjali Sharma; Sujatha Kannan; Rangaramanujam M Kannan; Ali Fatemi
Journal:  Nanoscale       Date:  2020-07-29       Impact factor: 7.790

5.  CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.

Authors:  Chih-Hao Wang; Morten Lundh; Accalia Fu; Rókus Kriszt; Tian Lian Huang; Matthew D Lynes; Luiz O Leiria; Farnaz Shamsi; Justin Darcy; Bennett P Greenwood; Niven R Narain; Vladimir Tolstikov; Kyle L Smith; Brice Emanuelli; Young-Tae Chang; Susan Hagen; Nika N Danial; Michael A Kiebish; Yu-Hua Tseng
Journal:  Sci Transl Med       Date:  2020-08-26       Impact factor: 17.956

Review 6.  Toward Combined Cell and Gene Therapy for Genodermatoses.

Authors:  Laura De Rosa; Maria Carmela Latella; Alessia Secone Seconetti; Cecilia Cattelani; Johann W Bauer; Sergio Bondanza; Michele De Luca
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-05-01       Impact factor: 10.005

Review 7.  Metabolomic Applications in Stem Cell Research: a Review.

Authors:  Daniela S C Bispo; Catarina S H Jesus; Inês M C Marques; Katarzyna M Romek; Mariana B Oliveira; João F Mano; Ana M Gil
Journal:  Stem Cell Rev Rep       Date:  2021-06-16       Impact factor: 5.739

8.  National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration.

Authors:  Robert E Hynds; William J Zacharias; Marko Z Nikolić; Melanie Königshoff; Oliver Eickelberg; Reinoud Gosens; Paolo de Coppi; Sam M Janes; Edward Morrisey; Hans Clevers; Amy L Ryan; Barry R Stripp; Xin Sun; Carla F Kim; Qing S Lin
Journal:  Am J Respir Cell Mol Biol       Date:  2021-07       Impact factor: 6.914

Review 9.  Regenerative medicine clinical readiness.

Authors:  Satsuki Yamada; Atta Behfar; Andre Terzic
Journal:  Regen Med       Date:  2021-02-24       Impact factor: 3.806

10.  Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras.

Authors:  Toshiya Nishimura; Fabian P Suchy; Joydeep Bhadury; Kyomi J Igarashi; Carsten T Charlesworth; Hiromitsu Nakauchi
Journal:  Cell Stem Cell       Date:  2020-12-28       Impact factor: 24.633

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