Literature DB >> 33625958

National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration.

Robert E Hynds1,2, William J Zacharias3, Marko Z Nikolić2, Melanie Königshoff4,5, Oliver Eickelberg4, Reinoud Gosens6,7, Paolo de Coppi8, Sam M Janes2, Edward Morrisey9,10,11, Hans Clevers12,13,14, Amy L Ryan15,16, Barry R Stripp17,18, Xin Sun19,20, Carla F Kim21,22,23,24, Qing S Lin25.   

Abstract

The National Heart, Lung, and Blood Institute of the National Institutes of Health, together with the Longfonds BREATH consortium, convened a working group to review the field of lung regeneration and suggest avenues for future research. The meeting took place on May 22, 2019, at the American Thoracic Society 2019 conference in Dallas, Texas, United States, and brought together investigators studying lung development, adult stem-cell biology, induced pluripotent stem cells, biomaterials, and respiratory disease. The purpose of the working group was 1) to examine the present status of basic science approaches to tackling lung disease and promoting lung regeneration in patients and 2) to determine priorities for future research in the field.

Entities:  

Keywords:  chronic lung disease; lung injury; lung regeneration; stem cells

Mesh:

Year:  2021        PMID: 33625958      PMCID: PMC8320125          DOI: 10.1165/rcmb.2020-0397WS

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN: 1044-1549            Impact factor:   6.914


  72 in total

1.  Type 2 alveolar cells are stem cells in adult lung.

Authors:  Christina E Barkauskas; Michael J Cronce; Craig R Rackley; Emily J Bowie; Douglas R Keene; Barry R Stripp; Scott H Randell; Paul W Noble; Brigid L M Hogan
Journal:  J Clin Invest       Date:  2013-06-10       Impact factor: 14.808

Review 2.  Lung organoids: current uses and future promise.

Authors:  Christina E Barkauskas; Mei-I Chung; Bryan Fioret; Xia Gao; Hiroaki Katsura; Brigid L M Hogan
Journal:  Development       Date:  2017-03-15       Impact factor: 6.868

3.  Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.

Authors:  Katherine B McCauley; Finn Hawkins; Maria Serra; Dylan C Thomas; Anjali Jacob; Darrell N Kotton
Journal:  Cell Stem Cell       Date:  2017-03-30       Impact factor: 24.633

4.  Expression of mutant Sftpc in murine alveolar epithelia drives spontaneous lung fibrosis.

Authors:  Shin-Ichi Nureki; Yaniv Tomer; Alessandro Venosa; Jeremy Katzen; Scott J Russo; Sarita Jamil; Matthew Barrett; Vivian Nguyen; Meghan Kopp; Surafel Mulugeta; Michael F Beers
Journal:  J Clin Invest       Date:  2018-08-13       Impact factor: 14.808

5.  Analysis of tissues following mesenchymal stromal cell therapy in humans indicates limited long-term engraftment and no ectopic tissue formation.

Authors:  L von Bahr; I Batsis; G Moll; M Hägg; A Szakos; B Sundberg; M Uzunel; O Ringden; K Le Blanc
Journal:  Stem Cells       Date:  2012-07       Impact factor: 6.277

6.  Long-term culture and cloning of primary human bronchial basal cells that maintain multipotent differentiation capacity and CFTR channel function.

Authors:  Jennifer R Peters-Hall; Melissa L Coquelin; Michael J Torres; Ryan LaRanger; Busola R Alabi; Sei Sho; Jose F Calva-Moreno; Philip J Thomas; Jerry W Shay
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2018-05-03       Impact factor: 5.464

7.  A biphasic chamber system for maintaining polarity of differentiation of cultured respiratory tract epithelial cells.

Authors:  M J Whitcutt; K B Adler; R Wu
Journal:  In Vitro Cell Dev Biol       Date:  1988-05

8.  A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Authors:  Daniel T Montoro; Adam L Haber; Moshe Biton; Vladimir Vinarsky; Brian Lin; Susan E Birket; Feng Yuan; Sijia Chen; Hui Min Leung; Jorge Villoria; Noga Rogel; Grace Burgin; Alexander M Tsankov; Avinash Waghray; Michal Slyper; Julia Waldman; Lan Nguyen; Danielle Dionne; Orit Rozenblatt-Rosen; Purushothama Rao Tata; Hongmei Mou; Manjunatha Shivaraju; Hermann Bihler; Martin Mense; Guillermo J Tearney; Steven M Rowe; John F Engelhardt; Aviv Regev; Jayaraj Rajagopal
Journal:  Nature       Date:  2018-08-01       Impact factor: 49.962

9.  Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs.

Authors:  Gianni Carraro; Apoorva Mulay; Changfu Yao; Takako Mizuno; Bindu Konda; Martin Petrov; Daniel Lafkas; Joe R Arron; Cory M Hogaboam; Peter Chen; Dianhua Jiang; Paul W Noble; Scott H Randell; Jonathan L McQualter; Barry R Stripp
Journal:  Am J Respir Crit Care Med       Date:  2020-12-01       Impact factor: 21.405

10.  Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis.

Authors:  Taylor S Adams; Jonas C Schupp; Sergio Poli; Ehab A Ayaub; Nir Neumark; Farida Ahangari; Sarah G Chu; Benjamin A Raby; Giuseppe DeIuliis; Michael Januszyk; Qiaonan Duan; Heather A Arnett; Asim Siddiqui; George R Washko; Robert Homer; Xiting Yan; Ivan O Rosas; Naftali Kaminski
Journal:  Sci Adv       Date:  2020-07-08       Impact factor: 14.136

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