| Literature DB >> 3120710 |
K Uchida1, T Morita, T Sato, T Ogura, R Yamashita, S Noguchi, H Suzuki, H Nyunoya, M Miwa, T Sugimura.
Abstract
The complete nucleotide sequence of human fibroblast poly(ADP-ribose) polymerase cDNA was determined. The cDNA contains an open reading frame for a 1014 amino acid polypeptide. In the DNA binding domain of poly(ADP-ribose) polymerase, there are predicted alpha-helix-turn-alpha-helix structures and two sequences each of about 100 amino acids that are similar to each other containing potential cysteine-zinc DNA binding structures. Within the 3' untranslated region, there is an AT-rich sequence containing ATTTA, a possible mRNA destabilizer.Entities:
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Year: 1987 PMID: 3120710 DOI: 10.1016/0006-291x(87)90921-1
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575