Literature DB >> 312013

Mapping of the structural gene for the second component of complement with respect to the human major histocompatibility complex.

D Raum, D Glass, C B Carpenter, P H Schur, C A Alper.   

Abstract

Families have been HLA typed, and allotypes of the second component of complement and properdin factor B determined. The lod score for the C2 structural gene and HLA-B from the study of 11 families and 55 informative meioses was 14.39 at maximum likelihood estimate of the recombination fraction of .02. This is related to other estimates of the distance between these two genes. The relative kinetic activities of the C2 allotypes were studied and no differences were demonstrated. No crossovers between Bf and C2 were observed.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 312013      PMCID： PMC1685669     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  22 in total

1.  On the HLA-B,D map distance.

Authors:  L U Lamm; T Kristensen; F Kissmeyer-Nielsen; F Jørgensen
Journal:  Tissue Antigens       Date:  1977-11

2.  Very close linkage between HLA-B and Bf inferred from allelic association.

Authors:  A Arnason; B Larsen; W H Marshall; J H Edwards; P Macintosh; B Olaisen; P Teisberg
Journal:  Nature       Date:  1977-08-11       Impact factor: 49.962

3.  Structural heterogeneity of C2 Complement protein and its genetic variants in man: a new polymorphism of the HLA region.

Authors:  T Meo; J P Atkinson; M Bernoco; D Bernoco; R Ceppellini
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

Review 4.  Allotypes of complement components in man.

Authors:  M J Hobart; P J Lachmann
Journal:  Transplant Rev       Date:  1976

5.  Estimating distances from the centromere by means of benign ovarian teratomas in man.

Authors:  J Ott; D Linder; B K McCaw; E W Lovrien; F Hecht
Journal:  Ann Hum Genet       Date:  1976-11       Impact factor: 1.670

6.  Inherited deficiency of the second component of complement. Rheumatic disease associations.

Authors:  D Glass; D Raum; D Gibson; J S Stillman; P H Schur
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

7.  The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement.

Authors:  D Raum; D Glass; C B Carpenter; C A Alper; P H Schur
Journal:  J Clin Invest       Date:  1976-11       Impact factor: 14.808

8.  Assignment of the major histocompatibility complex to a region of the short arm of human chromosome 6.

Authors:  U Francke; M A Pellegrino
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

9.  Inherited structural polymorphism in human C2: evidence for genetic linkage between C2 and Bf.

Authors:  C A Alper
Journal:  J Exp Med       Date:  1976-10-01       Impact factor: 14.307

10.  Genetic polymorphism in human glycine-rich beta-glycoprotein.

Authors:  C A Alper; T Boenisch; L Watson
Journal:  J Exp Med       Date:  1972-01       Impact factor: 14.307
View more
  15 in total

1.  Nomenclature for human complement component C2. WHO-IUIS Nomenclature Sub-Committee.

Authors: 
Journal:  Bull World Health Organ       Date:  1992       Impact factor: 9.408

2.  A restriction fragment of the C2 gene is a unique marker for C2 deficiency and the uncommon C2 allele C2*B (a marker for type 1 diabetes).

Authors:  S Simon; Z Awdeh; R D Campbell; P Ronco; S J Brink; G S Eisenbarth; E J Yunis; C A Alper
Journal:  J Clin Invest       Date:  1991-12       Impact factor: 14.808

3.  Immunofixation for C2 typing: C2 allotypes in Spaniards in relation to HLA, Bf and C4.

Authors:  J R Regueiro; A Arnaiz-Villena
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

4.  Polymorphism of human C2 detected by immunoblotting.

Authors:  G Doxiadis; I Doxiadis; H Grosse-Wilde
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 5.  Molecular genetics of the major histocompatibility linked complement genes.

Authors:  H R Colten
Journal:  Springer Semin Immunopathol       Date:  1983

6.  The location of C2, C4, and BF relative to HLA-B and HLA-D.

Authors:  D D Raum; Z L Awdeh; D Glass; E Yunis; C A Alper
Journal:  Immunogenetics       Date:  1981-03-01       Impact factor: 2.846

7.  Genetic polymorphism of human plasminogen.

Authors:  D Raum; D Marcus; C A Alper
Journal:  Am J Hum Genet       Date:  1980-09       Impact factor: 11.025

8.  H-2-linked murine factor B phenotypes.

Authors:  E S Paolucci; D C Shreffler
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

9.  Polymorphism of properdin factor B in Japanese. Description of a rare variant and data of association with HLA and C2.

Authors:  K Tokunaga; C Araki; T Juji; K Omoto
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

10.  Structural polymorphism of mouse complement C2 detected by microscale peptide mapping: linkage to H-2.

Authors:  S Takahashi; Y Fukuoka; K Moriwaki; T Okuda; T Tachibana; S Natsuume-Sakai; M Takahashi
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.