Literature DB >> 31191197

Extension of the Storage Period of Platelet Concentrates in Germany to 5 Days by Bacterial Testing: Is it Worth the Effort?

Tanja Vollmer1, Dennis Hinse1, Jürgen Diekmann1, Cornelius Knabbe1, Jens Dreier1.   

Abstract

The shelf life of platelet concentrates (PCs) was limited in Germany to 4 days after the day of production because platelet-related septic complications had been observed, mainly with PCs at the end of their shelf life. The reduction in PC shelf life gives rise to several problems, including an increased number of discarded products, accompanied by potential challenges of how to ensure an adequate supply of platelet products. The aim of this study was to show routine experience over the last 7 years using the Bactiflow (BF) assay to screen for bacterial contamination late in PC storage, followed by extension of PC shelf life.

Keywords:  Bacterial screening; BactiFlow; Extension of shelf life; Platelet concentrates

Year:  2019        PMID: 31191197      PMCID: PMC6514479          DOI: 10.1159/000499543

Source DB:  PubMed          Journal:  Transfus Med Hemother        ISSN: 1660-3796            Impact factor:   3.747


  7 in total

1.  Detection of bacterial contamination in platelet concentrates by a sensitive flow cytometric assay (BactiFlow): a multicentre validation study.

Authors:  T Vollmer; J Dreier; V Schottstedt; J Bux; K Tapernon; W Sibrowski; K Kleesiek; C Knabbe
Journal:  Transfus Med       Date:  2012-06-25       Impact factor: 2.019

2.  [Regulations stability time of platelet concentration for the purpose of reducing life threatening septic transfusion reactions through bacterial contamination: from the 66th meeting of the Working Group on Blood on 9 June 2008 as adopted following (V 38)].

Authors: 
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2008-12       Impact factor: 1.513

3.  Late sampling for automated culture to extend the platelet shelf life to 5 days in Germany.

Authors:  Tanja Vollmer; Mareike Dabisch-Ruthe; Melanie Weinstock; Cornelius Knabbe; Jens Dreier
Journal:  Transfusion       Date:  2018-04-15       Impact factor: 3.157

4.  Extension of platelet shelf life from 4 to 5 days by implementation of a new screening strategy in Germany.

Authors:  W Sireis; B Rüster; C Daiss; M K Hourfar; G Capalbo; H-U Pfeiffer; K Janetzko; M Goebel; V A J Kempf; E Seifried; M Schmidt
Journal:  Vox Sang       Date:  2011-04-25       Impact factor: 2.144

5.  Bacterial screening by flow cytometry offers potential for extension of platelet storage: results of 14 months of active surveillance.

Authors:  T Vollmer; J Engemann; K Kleesiek; J Dreier
Journal:  Transfus Med       Date:  2011-01-27       Impact factor: 2.019

6.  Routine bacterial screening of platelet concentrates by flow cytometry and its impact on product safety and supply.

Authors:  B Müller; G Walther-Wenke; M Kalus; T Alt; J Bux; T Zeiler; V Schottstedt
Journal:  Vox Sang       Date:  2014-12-03       Impact factor: 2.144

Review 7.  Diagnostic methods for platelet bacteria screening: current status and developments.

Authors:  Melanie Störmer; Tanja Vollmer
Journal:  Transfus Med Hemother       Date:  2013-12-30       Impact factor: 3.747

  7 in total
  1 in total

1.  Expanded validation of the effect and quality of a pathogen inactivation system based on riboflavin photochemistry on platelet bacterial contamination.

Authors:  Bin Fan; Meng Yi; Guang Yang; Lu Yang; Wei Shang; Yi Liu; Xiaolong Zhong; Liguo Zhu; Deqing Wang
Journal:  Ann Transl Med       Date:  2021-12
  1 in total

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