Literature DB >> 3117085

Placental transfer and neonatal elimination of mono-unsaturated metabolites of valproic acid.

T Kondo, K Otani, T Hirano, S Kaneko.   

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Year:  1987        PMID： 3117085      PMCID： PMC1386266          DOI： 10.1111/j.1365-2125.1987.tb03189.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


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  7 in total

1.  Valproic acid and spina bifida.

Authors:  T Bjerkedal; A Czeizel; J Goujard; B Kallen; P Mastroiacova; N Nevin; G Oakley; E Robert
Journal:  Lancet       Date:  1982-11-13       Impact factor: 79.321

2.  Transplacental passage and half-life of sodium valproate in infants born to epileptic mothers.

Authors:  S Kaneko; K Otani; Y Fukushima; T Sato; Y Nomura; Y Ogawa
Journal:  Br J Clin Pharmacol       Date:  1983-04       Impact factor: 4.335

3.  Valproic acid and metabolites: pharmacological and toxicological studies.

Authors:  H Nau; W Löscher
Journal:  Epilepsia       Date:  1984       Impact factor: 5.864

4.  Valproic acid in the perinatal period: decreased maternal serum protein binding results in fetal accumulation and neonatal displacement of the drug and some metabolites.

Authors:  H Nau; H Helge; W Luck
Journal:  J Pediatr       Date:  1984-04       Impact factor: 4.406

5.  Differential transplacental binding of valproic acid: influence of free fatty acids.

Authors:  F Albani; R Riva; M Contin; A Baruzzi; M Altomare; G P Merlini; E Perucca
Journal:  Br J Clin Pharmacol       Date:  1984-06       Impact factor: 4.335

6.  Abnormal metabolism of valproic acid in fatal hepatic failure.

Authors:  W Kochen; A Schneider; A Ritz
Journal:  Eur J Pediatr       Date:  1983-10       Impact factor: 3.183

7.  Valproic acid and its metabolites: placental transfer, neonatal pharmacokinetics, transfer via mother's milk and clinical status in neonates of epileptic mothers.

Authors:  H Nau; D Rating; S Koch; I Häuser; H Helge
Journal:  J Pharmacol Exp Ther       Date:  1981-12       Impact factor: 4.030
  7 in total
  2 in total

1.  The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, co-medication, and the presence of spina bifida.

Authors:  J G Omtzigt; H Nau; F J Los; L Pijpers; D Lindhout
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

2.  NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects.

Authors:  Eduardo B Sequerra; Raman Goyal; Patricio A Castro; Jacqueline B Levin; Laura N Borodinsky
Journal:  J Neurosci       Date:  2018-04-30       Impact factor: 6.167
  2 in total

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