Literature DB >> 6325140

Valproic acid and metabolites: pharmacological and toxicological studies.

H Nau, W Löscher.   

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Year:  1984        PMID： 6325140     DOI： 10.1111/j.1528-1157.1984.tb05632.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN： 0013-9580            Impact factor:   5.864


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  22 in total

1.  The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, co-medication, and the presence of spina bifida.

Authors:  J G Omtzigt; H Nau; F J Los; L Pijpers; D Lindhout
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

2.  Case files of the Children's Hospital of Michigan Regional Poison Control Center: the use of carnitine for the management of acute valproic acid toxicity.

Authors:  Abhishek Katiyar; Cynthia Aaron
Journal:  J Med Toxicol       Date:  2007-09

3.  Pharmacokinetics, anticonvulsant efficacy, and adverse effects of trans-2-en-valproate after acute and chronic administration in amygdala-kindled rats.

Authors:  D Hönack; C Rundfeldt; W Löscher
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-02       Impact factor: 3.000

4.  The effects of phenytoin and carbamazepine on serum concentrations of mono-unsaturated metabolites of valproic acid.

Authors:  T Kondo; K Otani; T Hirano; S Kaneko; Y Fukushima
Journal:  Br J Clin Pharmacol       Date:  1990-01       Impact factor: 4.335

5.  Placental transfer and neonatal elimination of mono-unsaturated metabolites of valproic acid.

Authors:  T Kondo; K Otani; T Hirano; S Kaneko
Journal:  Br J Clin Pharmacol       Date:  1987-09       Impact factor: 4.335

Review 6.  The risk-benefit ratio of anticonvulsant drugs.

Authors:  M J Eadie
Journal:  Med Toxicol Adverse Drug Exp       Date:  1987 Sep-Oct

Review 7.  Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain.

Authors:  W Löscher
Journal:  Neurochem Res       Date:  1993-04       Impact factor: 3.996

Review 8.  Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy.

Authors:  Wolfgang Löscher
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

Review 9.  Valproate-associated hepatotoxicity and its biochemical mechanisms.

Authors:  M J Eadie; W D Hooper; R G Dickinson
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Mar-Apr

10.  Valproic acid is a novel activator of AMP-activated protein kinase and decreases liver mass, hepatic fat accumulation, and serum glucose in obese mice.

Authors:  Lindsay B Avery; Namandjé N Bumpus
Journal:  Mol Pharmacol       Date:  2013-10-08       Impact factor: 4.436
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